Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T39899 | Hu7691 | Akt | Cytoskeletal Signaling; PI3K/Akt/mTOR signaling |
Hu7691 是一种具有口服活性、选择性和高效性的 Akt 抑制剂,抑制 Akt1、Akt2 和 Akt3,抑制神经母细胞瘤细胞增殖,诱导神经母细胞瘤细胞的分化。 | |||
T39733 | Hu7691 free base | ||
Hu7691 free base is an orally active, selective Akt inhibitor. It exhibits IC50 values of 4.0 nM, 97.5 nM, and 28 nM for Akt1, Akt2, and Akt3, respectively. Furthermore, it effectively inhibits tumor growth and facilitates a reduction in cutaneous toxicity in mice. |