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Search Results for " parc "

Targets Recommended: Others

7

抑制剂 & 化合物

7

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T68002L	(R)-Naroparcil 4-[4-[(5-Thio-α-D-xylopyranosyl)thio]benzoyl]benzonitrile(Isomer-120819-70-7)	Others	Others
	(R)-Naroparcil 是 Naroparcil 的异构体。 Naroparcil 是一种4-甲基伞形酮基 β-D-木糖苷类似物，与血管平滑肌细胞增殖有关，在 Wessler 淤滞模型中抑制血栓的形成。
T68002	Naroparcil	Thrombin	Proteases/Proteasome
	Naroparcil 是一种可口服的硫代苷类化合物，是一种 4-甲基伞形 β-D-木糖苷类似物，在静脉血栓形成（颈静脉）的Wessler淤滞模型中显示出抗血栓形成作用。Naroparcil 增强了凝血酶/肝素辅因子II复合物的形成，诱导了处理兔血浆中硫酸皮肤素样物质的出现，但减少了与（125I）-人α-凝血酶孵育的血浆中的凝血酶/抗凝血酶III复合物的形成。
T12361	Parcetasal MR-897	Others	Others
	Parcetasal (MR-897) 是一种非甾类体抗炎剂，在缓解疼痛方面具有研究价值。
T67991	Iliparcil	Others	Others
	Iliparcil 是一种具有口服活性的抗血栓化合物。
T16377	Odiparcil SB-424323	Thrombin	Proteases/Proteasome
	Odiparcil is an orally active beta-d-thioxyloside analog. Odiparcil is an indirect thrombin inhibitor that exerts its anticoagulant effect through activation of antithrombin II (heparin cofactor II). It also has an antithrombotic activity associated with a reduced risk of adverse bleeding events.
T68998	Parconazole Free Base
	Parconazole Free Base is used in veterinary as an oral fungicide with a broad-spectrum activity against dermatophytes, yeasts, and others fungi. This compound does not have any antibacterial effect. The mechanism of action involves inhibition of the fungal cytochrome P450 dependent 14alpha-dimethylation of lanosterol to ergosterol.
T1283	Clinafloxacin 克林沙星,PD 127391,CI-960,AM-1091	Antibacterial; Antibiotic	Microbiology/Virology
	Clinafloxacin (CI-960) 是一种高效广谱氟喹诺酮类抗生素，抑制革兰氏阳性、革兰氏阴性和厌氧病原体。它对金黄色葡萄球菌的 DNA 促旋酶和拓扑异构酶 IV 有抑制作用，IC50值分别为 0.92 µg/ml 和 1.62 µg/ml。

化合物

Cat.No: T68002L

Synonym: 4-[4-[(5-Thio-α-D-xylopyranosyl)thio]benzoyl]benzonitrile(Isomer-120819-70-7)

Target: Others

Cat.No: T68002

Target: Thrombin

Cat.No: T12361

Synonym: MR-897

Target: Others

Cat.No: T67991

Target: Others

Cat.No: T16377

Synonym: SB-424323

Target: Thrombin

Parconazole Free Base

Cat.No: T68998

Cat.No: T1283

Synonym: 克林沙星,PD 127391,CI-960,AM-1091

Target: Antibacterial, Antibiotic

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-00566	CCL18 Protein, Human, Recombinant (His) PARC,CCL18,CKb7,DC-CK1,chemokine (C-C motif) ligand...	Human	P. pastoris (Yeast)
	CCL18 is a chemotactic cytokine involved in the pathogenesis and progression of various disorders, including cancer. Proof showed high levels of CCL18 in the serum of epithelial ovarian carcinoma patients suggesting its potential as a circulating biomarker. CCL18 chemokine has an important role in chemokine-mediated tumor metastasis, and may serve as a potential predictor for poor survival outcomes for ovarian cancer. (CCL18) is predominantly secreted by M2-tumor associated macrophages (TAMs) a...
TMPK-00657	SPARC Protein, Cynomolgus, Recombinant (His) BM-40,EGM_15571,SPARC,ON	Cynomolgus	HEK293 Cells
	Secreted protein acidic and rich in cysteine (SPARC/osteonectin/BM40) is one of the most abundant non-collagenous protein expressed in mineralized tissues.The capacity of SPARC to influence pathways involved in extracellular matrix assembly such as procollagen processing and collagen fibril formation as well as the capacity to influence osteoblast differentiation and osteoclast activity will be addressed.
TMPY-00090	SPARCL1 Protein, Mouse, Recombinant (His) Sc1,SPARC like 1,mast9,hevin,Ecm2	Mouse	HEK293 Cells
	SPARC-like protein 1 (SPARCL1; also known as SC1, high endothelial venule protein, or hevin) is an extracellular matrix-associated, secreted glycoprotein belonging to the secreted protein acidic and rich in cysteine (SPARC) family of matricellular proteins. It contains three conserved structural domains that are implicated in the regulation of cell adhesion, migration, and proliferation. SPARCL1 is expressed during embryogenesis and tissue remodeling and is especially prominent in brain and vasc...
TMPY-04814	SPARC Protein, Rat, Recombinant (His) SPARC,secreted protein, acidic, cysteine-rich (oste...	Rat	HEK293 Cells
	SPARC Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 33.8 kDa.
TMPY-01182	SPARC Protein, Human, Recombinant (His) BM-40,ON,SPARC,secreted protein, acidic, cysteine-r...	Human	HEK293 Cells
	SPARC Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 34 kDa and the accession number is P09486.
TMPY-01796	SPARC Protein, Mouse, Recombinant (His) AA517111,secreted protein, acidic, cysteine-rich (osteonecti...	Mouse	HEK293 Cells
	SPARC Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 34 kDa and the accession number is P07214.
TMPH-00610	gyrA Protein, E. coli, Recombinant (His)	E. coli	E. coli
	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to maintain chromosomes in an underwound state. This makes better substrates for topoisomerase IV (ParC and ParE) which is the main enzyme that unlinks newly replicated chromosomes in E.coli. Gyrase catalyzes the interconversion of other topological isomers of dsDNA rings, including catenanes. Relaxes negatively supercoiled DNA in an ATP-independent manner. E.coli gyrase has hig...

重组蛋白

CCL18 Protein, Human, Recombinant (His)

Cat.No: TMPY-00566

Species: Human

Expression System: P. pastoris (Yeast)

SPARC Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-00657

Species: Cynomolgus

Expression System: HEK293 Cells

SPARCL1 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-00090

Species: Mouse

Expression System: HEK293 Cells

SPARC Protein, Rat, Recombinant (His)

Cat.No: TMPY-04814

Species: Rat

Expression System: HEK293 Cells

SPARC Protein, Human, Recombinant (His)

Cat.No: TMPY-01182

Species: Human

Expression System: HEK293 Cells

SPARC Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01796

Species: Mouse

Expression System: HEK293 Cells

gyrA Protein, E. coli, Recombinant (His)

Cat.No: TMPH-00610

Species: E. coli

Expression System: E. coli

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