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Search Results for " liver-intestine "
Targets Recommended: Others

5

抑制剂 & 化合物

3

天然产物

55

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T21867 BI-6015

2-甲基-1-(2-甲基-5-硝基苯基磺酰基)-1H-苯并[D]咪唑

Others Others
BI 6015 是肝细胞核因子 4α (HNF4α) 拮抗剂,可抑制已知 HNF4α 靶基因的表达。它利用 HNF4α 拮抗作用,降低胰岛素启动子活性,可用于研究癌症和糖尿病。
T3625 Bempedoic acid

ETC1002,ESP-55016,ETC 1002,ETC-1002

ATP Citrate Lyase; AMPK Chromatin/Epigenetic; Metabolism; PI3K/Akt/mTOR signaling
Bempedoic acid (ETC1002) 是一种 ATP-柠檬酸裂解酶抑制剂,可激活AMPK。它是脂质和碳水化合物代谢的调节剂。
T60641 Vanin-1-IN-2

Vanin-1-IN-2 是vanin-1的有效抑制剂(IC 50 = 162 nM)。Vanin-1 是在肾脏、肝脏和小肠中高水平表达的细胞表面相关的糖基磷脂酰肌醇 (GPI) 锚定蛋白。
T71055 Albendazole-d7

Albendazole-d7 is intended for use as an internal standard for the quantification of albendazole by GC- or LC-MS. Albendazole is an orally bioavailable benzimidazole anthelmintic that is active against a variety of helminths, including liver flukes, tapeworms, and roundworms. It eliminates Trichostrongylus in the fourth stomach of cattle and sheep when orally administered at doses ranging from 2.5 to 10 mg/kg as well as other species in the fourth stomach and the small and large intestine. Alben...
T13262 FCE 28654

FCE 28654 is a water-soluble acyl-CoA inhibitor.

化合物

BI-6015
Cat.No: T21867
Synonym: 2-甲基-1-(2-甲基-5-硝基苯基磺酰基)-1H-苯并[D]咪唑
Target: Others
Bempedoic acid
Cat.No: T3625
Synonym: ETC1002,ESP-55016,ETC 1002,ETC-1002
Target: ATP Citrate Lyase, AMPK
Vanin-1-IN-2
Cat.No: T60641
Synonym:
Target:
Albendazole-d7
Cat.No: T71055
Synonym:
Target:
FCE 28654
Cat.No: T13262
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T13506 3β-Ursodeoxycholic acid

Isoursodeoxycholic acid

3β-Ursodeoxycholic acid (Isoursodeoxycholic acid) 是一种胆汁酸。3β-Ursodeoxycholic acid 经口服给药表现出良好的耐受性和良好的肠道吸收能力。3β-Ursodeoxycholic acid 可以在肠道和肝脏经历酶异构化,并生成UDCA。
T74293 Allolithocholic acid

Allolithocholic acid 是一种类固醇酸,在正常血清和粪便中可发现。该化合物促进脂肪与甾醇在肠道及肝脏的排泄、吸收与运输。
T37810 6',7'-Epoxybergamottin

6'7'-Epoxybergamottin is a furanocoumarin found in grapefruit. It is a potent inhibitor of the cytochrome P450 (CYP) isoform CYP3A4 with an IC50 value of 0.30 ppm in a cell-free assay, 0.33 μM in HL7 human liver cells, and 0.22 μM in S9 human intestine cells. It has been studied in the context of drug interactions with grapefruit constituents. It is found in grapefruit juice at concentrations of 0.1-7.4 μM and inhibits the transport of talinolol , a permeability glycoprotein (P-gp/ABCB1) transpo...

天然产物

3β-Ursodeoxycholic acid
Cat.No: T13506
Synonym: Isoursodeoxycholic acid
Target:
Allolithocholic acid
Cat.No: T74293
Synonym:
Target:
6',7'-Epoxybergamottin
Cat.No: T37810
Synonym:
Target:
Cat. No. Product Name Species Expression System
TMPY-02919 Cadherin 17/CDH17 Protein, Rat, Recombinant (His)

cadherin 17, LI cadherin (liver-intestine)

Rat HEK293 Cells
Cadherin 17/CDH17 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 86.4 kDa and the accession number is P55281.
TMPY-05352 Cadherin 17/CDH17 Protein, Cynomolgus, Recombinant (hFc)

cadherin 17, LI cadherin (liver-intestine)

Cynomolgus HEK293 Cells
Cadherin 17/CDH17 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 111.8 kDa and the accession number is XP_005563762.1.
TMPY-01912 Cadherin 17/CDH17 Protein, Human, Recombinant (His)

HPT-1,cadherin 17, LI cadherin (liver-intestine...

Human HEK293 Cells
Cadherin 17/CDH17 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 87 kDa and the accession number is Q12864-1.
TMPY-06645 Cadherin 17/CDH17 Protein, Cynomolgus, Recombinant (His)

cadherin 17, LI cadherin (liver-intestine)

Cynomolgus HEK293 Cells
Cadherin 17/CDH17 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 85.94 kDa and the accession number is XP_005563762.2.
TMPY-06324 Cadherin 17/CDH17 Protein, Human, Recombinant (His & Avi), Biotinylated

cadherin 17, LI cadherin (liver-intestine)...

Human HEK293 Cells
Cadherin 17/CDH17 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 88.24 kDa and the accession number is Q12864-1.
TMPJ-00583 CDH17 Protein, Human, Recombinant (His)

Intestinal Peptide-Associated Transporter HPT-1,Liver

Human HEK293 Cells
Cadherin-17 is a single-pass type I membrane protein that belongs to the cadherin superfamily. Cadherin-17 consists of one extracellular region containing seven cadherin domains and one transmembrane region but it lacks the conserved cytoplasmic domain. Cadherin-17 is expressed in the gastrointestinal tract and pancreatic duct. Cadherins are calcium dependent cell adhesion proteins and preferentially interact with each other in a homophilic manner in connecting cells. Cadherin-17 may have a role...
TMPY-03221 Intrinsic Factor Protein, Human, Recombinant (His)

IF,IFMH,gastric intrinsic factor (vitamin B synthesis),INF,T...

Human HEK293 Cells
Gastric intrinsic factor, also known as GIF, belongs to the of the cobalamin transport protein family. It is a glycoprotein produced by the parietal cells of the stomach. Gastric intrinsic factor plays a key role in the absorption of vitamin B12 on in the small intestine. Vitamin B12 bounds to haptocorrin after entry into the stomach. The resulting complex enters the duodenum, where pancreatic enzymes digest haptocorrin. In the less acidic environment of the small intestine, B12 can then bind to...
TMPY-03274 CXCL11 Protein, Human, Recombinant

SCYB9B,I-TAC,chemokine (C-X-C motif) ligand 11,H174,SCYB11,I...

Human E. coli
I-TAC, also known as CXCL11, is a small cytokine belonging to the CXC chemokine family. It is highly expressed in peripheral blood leukocytes, pancreas and liver, with moderate levels in thymus, spleen and lung and low expression levels were in small intestine, placenta and prostate. The I-TAC chemokine elicits its effects on its target cells by interacting with the cell surface chemokine receptor CXCR3, with a higher affinity than do the other ligands for this receptor, CXCL9 and CXCL10. I-TAC ...
TMPJ-00662 RANKL/TNFSF11/CD254 Protein, Human, Recombinant (E. coli)

Receptor activator of nuclear factor kappa-B ligand,Receptor...

Human E. coli
CD254, also known as RANKL, TNFSF11, TRANCE, OPGL and ODF, is a type II membrane protein of the tumor necrosis factor (TNF) superfamily, and affects the immune system and control bone regeneration and remodeling. RANKL is the ligand of nuclear factor (NF)-κB (RANK). When RANKL binds to RANK, it will undergo trimerization and then bind to an adaptor molecule TNF receptor-associated factor 6 (TRAF6). This results in the activation of several downstream signaling cascades, including the NFκB, mitog...
TMPJ-00302 Serpin F2 Protein, Mouse, Recombinant (hFc)

Alpha-2-PI,α-2-antiplasmin,Alpha-2-AP,α-2-AP,Serpinf2,Alpha-...

Mouse HEK293 Cells
Alpha-2-antiplasmin, also called Serpin F2, is a serine protease inhibitor (serpin) responsible for inactivating plasmin, and an important enzyme participates in fibrinolysis and degradation of other proteins. In liver cirrhosis, there is decreased production of alpha 2-antiplasmin, leading to decreased inactivation of plasmin and an increase in fibrinolysis. Serpin F2 is major expressed on liver and kidney. Some other tissues such as muscle, intestine, central nervous system, and placenta also ...
TMPK-00947 CDH17 Protein, Human, Recombinant (His & Avi), Biotinylated

CDH16,Cdh17,P130,cadherin-16,HPT-1,LI-cadherin,Cadherin-17,B...

Human HEK293 Cells
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. CDH17 Protein, Human, Recombinant (His & Avi), Biotinylated...
TMPK-00952 CDH17 Domain 3 & 4 Protein, Human, Recombinant (mFc)

BILL-cadherin,Cadherin-17,LI-cadherin,CDH16,cadherin-16,Cdh1...

Human HEK293 Cells
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. CDH17 Domain 3 & 4 Protein, Human, Recombinant (mFc) is exp...
TMPY-01579 GBA3 Protein, Human, Recombinant (His)

glucosidase, beta, acid 3 (gene/pseudogene),GBA3,MGC126878,K...

Human Baculovirus Insect Cells
Cytosolic beta-glucosidase, also known as Cytosolic beta-glucosidase-like protein 1, GBA3, CBG and CBGL1 is a cytoplasm protein which belongs to theglycosyl hydrolase 1 family and Klotho subfamily. GBA3 / CBGL1 is a glycosidase probably involved in the intestinal absorption and metabolism of dietary flavonoid glycosides. GBA3 / CBGL1 is present in small intestine (at protein level). GBA3 / CBGL1 is expressed in liver, small intestine, colon, spleen and kidney. GBA3 / CBGL1 is down-regulated in r...
TMPK-01224 CDH17 Protein (Primary Amine Labeling), Mouse, Recombinant (His), Biotinylated

P130,BILL-cadherin,LI-cadherin,MGC138218,FLJ26931,CDH16,Cadh...

Mouse HEK293 Cells
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. CDH17 Protein (Primary Amine Labeling), Mouse, Recombinant ...
TMPK-00949 CDH17 Domain 7 Protein, Human, Recombinant (hFc)

CDH16,P130,MGC142024,Cdh17,FLJ26931,Cadherin-17,MGC138218,ca...

Human HEK293 Cells
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. CDH17 Domain 7 Protein, Human, Recombinant (hFc) is express...
TMPY-03867 CBR3 Protein, Human, Recombinant (His)

SDR21C2,carbonyl reductase 3,hCBR3,HEL-S-25

Human E. coli
CBR3, also known as hCBR3, belongs to the short-chain dehydrogenases/reductases (SDR) family. CBR3 is expressed in ovary, pancreas, intestine, colon, kidney, brain, thymus, lung, heart, liver, spleen, leukocyte, prostate and testis. It is a monomeric NADPH-dependent oxidoreductase and is closely linked to another carbonyl reductase gene – CBR1. CBR3 catalyzes the reduction of a large number of biologically and pharmacologically active carbonyl compounds to their corresponding alcohols. It has lo...
TMPK-01087 Apolipoprotein A-V/APOA5 Protein, Mouse, Recombinant (His)

ApoA-V,Apolipoprotein A-V,Rap3,Apoa5,Apo-AV,Apolipoprotein A...

Mouse E. coli
APOA5 is probably the gene with the strongest effect on triglyceride (TG) metabolism. APOA5 is almost exclusively expressed in the liver, and its product apoAV has a very low circulating concentration. New physiological roles of apoAV have been recently elucidated, such as control of chylomicron production in the intestine and TG accumulation in adipose tissue.The key role of APOA5 in TG metabolism has been largely shown through genetic studies in association with either severe or moderate hyper...
TMPJ-00962 AKR1C3 Protein, Human, Recombinant (His)

3-Alpha-HSD Type 2,17-β-Hydroxysteroid Dehydrogenase Type 5,...

Human HEK293 Cells
AKR1C3, is an enzyme which belongs to the aldo/keto reductase family. It is expressed in many tissues including adrenal gland, brain, kidney, liver, lung, mammary gland, placenta, small intestine, colon, spleen, prostate and testis. AKR1C3 catalyzes the conversion of aldehydes and ketones to alcohols. It catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ) and the oxidation of 9-alpha,11-beta-PGF2 to PGD2,which functions as a bi-directional 3-alpha-, 17-beta- and ...
TMPK-00950 CDH17 Domain 6-7 Protein, Human, Recombinant (hFc)

HPT-1,P130,MGC138218,LI-cadherin,FLJ26931,cadherin-16,Cdh17,...

Human HEK293 Cells
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. CDH17 Domain 6-7 Protein, Human, Recombinant (hFc) is expre...
TMPK-00473 CDH17 Protein, Rhesus macaque, Recombinant (His)

CDH16,Cdh17,MGC142024,Cadherin-17,cadherin-16,P130,MGC138218...

Rhesus HEK293 Cells
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. CDH17 Protein, Rhesus macaque, Recombinant (His) is express...
TMPK-01223 CDH17 Protein, Mouse, Recombinant (His)

CDH16,LI-cadherin,Cdh17,MGC138218,HPT-1,MGC142024,FLJ26931,B...

Mouse HEK293 Cells
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. CDH17 Protein, Mouse, Recombinant (His) is expressed in HEK...
TMPK-00948 CDH17 Protein, Human, Recombinant (hFc)

Cdh17,cadherin-16,FLJ26931,Cadherin-17,HPT-1,P130,CDH16,LI-c...

Human HEK293 Cells
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. CDH17 Protein, Human, Recombinant (hFc) is expressed in HEK...
TMPK-00555 CDH17 Protein, Cynomolgus, Recombinant (His)

Cdh17,HPT-1,FLJ26931,LI-cadherin,BILL-cadherin,P130,Cadherin...

Cynomolgus HEK293 Cells
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. CDH17 Protein, Cynomolgus, Recombinant (His) is expressed i...
TMPK-00953 CDH17 Domain 6-7 Protein, Human, Recombinant (mFc)

Cdh17,CDH16,MGC138218,BILL-cadherin,HPT-1,cadherin-16,MGC142...

Human HEK293 Cells
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. CDH17 Domain 6-7 Protein, Human, Recombinant (mFc) is expre...
TMPY-01099 GPT Protein, Rat, Recombinant (His)

Gpt1,ALAT,glutamic-pyruvate transaminase (alanine aminotrans...

Rat Baculovirus Insect Cells
Alanine aminotransferase (ALT), also known as glutamate pyruvate transaminase (GPT), is a pyridoxal enzyme that belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family, Alanine aminotransferase subfamily. Gpt / Gpt1 / ALT catalyzes the reversible interconversion of L-alanine and 2-oxoglutalate to pyruvate and L-glutamate and plays a key role in the intermediary metabolism of glucose and amino acids. Gpt / Gpt1 / ALT is expressed in the liver, kidney, heart, and skeletal musc...
TMPY-04058 RGS5 Protein, Human, Recombinant (His)

MST106,MSTP032,MST092,regulator of G-protein signaling 5,MST...

Human E. coli
RGS5 is a member of the RGS superfamily and acts as a negative regulator of heterotrimeric G protein-mediated signalling through G protein-coupled receptors (GPCRs). The regulator of G-protein signaling (RGS) proteins have recently been identified as signal transduction molecules which have structural homology to SST2 of Saccharomyces cerevisiae and EGL-10 of Caenorhabditis elegans. The messenger RNA of hRGS5 was abundantly expressed in heart, lung, skeletal muscle, and small intestine, and at l...
TMPJ-00349 RANK/TNFRSF11A Protein, Human, Recombinant (aa 30-212, His)

CD265 antigen,FEO,TRANCER,ODFR,ODFROSTS,TRANCE R,TNFRSF11A,O...

Human HEK293 Cells
Receptor Activator of Nuclear Factor κ B (RANK), also known as CD265, TRANCE Receptor or TNFRSF11A, is member of the tumor necrosis factor receptor (TNFR) molecular superfamily. RANK is the receptor for RANK-Ligand (RANKL) and part of the RANK/RANKL/OPG signaling pathway that regulates osteoclast differentiation and activation. It plays a vital role in bone remodeling and repair, immune cell function, lymph node development, thermal regulation, and mammary gland development. RANK is constitutive...
TMPY-03330 BPHL Protein, Human, Recombinant (His)

biphenyl hydrolase-like (serine hydrolase),VACVASE,MCNAA,BPH...

Human E. coli
BPHL is a member of the serine protease family. BPHL is expressed large quantities in liver and kidney and in minor quantities in heart, intestine and skeletal muscle. BPHL is a specific alpha-amino acid ester hydrolase that prefers small, hydrophobic, and aromatic side chains and does not have a stringent requirement for the leaving group other than preferring a primary alcohol. It catalyzes the hydrolytic activation of amino acid ester prodrugs of nucleoside analogs such as valacyclovir ...
TMPK-00951 CDH17 Domain 5-7 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated

FLJ26931,CDH16,LI-cadherin,MGC138218,cadherin-16,Cadherin-17...

Human HEK293 Cells
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. CDH17 Domain 5-7 Protein (Primary Amine Labeling), Human, R...
TMPY-01100 GPT2 Protein, Rat, Recombinant (His)

glutamic pyruvate transaminase (alanine aminotransferase) 2

Rat Baculovirus Insect Cells
Alanine aminotransferase (ALT), also known as glutamate pyruvate transaminase (Gpt), is a pyridoxal enzyme that catalyzes the reversible interconversion of L-alanine and 2-oxoglutalate to pyruvate and L-glutamate and plays a key role in the intermediary metabolism of glucose and amino acids. As a key enzyme for gluconeogenesis, Gpt is a widely-used serum marker for liver injury. Two ALT isoenzymes have been identified, ALT1 and ALT2 (GPT1 and GPT2), which are encoded by separate genes and share ...
TMPJ-01224 FGFRL1 Protein, Human, Recombinant (His)

FGFR5,FGFR-5,FGFRL1,FGFR-Like Protein,FHFR,FGF Homologous Fa...

Human HEK293 Cells
Fibroblast Growth Factor Receptor-Like 1 (FGFRL1) is a single-pass type I membrane protein that belongs to the FGF receptor family. The mature human FGFRL1 consists of a 354 amino acid extracellular domain (ECD) with 3 Ig-like C2-type domains, a 21 amino acid transmembrane segment, and a 134 amino acid cytoplasmic domain. FGFR1 expressed in various tissues, preferentially in cartilaginous tissues and pancreas. It highly expressed in the liver, kidney, heart, brain and skeletal muscle, weakly exp...
TMPY-01587 SULT2A1 Protein, Human, Recombinant (His)

hSTa,HST,ST2,ST2A1,STD,DHEAS,ST2A3,sulfotransferase family, ...

Human E. coli
Hydroxysteroid sulfotransferase ( SULT2A1 ) is a key enzyme in the testicular and hepatic metabolism of 5alpha-androstenone, which is a major component of the off-odor and off-flavor in pork known as boar taint. Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar amon...
TMPJ-01282 Serpin B12 Protein, Human, Recombinant (His)

SERPINB12,Serine Protease Inhibitor-clade B12,Serpin B12

Human HEK293 Cells
Serpin B12 is a member of the serpin family. Serpins are the largest and most diverse family of serine protease inhibitors. Most serpins are secreted and attain physiologic concentrations in the blood and extracellular fluids. Serpin B12 is expressed in many tissues, including brain, bone marrow, lymph node, heart, lung, liver, pancreas, testis, ovary, and intestine. Serpins are involved in a number of fundamental biological processes such as blood coagulation, complement activation, fibrinolysi...
TMPY-01718 Serpin B12 Protein, Mouse, Recombinant (His)

2300003F07Rik,4833409F13Rik,serpin peptidase inhibitor, clad...

Mouse Baculovirus Insect Cells
Serpins are the largest and most diverse family of serine protease inhibitors which are involved in some fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesis, inflammation and tumor suppression and are expressed in a cell-specific manner. Most serpins are secreted and attain physiologic concentrations in the blood and extracellular fluids. Mouse SerpinB12 is a cytoplasm protein that belongs to the serpin family and Ov-serpin subfamily. It ...
TMPJ-01292 Chemerin/RARRES2 Protein, Human, Recombinant (His)

RAR-responsive protein TIG2,RARRES2,Chemerin,Tazarotene-indu...

Human HEK293 Cells
Retinoic acid receptor responder protein 2(RARRES2) is a secreted protein that in humans is encoded by the RARRES2 gene. It is highly expressed in skin, also found in pancreas, liver, spleen, prostate, ovary, small intestine and colon. It is a chemoattractant protein that acts as a ligand for the G protein-coupled receptor CMKLR1. RARRES2 is secreted in an inactive form as prochemerin and is activated through cleavage of the C-terminus by inflammatory and coagulation serine proteases. It is thou...
TMPY-02452 CMBL Protein, Human, Recombinant (His)

carboxymethylenebutenolidase homolog (Pseudomonas),JS-1

Human E. coli
Carboxymethylenebutenolidase (CMBL), also known as 4-carboxymethylenebut-2-en-4-olide lactonohydrolase, maleylacetate enol- lactonase, dienelactone hydrolase, and carboxymethylene butenolide hydrolase, is a hydrolase specially belonging to the family of hydrolases. It maily acts on carboxylic ester bonds. CMBL is a human homolog of Pseudomonas dienelactone hydrolase involved in the bacterial halocatechol degradation pathway. The ubiquitous expression of human CMBL gene transcript in various tiss...
TMPJ-00693 EDF1 Protein, Human, Recombinant (His)

Multiprotein-Bridging Factor 1,EDF-1,Endothelial Differentia...

Human E. coli
Endothelial Differentiation-Related Factor 1 (EDF1) is a 148 amino acid transcriptional coactivator that contains 1 HTH cro/C1-type DNA-binding domain. It has been postulated that the protein functions as a bridging molecule that interconnects regulatory proteins and the basal transcriptional machinery, thereby modulating the transcription of genes involved in endothelial differentiation. When endothelial cells are induced to differentiate in vitro, EDF1 is downregulated, leading to inhibition o...
TMPY-02978 ABHD14B Protein, Human, Recombinant (His)

CIB,abhydrolase domain containing 14B,HEL-S-299

Human E. coli
ABHD14B belongs to the AB hydrolase superfamily, ABHD14 family. It can be detected in spleen, thymus, prostate, testis, ovary, small intestine, colon, peripheral blood leukocyte, heart, placenta, lung, liver, skeletal muscle, pancreas and kidney. ABHD14B has hydrolase activity towards p-nitrophenyl butyrate (in vitro) and may interact with TAF1. It may activate transcription. Recombinant human ABHD14B protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventi...
TMPY-01563 PMP2 Protein, Human, Recombinant (His)

MP2,FABP8,peripheral myelin protein 2,P2,M-FABP

Human E. coli
Myelin P2 protein, also known as PMP2, is a cytosolic protein found primarily in peripheral nerves. It Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. PMP2 is a small, basic, and cytoplasmic lipid binding protein of peripheral myelin. It is similar in amino acid sequence and tertiary structure to fatty acid binding proteins found in the liver, adipocytes, and intestine, its expression is limited to the nervous system. PMP2 is detected only in myelin-producing cells ...
TMPY-03222 PNLIP Protein, Human, Recombinant (His)

PL,pancreatic lipase,PTL,PNLIPD

Human HEK293 Cells
PNLIP is an enzyme that belongs to the lipase family. Secreted from the pancreas, PNLIP is the primary lipase that hydrolyzes dietary fat molecules in the human digestive system, converting triglyceride substrates found in ingested oils to monoglycerides and free fatty acids. Bile salts secreted from the liver and stored in gallbladder are released into the duodenum where they coat and emulsify large fat droplets into smaller droplets, thus increasing the overall surface area of the fat, which a...
TMPY-02883 C1D Protein, Human, Recombinant (GST)

SUNCOR,Rrp47,SUN-CoR,hC1D,C1D nuclear receptor corepressor,L...

Human E. coli
C1D nuclear receptor corepressor belongs to the C1D family. It is a DNA binding and apoptosis-inducing protein.C1D nuclear receptor corepressorinteracts with TSNAX and DNA-PKcs. It acts as a corepressor for the thyroid hormone receptor. It is thought that C1D nuclear receptor corepressor regulates TRAX/Translin complex formation. It is expressed in kidney, heart, brain, spleen, lung, testis, liver and small intestine. It plays a role in the recruitment of the RNA exosome complex to pre-rRNA to m...
TMPY-02163 PGLYRP1 Protein, Mouse, Recombinant (His)

Tnfsf3l,peptidoglycan recognition protein 1,PGRP,Tasg7,Tag7,...

Mouse HEK293 Cells
Peptidoglycan recognition protein 1, also known as Peptidoglycan recognition protein short, PGRP-S, PGLYRP1, PGLYRP, PGRP and TNFSF3L, is a secreted protein that belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. PGLYRP1 / PGLYRP is highly expressed in bone marrow. It is weakly expressed in kidney, liver, small intestine, spleen, thymus, peripheral leukocyte, lung, fetal spleen and neutrophils. PGLYRP1 / PGLYRP is a pattern receptor that binds to murein peptidoglycans (PGN) of Gram-posi...
TMPY-00963 ASAH2 Protein, Mouse, Recombinant (His)

N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) ...

Mouse HEK293 Cells
ASAH2 (N-acylsphingosine amidohydrolase 2), also known as neutral ceramidase, is a type II integral membrane protein that can be cleaved to produce a soluble secreted protein. The enzyme is abundant in the brush border membranes of the intestine, and also expressed in several tissues such as kidney, brain and liver. The primary structure of ASAH2/neutral ceramidase is highly conserved from bacteria to humans, however, there is a clear difference in the molecular architecture. The murine ASAH2 po...
TMPJ-00058 BTC Protein, Mouse, Recombinant (His)

βcellulin,isoform CRA_a,Btc,Betacellulin,mCG_12529

Mouse E. coli
Mouse Betacellulin is a single type I membrane protein which belongs to the EGF family of cytokines. EGF family has many members including EGF, TGF-a, Amphiregulin, HB-EGF, Epiregulin, Tomoregulin and the Neuregulins. Betacellulin is characterised by a six-cysteine consensus motif that forms three intra-molecular disulfide bonds crucial for binding the ErbB receptor family. Betacellulin is expressed in several tissues and tumor cells including kidney, uterus, liver, pancreas and small intestine....
TMPY-01879 S100A14 Protein, Human, Recombinant (His)

S100 calcium binding protein A14,BCMP84,S100A15

Human E. coli
S100 protein is a family of low molecular weight protein found in vertebrates characterized by two EF-hand calcium-binding motifs. There are at least 21 different S100 proteins, and the name is derived from the fact that the protein is 100% soluble in ammonium sulfate at neutral pH. Most S100 proteins are disulfide-linked homodimer, and is normally present in cells derived from theneural crest, chondrocytes, macrophages, dendritic cells, etc. S100 proteins have been implicated in a variety of in...
TMPY-01617 SULT1B1 Protein, Human, Recombinant (His)

sulfotransferase family, cytosolic, 1B, member 1,SULT1B2,ST1...

Human E. coli
Sulfotransferase family cytosolic 1B member 1, also known as Sulfotransferase 1B1, Sulfotransferase 1B2, Thyroid hormone sulfotransferase, SULT1B1 and ST1B2, is a cytoplasm protein that belongs to the sulfotransferase 1 family. Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. SULT1B1 is highly expressed in the liver, perip...
TMPY-01595 PCBP1 Protein, Human, Recombinant (His)

HNRPE1,hnRNP-E1,HEL-S-85,HNRPX,poly(rC) binding protein 1,hn...

Human E. coli
Poly(rC)-binding protein 1, also known as Heterogeneous nuclear ribonucleoprotein E1, Alpha-CP1, Nucleic acid-binding protein SUB2.3 and PCBP1, is a family member of heterogeneous nuclear ribonucleoproteins (hnRNPs) that belong to RNA-binding proteins and bear three KH domains. PCBP1 is loosely bound in the nucleus. It may shuttle between the nucleus and the cytoplasm. It is abundantly expressed in skeletal muscle, thymus and peripheral blood leukocytes while a lower expression is observed in pr...
TMPY-02948 SULT1A3 Protein, Human, Recombinant (His)

M-PST,HAST,SULT1A3,ST1A3/ST1A4,HAST3,SULT1A4,TL-PST,STM,sulf...

Human E. coli
SULT1A3 belongs to the sulfotransferase 1 family. Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. They are different in their tissue distributions and substrate specificities while their gene structure (number and length of exons) is similar. SULT1A3 gene encodes a phenol sulfotransferase with thermolabile enzyme activity. Four sulfotransferase genes are located on the p arm of chromosome 16; this gene and SULT1A4 ar...
TMPY-02181 PLA2G12B Protein, Mouse, Recombinant (His)

Fksg71,2010002E04Rik,Pla2g13,hlb218,phospholipase A2, group ...

Mouse HEK293 Cells
Group XIIB secretory phospholipase A2-like protein, also known as Group XIII secretory phospholipase A2-like protein, GXIII sPLA2-like, sPLA2-GXIIB, GXIIB, PLA2G13 and PLA2G12B, is a secreted protein that belongs to the phospholipase A2 family. PLA2G12B / PLA2G13 is strongly expressed in liver, small intestine and kidney. Mammalian secretory phospholipase A2s ( sPLA2s ) form a family of structurally related enzymes that are involved in a variety of physiological and pathological processes via th...
TMPY-04567 SRPK1 Protein, Human, Recombinant (His & GST)

SRSF protein kinase 1,SFRSK1,RP3-422H11.1

Human Baculovirus Insect Cells
Serine / threonine-protein kinase SRPK1, also known as SFRS protein kinase 1, Serine/arginine-rich protein-specific kinase 1, SR-protein-specific kinase 1 and SRPK1, is a cytoplasm and nucleus protein that belongs to the protein kinase superfamily and CMGC Ser/Thr protein kinase family. Isoform 2 of SRPK1 is predominantly expressed in the testis but is also present at lower levels in heart, ovary, small intestine, liver, kidney, pancreas and skeletal muscle. Isoform 1 of SRPK1 is only seen in th...
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重组蛋白

Cadherin 17/CDH17 Protein, Rat, Recombinant (His)
Cat.No: TMPY-02919
Species: Rat
Expression System: HEK293 Cells
Cadherin 17/CDH17 Protein, Cynomolgus, Recombinant (hFc)
Cat.No: TMPY-05352
Species: Cynomolgus
Expression System: HEK293 Cells
Cadherin 17/CDH17 Protein, Human, Recombinant (His)
Cat.No: TMPY-01912
Species: Human
Expression System: HEK293 Cells
Cadherin 17/CDH17 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPY-06645
Species: Cynomolgus
Expression System: HEK293 Cells
Cadherin 17/CDH17 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-06324
Species: Human
Expression System: HEK293 Cells
CDH17 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00583
Species: Human
Expression System: HEK293 Cells
Intrinsic Factor Protein, Human, Recombinant (His)
Cat.No: TMPY-03221
Species: Human
Expression System: HEK293 Cells
CXCL11 Protein, Human, Recombinant
Cat.No: TMPY-03274
Species: Human
Expression System: E. coli
RANKL/TNFSF11/CD254 Protein, Human, Recombinant (E. coli)
Cat.No: TMPJ-00662
Species: Human
Expression System: E. coli
Serpin F2 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPJ-00302
Species: Mouse
Expression System: HEK293 Cells
CDH17 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00947
Species: Human
Expression System: HEK293 Cells
CDH17 Domain 3 & 4 Protein, Human, Recombinant (mFc)
Cat.No: TMPK-00952
Species: Human
Expression System: HEK293 Cells
GBA3 Protein, Human, Recombinant (His)
Cat.No: TMPY-01579
Species: Human
Expression System: Baculovirus Insect Cells
CDH17 Protein (Primary Amine Labeling), Mouse, Recombinant (His), Biotinylated
Cat.No: TMPK-01224
Species: Mouse
Expression System: HEK293 Cells
CDH17 Domain 7 Protein, Human, Recombinant (hFc)
Cat.No: TMPK-00949
Species: Human
Expression System: HEK293 Cells
CBR3 Protein, Human, Recombinant (His)
Cat.No: TMPY-03867
Species: Human
Expression System: E. coli
Apolipoprotein A-V/APOA5 Protein, Mouse, Recombinant (His)
Cat.No: TMPK-01087
Species: Mouse
Expression System: E. coli
AKR1C3 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00962
Species: Human
Expression System: HEK293 Cells
CDH17 Domain 6-7 Protein, Human, Recombinant (hFc)
Cat.No: TMPK-00950
Species: Human
Expression System: HEK293 Cells
CDH17 Protein, Rhesus macaque, Recombinant (His)
Cat.No: TMPK-00473
Species: Rhesus
Expression System: HEK293 Cells
CDH17 Protein, Mouse, Recombinant (His)
Cat.No: TMPK-01223
Species: Mouse
Expression System: HEK293 Cells
CDH17 Protein, Human, Recombinant (hFc)
Cat.No: TMPK-00948
Species: Human
Expression System: HEK293 Cells
CDH17 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-00555
Species: Cynomolgus
Expression System: HEK293 Cells
CDH17 Domain 6-7 Protein, Human, Recombinant (mFc)
Cat.No: TMPK-00953
Species: Human
Expression System: HEK293 Cells
GPT Protein, Rat, Recombinant (His)
Cat.No: TMPY-01099
Species: Rat
Expression System: Baculovirus Insect Cells
RGS5 Protein, Human, Recombinant (His)
Cat.No: TMPY-04058
Species: Human
Expression System: E. coli
RANK/TNFRSF11A Protein, Human, Recombinant (aa 30-212, His)
Cat.No: TMPJ-00349
Species: Human
Expression System: HEK293 Cells
BPHL Protein, Human, Recombinant (His)
Cat.No: TMPY-03330
Species: Human
Expression System: E. coli
CDH17 Domain 5-7 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated
Cat.No: TMPK-00951
Species: Human
Expression System: HEK293 Cells
GPT2 Protein, Rat, Recombinant (His)
Cat.No: TMPY-01100
Species: Rat
Expression System: Baculovirus Insect Cells
FGFRL1 Protein, Human, Recombinant (His)
Cat.No: TMPJ-01224
Species: Human
Expression System: HEK293 Cells
SULT2A1 Protein, Human, Recombinant (His)
Cat.No: TMPY-01587
Species: Human
Expression System: E. coli
Serpin B12 Protein, Human, Recombinant (His)
Cat.No: TMPJ-01282
Species: Human
Expression System: HEK293 Cells
Serpin B12 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01718
Species: Mouse
Expression System: Baculovirus Insect Cells
Chemerin/RARRES2 Protein, Human, Recombinant (His)
Cat.No: TMPJ-01292
Species: Human
Expression System: HEK293 Cells
CMBL Protein, Human, Recombinant (His)
Cat.No: TMPY-02452
Species: Human
Expression System: E. coli
EDF1 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00693
Species: Human
Expression System: E. coli
ABHD14B Protein, Human, Recombinant (His)
Cat.No: TMPY-02978
Species: Human
Expression System: E. coli
PMP2 Protein, Human, Recombinant (His)
Cat.No: TMPY-01563
Species: Human
Expression System: E. coli
PNLIP Protein, Human, Recombinant (His)
Cat.No: TMPY-03222
Species: Human
Expression System: HEK293 Cells
C1D Protein, Human, Recombinant (GST)
Cat.No: TMPY-02883
Species: Human
Expression System: E. coli
PGLYRP1 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-02163
Species: Mouse
Expression System: HEK293 Cells
ASAH2 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-00963
Species: Mouse
Expression System: HEK293 Cells
BTC Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-00058
Species: Mouse
Expression System: E. coli
S100A14 Protein, Human, Recombinant (His)
Cat.No: TMPY-01879
Species: Human
Expression System: E. coli
SULT1B1 Protein, Human, Recombinant (His)
Cat.No: TMPY-01617
Species: Human
Expression System: E. coli
PCBP1 Protein, Human, Recombinant (His)
Cat.No: TMPY-01595
Species: Human
Expression System: E. coli
SULT1A3 Protein, Human, Recombinant (His)
Cat.No: TMPY-02948
Species: Human
Expression System: E. coli
PLA2G12B Protein, Mouse, Recombinant (His)
Cat.No: TMPY-02181
Species: Mouse
Expression System: HEK293 Cells
SRPK1 Protein, Human, Recombinant (His & GST)
Cat.No: TMPY-04567
Species: Human
Expression System: Baculovirus Insect Cells
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