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Search Results for " kallikrein "

36

抑制剂 & 化合物

38

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T73611	Kallikrein
	Kallikrein 能够在血浆和组织中形成激肽释放酶激肽系统（KKS)，分别产生缓激肽和激肽肽。
T40312	Plasma kallikrein-IN-1
	Plasma kallikrein-IN-1 is a PKK inhibitor with an IC 50 value of 0.5 nM.
T63579	Kallikrein-IN-1
	Kallikrein-IN-1 (Formula A) 是一种激肽释放酶 Kallikrein 抑制剂。
T63796	Kallikrein-IN-2
	Kallikrein-IN-2 (compound 1) 是一种激肽释放酶 Kallikrein 的抑制剂。
T72337	Plasma kallikrein-IN-2
	Plasma kallikrein-IN-2 是一个有效的 plasma kallikrein (PKal)抑制剂，IC50值为 0.1 nM。Plasma kallikrein-IN-2 可用于遗传性血管水肿、糖尿病性黄斑水肿、糖尿病视网膜病变的研究。
T72624	Kallikrein 5-IN-2
	Kallikrein 5-IN-2 是一种选择性 KallikreinKLK5抑制剂 (pIC50=7.1)。KLK5 抑制可以使表皮脱落正常化并减少相关的炎症和瘙痒。
T61403	Plasma kallikrein-IN-3
	Plasma kallikrein-IN-3, a potent inhibitor ( IC 50 : 0.15 μM) of plasma kallikrein, finds application in research related to hereditary angioedema, diabetic macular edema, and diabetic retinopathy [1].
T11885	LSP-249	Others	Others
	LSP-249是血浆 kallikrein 的抑制剂，用于血管性水肿的研究，EC50值小于 100 nM。
T14358	Avoralstat BCX4161	Others	Others
	Avoralstat (BCX4161) 是血浆激肽释放酶(PKK)抑制剂，具有口服活性，可用于遗传性血管性水肿的研究。
T3359	Aprotinin 抑酶肽,抑肽酶,Bovine Pancreatic Trypsin Inhibitor,Traskolan,Antilysin	Others; Serine Protease; Influenza Virus; Proteasome	Microbiology/Virology; Others; Proteases/Proteasome; Ubiquitination
	Aprotinin (Traskolan) 是分离自牛肺的一种广谱丝氨酸蛋白酶抑制剂，可抑制多种不同酯酶和蛋白酶的活性。
T6370	AEBSF hydrochloride AEBSF HCl,Pefabloc SC	Thrombin; Serine Protease; Influenza Virus	Microbiology/Virology; Proteases/Proteasome
	AEBSF hydrochloride (Pefabloc SC) 是一种丝氨酸蛋白酶的不可逆抑制剂。
T39350	Sebetralstat KVD900	Others	Others
	Sebetralstat (KVD900) 是一种血浆激肽释放酶抑制剂，可用于代谢性疾病的研究。
TP1792L	KKI-5 acetate(97145-43-2 free base)	Serine Protease	Proteases/Proteasome
	KKI-5 acetate(97145-43-2 free base) 是一种丝氨酸蛋白酶抑制剂，可抑制激肽释放酶和纤溶酶。 KKI 5 可能表现出抗癌化疗益处，也可用作血管性水肿的治疗方法。
T68173	ZD-2138 Ici-D2138	Lipoxygenase	Metabolism
	ZD-2138是一种有效且具有选择性的5-脂氧合酶（5-LOX）的特异性抑制剂，抑制了过敏原诱导的肺支气管收缩，可减少豚鼠孤立气道的神经诱发性快速激肽能收缩。ZD-2138可用来治疗哮喘疾病。
T0372	Gabexate mesylate 甲磺酸加贝酯,FOY	Factor Xa; Serine Protease; Proteasome	Metabolism; Proteases/Proteasome; Ubiquitination
	Gabexate mesylate (FOY) 是一种非抗原的类胰蛋白酶丝氨酸蛋白酶抑制剂。
T21610	Bradykinin (acetate)	Bradykinin Receptor	GPCR/G Protein
	Bradykinin (acetate) 是一种由激肽释放酶-激肽系统产生的活性肽。它是一种炎症介质，也被认为是多种血管和肾功能的神经介质和调节剂。它由血液中的 kallidin 酶促产生，是一种强大的血管扩张剂，可引起平滑肌收缩，并可能介导炎症。它具有作为人血清代谢物和血管扩张剂的作用。它是缓激肽 (2+) 的互变异构体。
T70161	Berotralstat HCl
	Berotralstat HCl is a novel selective inhibitor of plasma kallikrein, blocking the enzymatic activity of plasma kallikrein in releasing bradykinin, the major biologic peptide that promotes swelling and pain associated with attacks of HAE.
T37033	H-D-Pro-Phe-Arg-pNA . 2 HCl
	pFR-pNA, chromogenic substrate for the determination of plasma kallikrein-like activity. CAS Number (net): 64816-19-9.
T82510	Ecallantide TFA DX-88 TFA
	Ecallantide (DX-88) TFA 是一种特异性的重组血浆激肽释放酶(Kallikrein)抑制剂，作用于缓激肽的生成过程以减少其产生。此化合物主要用于预防和治疗血管性水肿的急性攻击。
T71417	LM-030
	LM-030, also known as BPR277, is a novel inhibitor of kallikrein-related peptidase 7 (KLK7) and epidermal elastase 2 (ELA2).
T80271	Irucalantide
	Irucalantide 是一种激肽释放酶（kallikrein）抑制剂，能够阻碍这种酶的活性，从而影响相关的生物过程。
T35579	PKSI-527
	PKSI-527 is an inhibitor of plasma kallikrein (Ki = 0.81 μM). It is selective for plasma kallikrein over glandular kallikrein, plasmin, thrombin, urokinase, and Factor Xa (Kis = >500, 390, >500, 200, and >500 μM, respectively). PKSI-527 reduces bradykinin generation induced by kaolin and λ-carrageenan ex vivo in human plasma. It also prolongs partial thromboplastin and euglobulin clot lysis times. In vivo, PKSI-527 (300 mg/kg per day) reduces hyperplasia, pannus formation, and infiltration of in...
T77999	KKI-5 TFA
	KKI-5 (TFA)为特异性组织激肽释放酶抑制剂，能有效减少乳腺癌细胞的浸润性。
T63507	Feniralstat
	Feniralstat 是吡唑衍生物，是一种激肽释放酶 (kallikrein) 的有效抑制剂，能够抑制人血浆激肽释放酶 (pKal) (IC50: 6.7 nM)。Feniralstat 不抑制人 KLK1、人 FXIa 和人因子 Xlla (IC50均 >40 μM)。
TP1379	KKI-5 TFA(97145-43-2 free base) KKI-5 (TFA)
	KKI-5 (TFA) is a specific tissue kallikrein inhibitor.Kki-5 (TFA) can reduce breast cancer cell infiltration.
T35869	Berotralstat
	Berotralstat (BCX7353) is a second-generation, synthetic, and orally active plasma kallikrein inhibitor with low toxicity. It is highly specific and effectively used in the research of hereditary angioedema (HAE) attacks. Berotralstat functions by inhibiting the enzymatic activity of plasma kallikrein, which is responsible for the release of bradykinin. This blocking mechanism targets the major biologic peptide involved in the promotion of swelling and pain associated with HAE attacks[1][2].
TP1013	N-CBZ-Phe-Arg-AMC Z-FR-AMC
	N-CBZ-Phe-Arg-AMC (Z-FR-AMC) is a substrate for serine proteases, including cathepsins, kallikrein and plasmin. Absorption/emission of substrate = 330/390 nm (weak fluorescence); absorption/emission of end product (AMC) = 342/441 nm (strong fluorescence).
T80095	D-Pro-Phe-Arg-Chloromethylketone	Factor Xa	Metabolism
	D-Pro-Phe-Arg-Chloromethylketone是一种抑制剂，它针对凝血因子XII (coagulation factor XII) 和血浆激肽释放酶 (kallikrein)，在血栓形成和炎症过程中具有关键作用。
T69777	DKFZ-251
	DKFZ-251 is a potent inhibitor of kallikrein-related peptidase 6 with on-target cellular activity. DKFZ-251 demonstrated good selectivity for KLK6 compared to other KLKs, and on-target activity in a cellular assay.
T78572	Ecallantide DX-88
	Ecallantide (DX-88) 是高特异性重组血浆激肽释放酶抑制剂，用于阻断缓激肽生成，治疗血管性水肿急性发作。
TP1792	KKI-5
	KKI 5 is a serine protease inhibitor that inhibits kallikrein and plasmin. KKI 5 may exhibit anticancer chemotherapeutic benefit and may also be used as a treatment for angioedema.
T6564L	Leupeptin Leupeptin Ac-LL,NK-381
	Leupeptin is a competitive protease inhibitor produced by actinomycetes. Leupeptin can inhibit cysteine, serine and threonine peptidases. Leupeptin inhibits serine proteinases (trypsin (Ki=3.5 nM), plasmin (Ki= 3.4 nM), porcine kallikrein), and cysteine p
T69297	Leupeptin HCl
	Leupeptin is a naturally occurring protease inhibitor that can inhibit cysteine, serine and threonine peptidases. Leupeptin is an organic compound produced by actinomycetes. Leupeptin inhibits serine proteinases (trypsin (Ki=3.5 nM), plasmin (Ki= 3.4 nM), porcine kallikrein), and cysteine proteinases (papain, cathepsin B (Ki = 4.1 nM), endoproteinase Lys-C). It does not inhibit α-chymotrypsin or thrombin. Leupeptin is a competitive transition state inhibitor and its inhibition may be relieved by...
T76248	Tutuilamide A
	Tutuilamide A为一有效抑制剂，针对猪胰弹性蛋白酶(PPE)展现出1.2 nM的IC50值。此外，该化合物亦对人中性粒细胞弹性蛋白酶(HNE; IC50=0.73 nM)及激肽释放酶7(KLK7; IC50=5.0 nM)有抑制作用。
T76710	Lanadelumab
	Lanadelumab (SHP643) 是一种针对血浆激肽释放酶 (plasma kallikrein (pKal)) 的人源化IgG1单克隆抗体，Ki 值为 0.12 nM。Lanadelumab 抑制游离和 HMWK 结合的 pKal。Lanadelumab 具有研究遗传性血管性水肿的潜力
T70170	Milvexian TFA
	Milvexian, also known as BMS-986177 and JNJ-70033093, is a blood coagulation factor XIa inhibitor. Milvexian demonstrated good selectivity over plasma kallikreinKi = 44 nM (400-fold selective), and chymotrypsinKi = 35 nM (318-fold selective). At a dose of 1.5 mg/kg, Milvexian exhibited an overall exposure of 1215 nM/h, low clearance of 10.3 mL/min/kg, and oral bioavailability of 32%.

化合物

Cat.No: T73611

Plasma kallikrein-IN-1

Cat.No: T40312

Kallikrein-IN-1

Cat.No: T63579

Kallikrein-IN-2

Cat.No: T63796

Plasma kallikrein-IN-2

Cat.No: T72337

Kallikrein 5-IN-2

Cat.No: T72624

Plasma kallikrein-IN-3

Cat.No: T61403

Cat.No: T11885

Target: Others

Cat.No: T14358

Synonym: BCX4161

Target: Others

Cat.No: T3359

Synonym: 抑酶肽,抑肽酶,Bovine Pancreatic Trypsin Inhibitor,Traskolan,Antilysin

Target: Others, Serine Protease, Influenza Virus, Proteasome

AEBSF hydrochloride

Cat.No: T6370

Synonym: AEBSF HCl,Pefabloc SC

Target: Thrombin, Serine Protease, Influenza Virus

Cat.No: T39350

Synonym: KVD900

Target: Others

KKI-5 acetate(97145-43-2 free base)

Cat.No: TP1792L

Target: Serine Protease

Cat.No: T68173

Synonym: Ici-D2138

Target: Lipoxygenase

Gabexate mesylate

Cat.No: T0372

Synonym: 甲磺酸加贝酯,FOY

Target: Factor Xa, Serine Protease, Proteasome

Bradykinin (acetate)

Cat.No: T21610

Target: Bradykinin Receptor

Berotralstat HCl

Cat.No: T70161

H-D-Pro-Phe-Arg-pNA . 2 HCl

Cat.No: T37033

Ecallantide TFA

Cat.No: T82510

Synonym: DX-88 TFA

Cat.No: T71417

Cat.No: T80271

Cat.No: T35579

Cat.No: T77999

Cat.No: T63507

KKI-5 TFA(97145-43-2 free base)

Cat.No: TP1379

Synonym: KKI-5 (TFA)

Cat.No: T35869

N-CBZ-Phe-Arg-AMC

Cat.No: TP1013

Synonym: Z-FR-AMC

D-Pro-Phe-Arg-Chloromethylketone

Cat.No: T80095

Target: Factor Xa

Cat.No: T69777

Cat.No: T78572

Synonym: DX-88

Cat.No: TP1792

Cat.No: T6564L

Synonym: Leupeptin Ac-LL,NK-381

Cat.No: T69297

Cat.No: T76248

Cat.No: T76710

Cat.No: T70170

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPJ-01405	Kallikrein 5/KLK5 Protein, Human, Recombinant (His) Stratum Corneum Tryptic Enzyme,Kallikrein-Like Prot...	Human	HEK293 Cells
	Kallikrein 5/KLK5 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 40 KDa and the accession number is Q9Y337.
TMPY-02258	Kallikrein 3/KLK3 Protein, Human, Recombinant (His) APS,KLK2A1,PSA,kallikrein related peptidase 3,Hk3	Human	HEK293 Cells
	KLK3 (Kallikrein Related Peptidase 3) is a Protein Coding gene. The gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. It encodes a single-chain glycoprotein, a protease that is synthesized in the epithelial cells of the prostate gland and is present in seminal plasma. KLK3, also known as Prostate Specific Antigen (PSA), kallikrein-related peptidase 3, Gamma-seminoprotein, is a secreted protein of the glandular kallikrein subfamily of serine proteases....
TMPJ-00891	Kallikrein 2/KLK2 Protein, Human, Recombinant (His) hGK-1,Kallikrein-2,Tissue Kallikrein-2,KLK...	Human	HEK293 Cells
	Kallikrein-2 (KLK2) is a secreted serine protease that belongs to the peptidase S1 family of Kallikrein subfamily. KLK2 contains 1 peptidase S1 domain. It is highly expressed in the human prostate gland. KLK2 can cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin, but Preferential cleavages of Arg-\|-Xaa bonds in small molecule substrates. It also highly selective action to release kallidin (lysyl-bradykinin) from kininogen involves hydrolysis of Met-\|-Xaa or Leu-\|-Xaa. KLK2 ...
TMPY-05289	Kallikrein 15/KLK15 Protein, Human, Recombinant (His) ACO,HSRNASPH,kallikrein-related peptidase 15	Human	HEK293 Cells
	Kallikrein 15/KLK15 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.8 kDa and the accession number is Q9H2R5-1.
TMPY-00866	Kallikrein 1/KLK1 Protein, Human, Recombinant (His) KLKR,kallikrein 1,hK1,Klk6	Human	HEK293 Cells
	Kallikrein 1/KLK1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28 kDa and the accession number is A0A1R3UCD2.
TMPJ-00475	Kallikrein 1/KLK1 Protein, Human, Recombinant (aa 19-262, His) Tissue Kallikrein,Kidney/Pancreas/Salivary Gland	Human	HEK293 Cells
	Kallikrein-1 (KLK1) is a member of human tissue Kallikrein family. Human KLK1 precursor contains a singal peptide (residues 1 to 18), a short pro peptide (residues 19 to 24) and a mature chain (residues 25 to 262). The function of KLK1 is to cleave Kininogen in order to release the vasoactive Kinin peptide (Lysyl-Bradykinin or Bradykinin). The Kinin peptide controls blood pressure reduction, vasodilation, smooth muscle relaxation and contraction, pain induction and inflammation. KLK1 also plays ...
TMPY-04032	Kallikrein 1/KLK1 Protein, Mouse, Recombinant (His) Kal,mGk-6,Klk1b6,kallikrein 1,Klk6,0610007D04Rik	Mouse	HEK293 Cells
	Kallikrein 1/KLK1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28.3 kDa and the accession number is P15947.
TMPY-00491	Kallikrein 15/KLK15 Protein, Human, Recombinant (hFc) ACO,kallikrein-related peptidase 15,HSRNASPH	Human	HEK293 Cells
	Kallikrein 15/KLK15 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 53.1 kDa and the accession number is Q9H2R5-1.
TMPY-03017	Kallikrein 7/KLK7 Protein, Mouse, Recombinant (His) Prss6,SCCE,kallikrein-related peptidase 7	Mouse	HEK293 Cells
	Kallikrein 7/KLK7 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.5 kDa and the accession number is Q91VE3.
TMPY-01900	Kallikrein 4/KLK4 Protein, Human, Recombinant (His) PSTS,kallikrein,kallikrein-related peptida...	Human	HEK293 Cells
	Kallikrein-4, also known as Enamel matrix serine proteinase 1, Kallikrein-like protein 1, KLK-L1, Serine protease 17, KLK4, PRSS17, and EMSP1, is a secreted protein that belongs to the peptidase S1 family and Kallikrein subfamily. Kallikrein-4 / KLK4 is a serine protease expressed during enamel maturation, and proteolytic processing of the enamel matrix by KLK4 is critical for proper enamel formation. Kallikrein-4 / KLK4 contains one peptidase S1 domain. Kallikrein-4 / KLK4 is secreted by transi...
TMPY-06608	Kallikrein 15/KLK15 Protein, Mouse, Recombinant (His) kallikrein-related peptidase 15	Mouse	HEK293 Cells
	Kallikrein 15/KLK15 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.96 kDa and the accession number is NP_777354.1.
TMPK-00766	KLKB1 Protein, Human, Recombinant (His) PKK,Kininogenin,KLK3,KLKB1,Fletcher factor,Plasma kallik...	Human	HEK293 Cells
	Plasma kallikrein, also known as Fletcher factor or kallikrein B1 (KLKB1), is a serine endopeptidase, like its homologs tissue kallikrein and kallikrein-related peptidases (KLKs). Its physiological role is to catalyze the release of kinins and other vasoactive peptides. KLKB1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 70.3 kDa and the accession number is P03952.
TMPY-02786	Kallikrein 11/KLK11 Protein, Mouse, Recombinant (His) 2310015I08Rik,TLSP,kallikrein-related peptidase 11,...	Mouse	HEK293 Cells
	Kallikrein 11/KLK11 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.3 kDa and the accession number is Q9QYN3.
TMPK-01158	Kallikrein 5/KLK5 Protein, Mouse, Recombinant (His) SCTE,KLKL2,KLK5,KLK-L2,Klnc,Kallikrein c	Mouse	HEK293 Cells
	The inhibition of kallikrein 5 (KLK5) has been identified as a potential strategy for treatment of the genetic skin disorder Netherton syndrome, in which loss-of-function mutations in the SPINK5 gene lead to down-regulation of the endogenous inhibitor LEKTI-1 and profound skin-barrier defects with severe allergic manifestations. To aid in the development of a medicine for this target, an X-ray crystallographic system was developed to facilitate fragment-guided chemistry and knowledge-based drug-...
TMPY-01417	Kallikrein 7/KLK7 Protein, Human, Recombinant (His) kallikrein-related peptidase 7,hK7,SCCE,PRSS6	Human	HEK293 Cells
	Kallikrein 7/KLK7 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.7 kDa and the accession number is A0A024R4H6.
TMPY-00867	Kallikrein 13/KLK13 Protein, Human, Recombinant (His) KLKL4,kallikrein-related peptidase 13,KLK-L4	Human	HEK293 Cells
	Tissue kallikrein 13 (hK13), also known as KLK-L4 (kallikrein-like gene 4), is a member of the human tissue kallikrein family of serine proteases having diverse physiological functions in many tissues. The KLK13 gene resides on chromosome 19q13.3-4 along with other 14 members in a gene cluster and shares a high degree of homology. KLK13 is a trypsin-like, secreted serine protease expressed specifically in the testicular tissue including prostate, salivary gland, breast, and testis. Growing evide...
TMPY-01105	Kallikrein 11/KLK11 Protein, Human, Recombinant (His) TLSP,KLK11,kallikrein-related peptidase 11,PRSS20	Human	HEK293 Cells
	Kallikrein 11/KLK11 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27 kDa and the accession number is A0A1R3UDR5.
TMPY-02759	Kallikrein 6/KLK6 Protein, Human, Recombinant (His) kallikrein-related peptidase 6,PRSS18,PRSS9,Klk7,Bs...	Human	HEK293 Cells
	KLK6 (kallikrein-related peptidase 6), also known as Klk7, belongs to the peptidase S1 family, Kallikrein subfamily. Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. KLK6 is a serine protease that exhibits a preference for Arg over Lys in the substrate P1 position and for Ser or Pro in the P2 position. Klk7 sh...
TMPY-01992	Kallikrein 8/KLK8 Protein, Human, Recombinant (His) kallikrein-related peptidase 8,PRSS19,TADG14,NRPN,N...	Human	HEK293 Cells
	Kallikrein-8, also known as Neuropsin, Serine protease 19, Serine protease TADG-14, Tumor-associated differentially expressed gene 14 protein, and KLK8 is a secreted protein that belongs to the peptidase S1 family and Kallikrein subfamily. It is a serine protease that is capable of degrading some proteins such as casein, fibrinogen, kininogen, fibronectin, and collagen type IV. Kallikrein-8 / KLK8 plays a role in the formation and maturation of orphan and small synaptic boutons in the Schaffer-c...
TMPJ-00544	Kallikrein 7/KLK7 Protein, Human, Recombinant (aa 23-252, His) PRSS6,Serine Protease 6,hK7,Stratum Corneum Chymotryptic Enz...	Human	HEK293 Cells
	Human Kallikrein 7 is a member of the tissue kallikrein family of extracellular serine proteases that is made up of 15 members. It is predominantly expressed in the skin. A major physiological function of Kallikrein 7 is to regulate the desquamation process (the shedding of corneocytes from the outer layer of the epidermis) through proteolysis of the intercellular adhesive structures between corneocytes. Dysregulation of Kallikrein 7 has been linked to several inflammatory skin diseases includin...
TMPJ-00557	Kallikrein 8/KLK8 Protein, Human, Recombinant (aa 29-260, His) Tumor-Associated Differentially Expressed Gene 14 Protein,TA...	Human	HEK293 Cells
	Kallikrein 8/KLK8 Protein, Human, Recombinant (aa 29-260, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 35 KDa and the accession number is AAH40887.1.
TMPK-00857	KLKB1 Protein, Mouse, Recombinant (His) Kininogenin,KLK3,Fletcher factor,Plasma kallikrein,...	Mouse	HEK293 Cells
	Plasma kallikrein, also known as Fletcher factor or kallikrein B1 (KLKB1), is a serine endopeptidase, like its homologs tissue kallikrein and kallikrein-related peptidases (KLKs). Its physiological role is to catalyze the release of kinins and other vasoactive peptides. KLKB1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 70.3 kDa and the accession number is P26262.
TMPK-00525	KLKB1 Protein, Cynomolgus, Recombinant (His) KLK3,Plasma kallikrein,KLKB1,PKK,Kininogenin,Fletch...	Cynomolgus	HEK293 Cells
	Plasma kallikrein, also known as Fletcher factor or kallikrein B1 (KLKB1), is a serine endopeptidase, like its homologs tissue kallikrein and kallikrein-related peptidases (KLKs). Its physiological role is to catalyze the release of kinins and other vasoactive peptides. KLKB1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 70.19 kDa and the accession number is A0A2K5VTJ9.
TMPJ-00931	Serpin A4 Protein, Human, Recombinant (His) Kallistatin,Peptidase Inhibitor 4,KST,Kallikrein In...	Human	HEK293 Cells
	Serpin Peptidase Inhibitor, Clade A (α-1 Antiproteinase, Antitrypsin), Member 4 (Serpin A4) is a member of the Serpin family. Serpin A4 exists as a monomer and some homodimers. Serpin A4 is expressed by the liver and secreted in plasma. Serpin A4 is a regulator of vascular homeostasis capable of controlling a wide spectrum of biological actions in the cardiovascular and renal systems. It can inhibit intracellular reactive oxygen species formation in cultured cardiac and renal cells. In addition,...
TMPH-01568	Kallikrein-9 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Kallikrein-9 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 49.2 kDa and the accession number is Q9UKQ9.
TMPH-02746	Kallikrein 8 Protein, Mouse, Recombinant (His)	Mouse	P. pastoris (Yeast)
	Kallikrein 8 Protein, Mouse, Recombinant (His) is expressed in Yeast.
TMPH-02744	Kallikrein 14 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Kallikrein 14 Protein, Mouse, Recombinant (His) is expressed in E. coli.
TMPH-03465	Kallikrein 15 Protein, S. cerevisiae, Recombinant (hFc)	Saguinus oedipus	HEK293 Cells
	Protease whose physiological substrate is not yet known. Kallikrein 15 Protein, S. cerevisiae, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 54.8 kDa and the accession number is Q7JIG6.
TMPH-02745	Kallikrein 8 Protein, Mouse, Recombinant (E. coli, His)	Mouse	E. coli
	Kallikrein 8 Protein, Mouse, Recombinant (E. coli, His) is expressed in E. coli.
TMPJ-00468	KLK10 Protein, Human, Recombinant (His) Kallikrein-10,Protease Serine-Like 1,KLK10,NES1,Nor...	Human	HEK293 Cells
	KLK10 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 34 KDa and the accession number is AAH02710.1.
TMPH-00661	Ecotin Protein, E. coli O127:H6, Recombinant (His & Myc) eco,Ecotin	E. coli	E. coli
	General inhibitor of pancreatic serine proteases: inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases.
TMPK-01271	Coagulation factor XI Protein, Cynomolgus, Recombinant (His) F11,PTA,FXI,Coagulation factor XI	Cynomolgus	HEK293 Cells
	Factor XI (FXI) is the zymogen of a plasma protease (FXIa) that contributes to hemostasis by activating factor IX (FIX). In the original cascade model of coagulation, FXI is converted to FXIa by factor XIIa (FXIIa), a component, along with prekallikrein and high-molecular-weight kininogen (HK), of the plasma kallikrein-kinin system (KKS).
TMPJ-00481	CELA3A Protein, Human, Recombinant (His) Elastase-3A,ELA3A,Elastase IIIA,CELA3A,Chymotrypsin-Like Ela...	Human	HEK293 Cells
	Chymotrypsin-Like Elastase Family Member 3A (CELA3A) is an enzyme that contains one peptidase S1 domain. ELA3A belongs to the peptidase S1 family of the Elastase subfamily. ELA3A is secreted from the pancreas as a zymogen and, like other serine proteases such as trypsin, chymotrypsin and kallikrein, it has a digestive function in the intestine. ELA3A may also function in the intestinal transport and metabolism of cholesterol. ELA3A is efficient protease with alanine specificity but only little e...
TMPJ-01064	Serpin G1 Protein, Mouse, Recombinant (His) Serping1,Plasma protease C1 inhibitor,C1 Inh,C1 esterase inh...	Mouse	HEK293 Cells
	SERPIN G1 is a member of the serpin family, The C-terminal serpin domain is similar to other serpins, and this part of C1-INH provides the inhibitory activity. SERPIN G1 is involved in the inhibition of the complement system to prevent spontaneous activation. SERPIN G1 may play a potentially crucial role in regulating important physiological pathways including complement activation, blood coagulation, fibrinolysis and the generation of kinins. SERPIN G1 prevents the proteolytic cleavage of later...
TMPH-02832	Serpin A5 Protein, Mouse, Recombinant (His)	Mouse	Baculovirus Insect Cells
	Heparin-dependent serine protease inhibitor acting in body fluids and secretions. Inactivates serine proteases by binding irreversibly to their serine activation site. Involved in the regulation of intravascular and extravascular proteolytic activities. Plays hemostatic roles in the blood plasma. Acts as a procoagulant and proinflammatory factor by inhibiting the anticoagulant activated protein C factor as well as the generation of activated protein C factor by the thrombin/thrombomodulin comple...
TMPH-03106	Coagulation factor XII Protein, Pig, Recombinant (His) HAF,Hageman factor,F12,Coagulation factor XII	Sus scrofa (Pig)	E. coli
	Factor XII is a serum glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then trypsin cleaves it to beta-factor XIIa. Alpha-factor XIIa activates factor XI to factor XIa. Coagulation factor XII Protein, Pig, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predic...
TMPJ-00502	Serpin G1 Protein, Human, Recombinant (His) C1-Inhibiting Factor,Serpin G1,SERPING1,C1 Esterase Inhibito...	Human	HEK293 Cells
	As protease inhibitors, serpins have an array of functions including regulating blood clotting, the complement pathway, extracellular matrix remodeling, and cell motility. Serpin G1 is a serine protease inhibitor protein. It is the largest member among the serpin class of proteins. Remarkably, Serpin G1 has a 2-domain structure, unlike most family members. The C-terminal serpin domain is similar to other serpins, and this part of Serpin G1 provides the inhibitory activity. The N-terminal domain ...
TMPY-02242	Serpin B6 Protein, Human, Recombinant (His) DKFZp686I04222,PTI,SPI3,PI-6,RP1-90J20.6,serpin peptidase in...	Human	Baculovirus Insect Cells
	SerpinB6, also known as Cytoplasmic antiproteinase, Peptidase inhibitor 6, Placental thrombin inhibitor, SERPINB6 and PI-6, is a cytoplasm protein that belongs to the serpin family and Ov-serpin subfamily. SerpinB6 / PI-6 is an inhibitor of cathepsin G, kallikrein-8 and thrombin. It may play an important role in the inner ear in the protection against leakage of lysosomal content during stress and loss of this protection results in cell death and sensorineural hearing loss. SerpinB6 / PI-6 is ex...

重组蛋白

Kallikrein 5/KLK5 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01405

Species: Human

Expression System: HEK293 Cells

Kallikrein 3/KLK3 Protein, Human, Recombinant (His)

Cat.No: TMPY-02258

Species: Human

Expression System: HEK293 Cells

Kallikrein 2/KLK2 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00891

Species: Human

Expression System: HEK293 Cells

Kallikrein 15/KLK15 Protein, Human, Recombinant (His)

Cat.No: TMPY-05289

Species: Human

Expression System: HEK293 Cells

Kallikrein 1/KLK1 Protein, Human, Recombinant (His)

Cat.No: TMPY-00866

Species: Human

Expression System: HEK293 Cells

Kallikrein 1/KLK1 Protein, Human, Recombinant (aa 19-262, His)

Cat.No: TMPJ-00475

Species: Human

Expression System: HEK293 Cells

Kallikrein 1/KLK1 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-04032

Species: Mouse

Expression System: HEK293 Cells

Kallikrein 15/KLK15 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00491

Species: Human

Expression System: HEK293 Cells

Kallikrein 7/KLK7 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-03017

Species: Mouse

Expression System: HEK293 Cells

Kallikrein 4/KLK4 Protein, Human, Recombinant (His)

Cat.No: TMPY-01900

Species: Human

Expression System: HEK293 Cells

Kallikrein 15/KLK15 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-06608

Species: Mouse

Expression System: HEK293 Cells

KLKB1 Protein, Human, Recombinant (His)

Cat.No: TMPK-00766

Species: Human

Expression System: HEK293 Cells

Kallikrein 11/KLK11 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-02786

Species: Mouse

Expression System: HEK293 Cells

Kallikrein 5/KLK5 Protein, Mouse, Recombinant (His)

Cat.No: TMPK-01158

Species: Mouse

Expression System: HEK293 Cells

Kallikrein 7/KLK7 Protein, Human, Recombinant (His)

Cat.No: TMPY-01417

Species: Human

Expression System: HEK293 Cells

Kallikrein 13/KLK13 Protein, Human, Recombinant (His)

Cat.No: TMPY-00867

Species: Human

Expression System: HEK293 Cells

Kallikrein 11/KLK11 Protein, Human, Recombinant (His)

Cat.No: TMPY-01105

Species: Human

Expression System: HEK293 Cells

Kallikrein 6/KLK6 Protein, Human, Recombinant (His)

Cat.No: TMPY-02759

Species: Human

Expression System: HEK293 Cells

Kallikrein 8/KLK8 Protein, Human, Recombinant (His)

Cat.No: TMPY-01992

Species: Human

Expression System: HEK293 Cells

Kallikrein 7/KLK7 Protein, Human, Recombinant (aa 23-252, His)

Cat.No: TMPJ-00544

Species: Human

Expression System: HEK293 Cells

Kallikrein 8/KLK8 Protein, Human, Recombinant (aa 29-260, His)

Cat.No: TMPJ-00557

Species: Human

Expression System: HEK293 Cells

KLKB1 Protein, Mouse, Recombinant (His)

Cat.No: TMPK-00857

Species: Mouse

Expression System: HEK293 Cells

KLKB1 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-00525

Species: Cynomolgus

Expression System: HEK293 Cells

Serpin A4 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00931

Species: Human

Expression System: HEK293 Cells

Kallikrein-9 Protein, Human, Recombinant (hFc)

Cat.No: TMPH-01568

Species: Human

Expression System: HEK293 Cells

Kallikrein 8 Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02746

Species: Mouse

Expression System: P. pastoris (Yeast)

Kallikrein 14 Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02744

Species: Mouse

Expression System: E. coli

Kallikrein 15 Protein, S. cerevisiae, Recombinant (hFc)

Cat.No: TMPH-03465

Species: Saguinus oedipus

Expression System: HEK293 Cells

Kallikrein 8 Protein, Mouse, Recombinant (E. coli, His)

Cat.No: TMPH-02745

Species: Mouse

Expression System: E. coli

KLK10 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00468

Species: Human

Expression System: HEK293 Cells

Ecotin Protein, E. coli O127:H6, Recombinant (His & Myc)

Cat.No: TMPH-00661

Species: E. coli

Expression System: E. coli

Coagulation factor XI Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-01271

Species: Cynomolgus

Expression System: HEK293 Cells

CELA3A Protein, Human, Recombinant (His)

Cat.No: TMPJ-00481

Species: Human

Expression System: HEK293 Cells

Serpin G1 Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-01064

Species: Mouse

Expression System: HEK293 Cells

Serpin A5 Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02832

Species: Mouse

Expression System: Baculovirus Insect Cells

Coagulation factor XII Protein, Pig, Recombinant (His)

Cat.No: TMPH-03106

Species: Sus scrofa (Pig)

Expression System: E. coli

Serpin G1 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00502

Species: Human

Expression System: HEK293 Cells

Serpin B6 Protein, Human, Recombinant (His)

Cat.No: TMPY-02242

Species: Human

Expression System: Baculovirus Insect Cells

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