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    TargetMol | Inhibitors_Agonists
  • PDE2A-IN-1
    PDE2A-IN-1
    T402782648290-28-0
    PDE2A-IN-1 is a phosphodiesterase 2A (PDE2A) inhibitor with an IC 50 value of 1.3 nM.
    • ¥ 10600
    6-8周
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  • CP 461
    OSI 461, UNII-68OJX9I7DT, CP-461, CP461
    T31020227619-96-7In house
    CP 461 (UNII-68OJX9I7DT) 是一种特异性 PDE2A 抑制剂,是一种新型促凋亡化合物,能抑制环 GMP 磷酸二酯酶,但不能抑制环氧化酶-1 或-2。CP 461 在体外可抑制多种人类肿瘤细胞系的生长,并选择性地诱导癌细胞系而不是正常细胞凋亡。
    • ¥ 780
    In stock
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    TargetMol | Inhibitor Sale
  • Hcyb1
    T61617
    Hcyb1 is a potent and specific inhibitor of phosphodiesterase 2 (PDE2). It exhibits a high degree of selectivity for inhibiting PDE2A with an IC50 value of 0.57 μM. In addition, Hcyb1 displays over 250-fold selectivity against other recombinant members of the PDE family. Moreover, its pharmacological actions include neuroprotective and antidepressant-like effects, which are believed to be mediated through the cAMP cGMP-CREB-BDNF signaling pathway [1].
    • ¥ 9160
    10-14周
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    数量