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Anti-UBE3A Antibody (4P437) 是一种 Rabbit 抗体,靶向 UBE3A。Anti-UBE3A Antibody (4P437) 可用于 WB。
Anti-UBE3A Antibody (4P437) 是一种 Rabbit 抗体,靶向 UBE3A。Anti-UBE3A Antibody (4P437) 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 μL | ¥ 785 | 5日内发货 | |
| 50 μL | ¥ 1,390 | 5日内发货 | |
| 100 μL | ¥ 2,480 | 5日内发货 |
| 产品描述 | Anti-UBE3A Antibody (4P437) is a Rabbit antibody targeting UBE3A. Anti-UBE3A Antibody (4P437) can be used in WB. |
| Ig Type | IgG |
| 克隆号 | 4P437 |
| 反应种属 | Human,Mouse,Rat |
| 应用 | WB |
| 推荐剂量 | WB: 1:1000-2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Nucleus. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| 研究背景 | E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. Several substrates have been identified including the RAD23A and RAD23B, MCM7 (which is involved in DNA replication), annexin A1, the PML tumor suppressor, and the cell cycle regulator CDKN1B. |
| 免疫原 | A synthesized peptide: human UBE3A |
| 抗原种属 | Human |
| 基因名称 | UBE3A |
| 基因ID | |
| 蛋白名称 | Ubiquitin-protein ligase E3A |
| Uniprot ID | |
| 功能 | E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. Several substrates have been identified including the RAD23A and RAD23B, MCM7 (which is involved in DNA replication), annexin A1, the PML tumor suppressor, and the cell cycle regulator CDKN1B. Additionally, may function as a cellular quality control ubiquitin ligase by helping the degradation of the cytoplasmic misfolded proteins. Finally, UBE3A also promotes its own degradation in vivo. |
| 分子量 | Theoretical: 101 kDa. Actual: 100 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |