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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Hepcidin-25 Antibody (7S819)

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货号 TMAB-06979

Anti-Hepcidin-25 Antibody (7S819) 是一种 Rabbit 抗体，靶向 Hepcidin-25。Anti-Hepcidin-25 Antibody (7S819) 可用于 WB。

Anti-Hepcidin-25 Antibody (7S819)

Anti-Hepcidin-25 Antibody (7S819)

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Rating icon 还可以
货号 TMAB-06979

Anti-Hepcidin-25 Antibody (7S819) 是一种 Rabbit 抗体，靶向 Hepcidin-25。Anti-Hepcidin-25 Antibody (7S819) 可用于 WB。

规格价格库存数量
25 μL
¥ 790
5日内发货
50 μL
¥ 1,385
5日内发货
100 μL
¥ 2,495
5日内发货
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产品介绍

生物活性
产品描述
Anti-Hepcidin-25 Antibody (7S819) is a Rabbit antibody targeting Hepcidin-25. Anti-Hepcidin-25 Antibody (7S819) can be used in WB.
Ig Type
IgG
克隆号
7S819
反应种属
Human,Rat
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Secreted.
组织特异性Highest expression in liver and to a lesser extent in heart and brain. Low levels in lung, tonsils, salivary gland, trachea, prostate gland, adrenal gland and thyroid gland. Secreted into the urine.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景Hepcidin, also known as HAMP, HEPC, LEAP1 or HFE2B, is an 84 amino acid secreted protein that regulates iron-related signaling events. Acts by promoting endocytosis and degradation of ferroportin, leading to the retention of iron in iron-exporting cells and decreased flow of iron into plasma.
抗原信息
免疫原
A synthesized peptide: human Hepcidin
抗原种属
Human
基因名称
HAMP
基因ID
57817
蛋白名称
Hepcidin
Uniprot ID
P81172
功能
Seems to act as a signaling molecule involved in the maintenance of iron homeostasis. Seems to be required in conjunction with HFE to regulate both intestinal iron absorption and iron storage in macrophages.
Has strong antimicrobial activity against E.coli ML35P N.cinerea and weaker against S.epidermidis, S.aureus and group b streptococcus bacteria. Active against the fungus C.albicans. No activity against P.aeruginosa.
Involvement in disease;Defects in HAMP are the cause of hemochromatosis type 2B (HFE2B); also known as juvenile hemochromatosis (JH). HFE2B is a disorder of iron metabolism with excess deposition of iron in the tissues, bronze skin pigmentation, hepatic cirrhosis, arthropathy and diabetes. The most common symptoms of hemochromatosis type 2 at presentation are hypogonadism and cardiomyopathy.
化学信息
分子量Theoretical: 9 kDa. Actual: 25 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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