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132

抑制剂 & 化合物

10

天然产物

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Cat. No. Product Name Target Signaling Pathways
T22465 1,2-Distearoyl-sn-glycerol

Others Others
1,2-Distearoyl-sn-glycerol 是一种内标物,可用于分离和鉴定 1,2-diacyl-sn-glycerol (DAG) 的分子种类。
T6335 Tie2 kinase inhibitor 1

Tie2 kinase inhibitor

Tie-2 Tyrosine Kinase/Adaptors
Tie2 kinase inhibitor 1 (Tie2 kinase inhibitor) 是Tie2激酶选择性抑制剂9IC50:250 nM),具有抗癌作用。
T19658 Enflurane

NSC115944,Ethrane,NSC-115944,恩氟烷,Efrane,NSC 115944

Others Others
Enflurane (Efrane) 是一种挥发性麻醉剂,是 Chara australis 高电导 Ca2+ 激活的 K+ 通道的有效抑制剂。 安氟醚是通过顶空气相色谱-质谱法监测卤化挥发性麻醉剂的内标。 它可以快速调整麻醉深度,而脉搏或呼吸频率几乎没有变化。
T21230 Butyl decanoate

Butyl caprate,AI3-33573,Decanoic acid, butyl ester

Butyl decanoate could substitute hazardous compounds used in tissue processing and dewaxing, along with other compounds without impairing the diagnostic value of the tissue sections. It is also used as an internal standard to calculate the acid concentrat
T22214 1,5,5-Trimethylhydantoin

1,5,5-三甲基海因,TMH

Others Others
1,5,5-Trimethylhydantoin (TMH) 是非同位素内标化合物的一种。
T73712 Metformin-d6 hydrochloride

1,1-Dimethylbiguanide-d6 hydrochloride

AMPK; Autophagy Autophagy; Chromatin/Epigenetic; PI3K/Akt/mTOR signaling
Metformin-d6 hydrochloride (Metformin-d6 hydrochloride) 是 Metformin 的一种氘代化物,可用于研究 Metformin 在体内的代谢,常作为Metformin的内标。
T77493 Murlentamab

3C23K,GM102

Others Others
Murlentamab (GM102) 是一种人源化抗 AMHRII 抗体。Murlentama 具有潜在的抗肿瘤活性,可诱导巨噬细胞介导的抗体依赖的细胞介导的细胞毒性作用 (ADCC)。Murl可通过募,集、活化T细胞激发促炎和抗肿瘤内环境。Murlentama 通过促进幼稚的巨噬细胞定向,促进肿瘤相关巨噬细胞 (TAM) 重编程来发挥抗肿瘤活性。
T9428 HM43239

FLT Angiogenesis; Tyrosine Kinase/Adaptors
HM43239 是一种具有口服活性和选择性 FLT3抑制剂,IC50值为 1.1 nM (FLT3 野生型)、1.8 nM (FLT3 ITD 突变型) 和 1.0 nM (FLT3 D835Y 突变型)。HM43239 作为可逆的 I 型抑制剂直接抑制 FLT3 的激酶活性,并调节 p-STAT5, p-ERK SYK, JAK1/2 和 TAK1。HM43239 抑制白血病细胞的增殖并诱导其凋亡 (apoptosis)。
T34027 PhIP-D3

PhIP D3

PhIP-D3 is a deuterated internal standard for PhIP.
T68949 Chlorocitalopram hydrobromide

Chlorocitalopram hydrobromide is an internal standard of Citalopram -- an inhibitor of serotonin (5-HT) uptake.
T38182 C17 Sphingomyelin (d18:1/17:0)

C17 Sphingomyelin (d18:1/17:0)

C17 Sphingomyelin is a synthetic derivative of sphingomyelin that has been used as an internal standard for the quantification of sphingomyelin.
T37365 7-hydroxy Coumarin sulfate (potassium salt)

7-hydroxy Coumarin sulfate is a phase II metabolite of coumarin that can be used as an internal standard for the analysis of 7-hydroxy coumarin metabolism using GC- or LC-MS.
T19849 2-PADQZ

2PADQZ,2-PADQZ

DPQ is an antiviral compound. DPQ has also been shown to bind to a widened RNA major groove at the internal loop. DPQ acts against the H1N1 and H3N2 strains of influenza A as well as influenza B.
T15552 Iferanserin

S-MPEC

5-HT Receptor GPCR/G Protein; Neuroscience
Iferanserin (S-MPEC) is a selective antagonist of the 5-HT receptor (serotonin receptor) with an affinity for 5-HT2A receptors. Iferanserin has the potential for internal hemorrhoid disease treatment.
T12555 PROTAC FLT-3 degrader 1

Others Others
PROTAC FLT-3 degrader 1 is a PROTAC FLT-3 degrader of internal tandem duplication (ITD)(IC50 0.6 nM),with anti-proliferative activity.
T38185 C2 3'-sulfo Galactosylceramide (d18:1/2:0)

C2 3'-sulfo Galactosylceramide (d18:1/2:0)

C2 3'-sulfo Galactosylceramide is a member of the sulfatide class of glycolipids. It has been used as an internal standard in the quantification of lysosulfatides in mouse brain tissue and plasma.
T20616 Coumachlor

G-23133,Ratilan,G23133,Tomorin,G 23133

Coumachlor, a first-generation anticoagulant rodenticide, blocks the formation of prothrombin and inhibits blood coagulation causing internal haemorrhage.
T30935 ci-IP3/PM

CI-IP3 /PM is a cell-permeable caged inositol triphosphate that promotes the release of Ca2+ from internal storage under UV photolysis.
T38190 Tyr-α-CGRP (rat) (trifluoroacetate salt)

Tyr-α-CGRP (rat) is an N-terminally tyrosinated analog of the neuropeptide α-CGRP that induces a fall in resting tension of isolated opossum internal anal sphincter (IAS) with an EC50 value of 178 nM.
T19377 Ioxilan

Others Others
Ioxilan is a low-osmolar, nonionic, and tri-iodinated diagnostic contrast agent used for excretory urography and contrast-enhanced computed tomographic (CECT) imaging of the head and body. Intravascularly injected causes opacification of vessels, allowing for radiographic visualization of internal structures until significant hemodilution occurs.
T72001 CB096

CB096 is a novel inhibitor of RAN translation. specifically binds to a repeating 1 × 1 GG internal loop structure, 5'CGG/3'GGC, that is formed when r(G4C2)exp folds, also acting as a potent vasorelaxant agent, showing antihypertensive effect.
T37327 Prostaglandin F2α 1,15-lactone

Prostaglandin F2α 1,15-lactone

PGF2α 1,15-lactone is a lipid-soluble internal ester of PGF2α. Hydrolysis of the lactone readily produces free PGF2α in plasma. In rhesus monkeys, a total dose of 15 mg of PGF2α 1,15-lactone terminates early pregnancy, whereas PGF2α is ineffective.
T70350 Caspofungin

Caspofungin is a cyclic lipopeptide echinocandin and beta-(1,3)-D-glucan synthase inhibitor that is used to treat internal or systemic mycoses.
T39818 Desmorpholinyl Quizartinib-PEG2-COOH

Desmorpholinyl Quizartinib-PEG2-COOH

Desmorpholinyl Quizartinib-PEG2-COOH is a compound featuring an FLT-3 ligand and a PEG-based PROTAC linker. It is employed in the synthesis of PROTAC FLT-3 degrader 1, which serves as a degrader for the FLT-3 internal tandem duplication (ITD) through PROTAC technology. The degrader exhibits an IC50 of 0.6 nM.
T61415 FLT3/ITD-IN-1

FLT3/ITD-IN-1 (Compound 1) is a highly potent inhibitor of FLT3 internal tandem duplications (FLT3-ITD). It exhibits remarkable inhibitory effects against FLT3 and FLT3-ITD, with impressive IC50 values of 38.2 nM and 144.1 nM, respectively. Moreover, FLT3/ITD-IN-1 shows exceptional antiproliferative activities against several acute myeloid leukemia cell lines [1].
T38037 Caffeic Acid-13C3

Caffeic Acid-13C3

Caffeic acid-13C3 is an isotopically enriched form of caffeic acid that is intended for use as an internal standard for the quantification of caffeic acid by GC- or LC-MS. Caffeic acid is an inhibitor of 5-LO , with IC50 values of 3.7-72 μM, and 12-LO, with IC50 values of 5.1-30 μM.
T36437 Sphinganine (d17:0)

Sphinganine (d17:0)

Sphinganine is a synthetic bioactive sphingolipid that inhibits the growth of C. glabrata and C. albicans with a minimum fungicidal concentration (MFC) value of 0.5 μg/ml for both. More commonly, sphinganine is used as an internal standard in the analysis of sphingoid compounds by chromatographic or spectrometric methods.
T36217 19-hydroxy Cholesterol

19-hydroxy Cholesterol is formed during metabolic oxidation of cholesterol. It has been used as an internal standard for the quantitative determination of sterols by mass spectroscopic analysis.[1]
T37438 C17 Globotriaosylceramide (d18:1/17:0)

C17 Globotriaosylceramide (d18:1/17:0)

C17 Globotriaosylceramide is a sphingolipid that has been used as an internal standard for the quantification of globotriaosylceramides in plasma and urine from patients with Fabry disease by GC-MS.
T38056 Cholesteryl Arachidate

Cholesterol Arachidate

Cholesteryl arachidate is a cholesterol ester that has been found in human meibum.[1][2] It has been used as an internal standard for the quantification of fatty acids in B. napus.[3]
T40419 IRES-C11

IRES-C11

c-Myc Cell Cycle/Checkpoint
IRES-C11 is a specific inhibitor of translation that targets the internal ribosome entry site (IRES) of the c-MYC gene. It functions by blocking the interaction between heterogeneous nuclear ribonucleoprotein A1, a trans-acting factor required for c-MYC IRES activity, and its corresponding IRES. Notably, IRES-C11 does not inhibit the IRES activity of BAG-1, XIAP, and p53.
T37147 5'-O-DMT-N4-Ac-dC

5'-O-DMT-N4-Ac-dC

5'-O-DMT-N4-Ac-dC (N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine, compound 7) is a deoxynucleoside utilized in the synthesis of dodecyl phosphoramidite. Dodecyl phosphoramidite serves as a crucial precursor for dod-DNA production, which is amphiphilic DNA comprising dodecyl phosphotriester linkages and featuring an internal hydrophobic region[1][2].
T36383 L-Thyroxine-13C9,15N

L-Thyroxine-13C9,15N

L-Thyroxine-13C9,15N is intended for use as an internal standard for the quantification of L-thyroxine by GC- or LC-MS. L-Thyroxine is a synthetic form of the thyroid hormone thyroxine. In vivo, L-thyroxine (0.9 and 2.7 μg) inhibits synthesis and release of thyrotropin induced by thyrotropin-releasing hormone from the anterior pituitary in mice. It also reverses decreases in levels of circulating thymic serum factor (FTS) and the number of T rosette-forming cells in an old age-induced mouse mode...
T76161 Bacterial α-Amylase

Bacterialα-Amylase 通过催化淀粉的α-1,4-糖苷键的水解反应,生成低分子量产物,例如葡萄糖和麦芽糖,广泛应用于生化研究中。
T35521 Aflatoxin G2-13C17

Aflatoxin G2-13C17

Aflatoxin G2-13C17is intended for use as an internal standard for the quantification of aflatoxin G2by GC- or LC-MS. Aflatoxin G2is a mycotoxin that has been found inAspergillus.1It is lethal to ducklings (LD50= 2.83 mg/kg) but is non-toxic to rats when administered at a dose of 200 mg/kg.2 1.Bennett, J.W., and Klich, M.MycotoxinsClin. Microbiol. Rev.16(3)497-516(2003) 2.Wogan, G.N., Edwards, G.S., and Newberne, P.M.Structure-activity relationships in toxicity and carcinogenicity of aflatoxins a...
T37344 5,6-dimethyl-2-Thiouracil

5,6-dimethyl-2-Thiouracil is a heterocyclic building block that has been used in the synthesis of anti-HIV-1 pyrimidinones.1 It has also been used as an internal standard for the quantification of thyreostats, including 2-thiouracil, in bovine plasma.2 |1. Navrotskii, M.B. Synthesis and anti-HIV-1 activity of new 2-[(2-phthalimidoethyl)thio]-4(3H)-pyrimidinone derivatives. Pharm. Chem. J. 39(9), 466-467 (2005).|2. Schmidt, K.S. In-house validation and factorial effect analysis of a liquid chroma...
T35515 3-Acetyldeoxy Nivalenol-13C17

3-Acetyldeoxy Nivalenol-13C17

3-Acetyldeoxy nivalenol-13C17is intended for use as an internal standard for the quantification of 3-acetyldeoxy nivalenol by GC- or LC-MS. 3-Acetyldeoxy nivalenol is a mycotoxin that has been found inF. graminearum.1In vivo, 3-acetyldeoxy nivalenol (40 mg/kg) induces duodenal and splenic cell necrosis, as well as lethality (LD50= 70 mg/kg) in mice.2 1.Jiao, F., Kawakami, A., and Nakajima, T.Effects of different carbon sources on trichothecene production and Tri gene expression by Fusarium grami...
T76385 [Tyr8] Bradykinin

[Tyr8] Bradykinin 是B2激肽受体 (B2kinin receptor) 的激动剂,能刺激ERK1/2磷酸化,并可作为内标。
T36895 5-Fluorouracil-13C,15N2

5-Fluorouracil-13C,15N2

5-Fluorouracil-13C,15N2 is intended for use as an internal standard for the quantification of 5-flurouracil by GC- or LC-MS. 5-Fluorouracil is a pyrimidine analog that irreversibly inhibits thymidylate synthase, blocking the synthesis of thymidine which is required for DNA synthesis. Intracellular metabolites of 5-fluorouracil exert cytotoxic effects by either inhibiting thymidylate synthetase, or through incorporation into RNA and DNA, ultimately initiating apoptosis.
T37058 D-myo-Inositol-1,3,4,5-tetraphosphate (sodium salt)

D-myo-Inositol-1,3,4,5-tetraphosphate (Ins(1,3,4,5)-P4) is formed by the phosphorylation of Ins(1,4,5)P3 by inositol 1,4,5-triphosphate 3-kinase. Ins(1,3,4,5)-P4 increases intracellular calcium levels by two distinct mechanisms: opening calcium channels on both the endoplasmic reticulum to release calcium from internal stores and on the plasma membrane to allow the influx of calcium from outside the cell.
T36537 Nitrofurantoin-13C3

Nitrofurantoin-13C3

Nitrofurantoin-13C3is intended for use as an internal standard for the quantification of nitrofurantoin by GC- or LC-MS. Nitrofurantoin is a nitrofuran antibiotic.1In vivo, nitrofurantoin (25-100 mg/kg) reducesE. colireplication and abscess formation in the renal medulla of infected rats in a dose-dependent manner. It prevents kidney and bladder infection in rats following bladder inoculation with clinical isolates ofP. mirabilis. Nitrofurantoin also prevents alkalization of urine, as well as ca...
T71326 1,3,7-Trimethyluric Acid-d9

1,3,7-Trimethyluric acid-d9 is intended for use as an internal standard for the quantification of 1,3,7-trimethyluric acid by GC- or LC-MS. 1,3,7-Trimethyluric acid is a derivative of uric acid and a metabolite of caffeine. It is formed from caffeine by the cytochrome P450 isoform CYP3A4. 1,3,7-Trimethyluric acid scavenges hydroxyl radicals in a cell-free assay and inhibits t-butyl hydroperoxide-induced lipid peroxidation by 56.5% in isolated human erythrocyte membranes.
T37682 3-hydroxy Tridecanoic Acid

3-hydroxy Tridecanoic acid is a 13-carbon saturated fatty acid found in bacterial lipopolysaccharides (LPS). It can be used as an internal standard to detect markers of microorganisms in complex samples, including 3-hydroxy fatty acids found in LPS-containing bacteria and muramic acid found in bacterial cell wall peptidoglycan.
T37250 Cefazolin-13C2,15N

Cefazolin-13C2,15N

Cefazolin-13C2,15N is intended for use as an internal standard for the quantification of cefazolin by GC- or LC-MS. Cefazolin is a broad-spectrum cephalosporin antibiotic that is active in vitro against various Gram-positive and Gram-negative bacteria (MICs = 0.2-12.5 μg/ml). It also inhibits the growth of clinical isolates of S. aureus, E. coli, P. mirabilis, and K. pneumoniae (MICs = 0.1-25 μg/ml). In vivo, cefazolin protects against S. aureus, E. coli, and P. mirabilis infection in mice (ED50...
T37178 Norhyodeoxycholic Acid

Norhyodeoxycholic acid (NHDCA) is a synthetic bile acid and a derivative of hyodeoxycholic acid .1,2 NHDCA is an intermediate in the synthesis of 3β-sulfooxy-7β-hydroxy-24-nor-5-cholen-23-oic acid, which has been used as an internal standard for the quantification of δ5-bile acid conjugates that have been identified in patients with Niemann-Pick disease type C1.3 |1. Schteingart, C.D., and Hofmann, A.F. Synthesis of 24-nor-5β-cholan-23-oic acid derivatives: A convenient and efficient one-carbon ...
T78353 alpha-2,6-Sialyltransferase (Pd26ST)

alpha-2,6-Sialyltransferase (Pd26ST) 能够催化末端和内部半乳糖及N-乙酰半乳糖胺的唾液酸化,形成末端α2,6-唾液酸苷。
T76153 PNGase F

PNGase F 是一种糖苷酶,可催化寡糖中内部糖苷键的裂解。PNGase F 可从糖蛋白中去除几乎所有的 N-连接寡糖。
T35697 Lauric Acid-13C

Lauric acid-13C is intended for use as an internal standard for the quantification of lauric acid by GC- or LC-MS. Lauric acid is a medium-chain saturated fatty acid. It has been found at high levels in coconut oil.1Lauric acid induces the activation of NF-κB and the expression of COX-2, inducible nitric oxide synthase (iNOS), and IL-1α in RAW 264.7 cells when used at a concentration of 25 μM.2
T71329 Theophylline-d6

Theophylline-d6 is intended for use as an internal standard for the quantification of theophylline by GC- or LC-MS. Theophylline is an inhibitor of phosphodiesterase. It is also an adenosine A1 and A2 receptor antagonist. Theophylline induces relaxation of isolated cat bronchial smooth muscle segments precontracted with acetylcholine. It inhibits ovalbumin-induced increases in bronchoalveolar lavage fluid (BALF) eosinophil infiltration in an ovalbumin-sensitized mouse model of allergic asthma. F...
T71065 Quinapril-d5

Quinapril-d5 is intended for use as an internal standard for the quantification of quinapril by GC- or LC-MS. Quinapril is a prodrug form of the angiotensin converting enzyme (ACE) inhibitor quinaprilat. In vivo, quinapril reduces mean arterial pressure in renal hypertensive and spontaneously hypertensive rats. It inhibits angiotensin I-induced pressor responses in normotensive rats and dogs. Quinapril prevents left ventricular heart failure in CHF 14.6 cardiomyopathic hamsters. Formulations con...

化合物

1,2-Distearoyl-sn-glycerol
Cat.No: T22465
Synonym:
Target: Others
Tie2 kinase inhibitor 1
Cat.No: T6335
Synonym: Tie2 kinase inhibitor
Target: Tie-2
Enflurane
Cat.No: T19658
Synonym: NSC115944,Ethrane,NSC-115944,恩氟烷,Efrane,NSC 115944
Target: Others
Butyl decanoate
Cat.No: T21230
Synonym: Butyl caprate,AI3-33573,Decanoic acid, butyl ester
Target:
1,5,5-Trimethylhydantoin
Cat.No: T22214
Synonym: 1,5,5-三甲基海因,TMH
Target: Others
Metformin-d6 hydrochloride
Cat.No: T73712
Synonym: 1,1-Dimethylbiguanide-d6 hydrochloride
Target: AMPK, Autophagy
Murlentamab
Cat.No: T77493
Synonym: 3C23K,GM102
Target: Others
HM43239
Cat.No: T9428
Synonym:
Target: FLT
PhIP-D3
Cat.No: T34027
Synonym: PhIP D3
Target:
Chlorocitalopram hydrobromide
Cat.No: T68949
Synonym:
Target:
C17 Sphingomyelin (d18:1/17:0)
Cat.No: T38182
Synonym: C17 Sphingomyelin (d18:1/17:0)
Target:
7-hydroxy Coumarin sulfate (potassium salt)
Cat.No: T37365
Synonym:
Target:
2-PADQZ
Cat.No: T19849
Synonym: 2PADQZ,2-PADQZ
Target:
Iferanserin
Cat.No: T15552
Synonym: S-MPEC
Target: 5-HT Receptor
PROTAC FLT-3 degrader 1
Cat.No: T12555
Synonym:
Target: Others
C2 3'-sulfo Galactosylceramide (d18:1/2:0)
Cat.No: T38185
Synonym: C2 3'-sulfo Galactosylceramide (d18:1/2:0)
Target:
Coumachlor
Cat.No: T20616
Synonym: G-23133,Ratilan,G23133,Tomorin,G 23133
Target:
ci-IP3/PM
Cat.No: T30935
Synonym:
Target:
Tyr-α-CGRP (rat) (trifluoroacetate salt)
Cat.No: T38190
Synonym:
Target:
Ioxilan
Cat.No: T19377
Synonym:
Target: Others
CB096
Cat.No: T72001
Synonym:
Target:
Prostaglandin F2α 1,15-lactone
Cat.No: T37327
Synonym: Prostaglandin F2α 1,15-lactone
Target:
Caspofungin
Cat.No: T70350
Synonym:
Target:
Desmorpholinyl Quizartinib-PEG2-COOH
Cat.No: T39818
Synonym: Desmorpholinyl Quizartinib-PEG2-COOH
Target:
FLT3/ITD-IN-1
Cat.No: T61415
Synonym:
Target:
Caffeic Acid-13C3
Cat.No: T38037
Synonym: Caffeic Acid-13C3
Target:
Sphinganine (d17:0)
Cat.No: T36437
Synonym: Sphinganine (d17:0)
Target:
19-hydroxy Cholesterol
Cat.No: T36217
Synonym:
Target:
C17 Globotriaosylceramide (d18:1/17:0)
Cat.No: T37438
Synonym: C17 Globotriaosylceramide (d18:1/17:0)
Target:
Cholesteryl Arachidate
Cat.No: T38056
Synonym: Cholesterol Arachidate
Target:
IRES-C11
Cat.No: T40419
Synonym: IRES-C11
Target: c-Myc
5'-O-DMT-N4-Ac-dC
Cat.No: T37147
Synonym: 5'-O-DMT-N4-Ac-dC
Target:
L-Thyroxine-13C9,15N
Cat.No: T36383
Synonym: L-Thyroxine-13C9,15N
Target:
Bacterial α-Amylase
Cat.No: T76161
Synonym:
Target:
Aflatoxin G2-13C17
Cat.No: T35521
Synonym: Aflatoxin G2-13C17
Target:
5,6-dimethyl-2-Thiouracil
Cat.No: T37344
Synonym:
Target:
3-Acetyldeoxy Nivalenol-13C17
Cat.No: T35515
Synonym: 3-Acetyldeoxy Nivalenol-13C17
Target:
[Tyr8] Bradykinin
Cat.No: T76385
Synonym:
Target:
5-Fluorouracil-13C,15N2
Cat.No: T36895
Synonym: 5-Fluorouracil-13C,15N2
Target:
D-myo-Inositol-1,3,4,5-tetraphosphate (sodium salt)
Cat.No: T37058
Synonym:
Target:
Nitrofurantoin-13C3
Cat.No: T36537
Synonym: Nitrofurantoin-13C3
Target:
1,3,7-Trimethyluric Acid-d9
Cat.No: T71326
Synonym:
Target:
3-hydroxy Tridecanoic Acid
Cat.No: T37682
Synonym:
Target:
Cefazolin-13C2,15N
Cat.No: T37250
Synonym: Cefazolin-13C2,15N
Target:
Norhyodeoxycholic Acid
Cat.No: T37178
Synonym:
Target:
alpha-2,6-Sialyltransferase (Pd26ST)
Cat.No: T78353
Synonym:
Target:
PNGase F
Cat.No: T76153
Synonym:
Target:
Lauric Acid-13C
Cat.No: T35697
Synonym:
Target:
Theophylline-d6
Cat.No: T71329
Synonym:
Target:
Quinapril-d5
Cat.No: T71065
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T8067 Methyl Nonadecanoate

Nonadecanoic Acid methyl ester,正十九酸甲酯

Others Others
Methyl Nonadecanoate (Nonadecanoic Acid methyl ester)是一种内标物,能够用于生物柴油中脂肪酸甲酯含量的测定。
T8027 2-Ethylbutyric Acid

Others Others
2-Ethylbutyric acid 是一种内标物,可用于粪便的 VFA 分析标准的校准方法。
T19615 α-Amylase

Amylase Metabolism
α-Amylase 是一种能够催化淀粉中 α-1,4-糖苷键水解的水解酶,使淀粉产生葡萄糖、麦芽糖等产物。
TN1136 Procyanidin A1

原花青素 A1,Proanthocyanidin A1,原花色素A1

LDL; Calcium Channel; PKC Chromatin/Epigenetic; Cytoskeletal Signaling; Membrane transporter/Ion channel; Metabolism
Procyanidin A1 (Proanthocyanidin A1) 是一种原花青素二聚体,具有抗过敏作用,可抑制蛋白激酶 C 激活下游脱粒或 RBL-213 细胞内部储存的 Ca2+流入。
T35618 D-Fructose-13C6

D-果糖 13C6

Others Others
D-Fructose-13C6 可用作通过 GC-或 LC-MS 定量 D-果糖的内标。
T5917 2-Hydroxy-6-methoxybenzoic acid

6-甲氧基水杨酸,2-羟基-6-甲氧基苯甲酸,6-Methoxysalicylic acid

Others Others
2-Hydroxy-6-methoxybenzoic acid (6-Methoxysalicylic acid) 可用于动物血浆中乙酸水杨酸及其主要代谢物水杨酸含量的测定,表现出较好的抗缓解疼痛活性。
T1353 DL-Mevalonolactone

甲瓦龙酸内酯,Mevalonolactone

Others; Endogenous Metabolite Metabolism; Others
DL-Mevalonolactone (Mevalonolactone),一种人内源性代谢物,是甲羟戊酸的 δ-lactone 形式,甲羟戊酸途径的一个前体。它能够降低大脑中线粒体膜电位(∆Ψm),Ca2+的保留能力和 NAD (P) H 的含量 , 而且还诱导线粒体肿胀。
T78473 Sphingosine (d17:1)

C17 Sphingosine

Sphingosine (d17:1) (C17 Sphingosine)是一种存在于人类皮肤中的17碳鞘脂,可被鞘氨醇激酶的磷酸化。Sphingosine C-17作为内标可用于进行鞘脂类化合物的光谱分析。
T5S0106 Peimisine

贝母辛,Ebeiensine

RAAS; AChR Endocrinology/Hormones; Neuroscience
Peimisine (Ebeiensine) 非竞争性拮抗气管平滑肌 M 受体,抑制 Ach 引起的平滑肌收缩。它兴奋 β 受体和拮抗内钙释放,促进一氧化氮释放,可舒张气管平滑肌,有平喘作用。
T38179 C16 3'-sulfo Galactosylceramide (d18:1/16:0)

C16 3'-sulfo Galactosylceramide (d18:1/16:0)

Others Others
C16 3'-sulfo Galactosylceramide (d18:1/16:0)是硫酸盐类糖脂的一种。C16 3'-sulfo Galactosylceramide (d18:1/16:0)是在猪脑和血浆中发现的一种比较丰富的硫化物,在小鼠的整个发育过程中会有所减少。C16 3'-sulfo Galactosylceramide (d18:1/16:0)在体外可抑制视网膜神经节细胞生长。C16 3'-sulfo Galactosylceramide (d18:1/16:0)已被用作量化大鼠小脑和多发性硬化症患者分离的白质中的硫化物的参照物。

天然产物

Methyl Nonadecanoate
Cat.No: T8067
Synonym: Nonadecanoic Acid methyl ester,正十九酸甲酯
Target: Others
2-Ethylbutyric Acid
Cat.No: T8027
Synonym:
Target: Others
α-Amylase
Cat.No: T19615
Synonym:
Target: Amylase
Procyanidin A1
Cat.No: TN1136
Synonym: 原花青素 A1,Proanthocyanidin A1,原花色素A1
Target: LDL, Calcium Channel, PKC
D-Fructose-13C6
Cat.No: T35618
Synonym: D-果糖 13C6
Target: Others
2-Hydroxy-6-methoxybenzoic acid
Cat.No: T5917
Synonym: 6-甲氧基水杨酸,2-羟基-6-甲氧基苯甲酸,6-Methoxysalicylic acid
Target: Others
DL-Mevalonolactone
Cat.No: T1353
Synonym: 甲瓦龙酸内酯,Mevalonolactone
Target: Others, Endogenous Metabolite
Sphingosine (d17:1)
Cat.No: T78473
Synonym: C17 Sphingosine
Target:
Peimisine
Cat.No: T5S0106
Synonym: 贝母辛,Ebeiensine
Target: RAAS, AChR
C16 3'-sulfo Galactosylceramide (d18:1/16:0)
Cat.No: T38179
Synonym: C16 3'-sulfo Galactosylceramide (d18:1/16:0)
Target: Others
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