ctp

CTP为一种具心脏靶向性的肽。它在体外能够转导心肌细胞，并能有效特异性地转导小鼠心脏组织。CTP可专门用于将治疗性肽、蛋白质及核酸传递至心脏。

CTP-NBD (CTP-NBD) 是一种具有细胞渗透性的特异性 NFκB (NFκB) 抑制剂，常用于结肠炎研究。

HYNIC-CTP 是 HYNIC 与 CTP (心脏靶向肽) 的结合物。它通过 HYNIC 作为螯合剂与放射性同位素 99mTc 结合，形成 99mTc-HYNIC-CTP。该化合物可被心脏特异性吸收，可用于心脏成像以及心脏疾病的研究。

β-Endorphin (β-EP) is an endogenous opioid neuropeptide with diverse biological activities. It is produced via piomelanocortin cleavage in the pituitary gland, hypothalamus, and in lymphocytes, then migrates to its sites of action which include plasma, gut, skin, placenta, cerebrospinal fluid, and cardiac tissues. β-EP induces concentration-dependent decreases in electrically stimulated contraction of the mouse vas deferens that can be reversed by the μ-opioid antagonist CTP and δ-opioid antagonist ICI 174,864. In vivo, β-EP (5 μg, i.c.v.) slows gastrointestinal transit in mice. β-EP (0.5 or 5 μg, i.c.v.) stimulates food intake in rats for 4 to 6 hours, however, this effect is not prolonged with continuous infusion. It antagonizes the appetite-suppressive effects of α-melanocyte-stimulating hormone (α-MSH) for the first three days post administration. β-EP also reduces paralytic demyelination induced by the murine coronavirus MHV-JHM in immunocompetent, but not irradiated or immune-incompetent, mice and rats.