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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-GPR7 Polyclonal Antibody

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货号 TMAB-06728

Anti-GPR7 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 GPR7。Anti-GPR7 Polyclonal Antibody 可用于 WB。

Anti-GPR7 Polyclonal Antibody

Anti-GPR7 Polyclonal Antibody

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货号 TMAB-06728

Anti-GPR7 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 GPR7。Anti-GPR7 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-GPR7 Polyclonal Antibody is a Rabbit antibody targeting GPR7. Anti-GPR7 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Mouse (predicted:Human)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell membrane; Multipass membrane protein.
组织特异性Expressed at high levels in brain and spinal cord and at detectable levels in retinal pigment epithelium. In situ hybridization of adult eye sections localized transcripts only to the perivascular cells, surrounding retinal arterioles, in the ganglion cell/nerve fiber layer.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The two G protein-coupled receptors GPR7 and GPR8 display high similarity to each other. They both show high expression in brain and in particular in hypothalamus, and have been characterized as receptors for neuropeptide W (NPW) and neuropeptide B (NPB). In response to NPW and NPB, they play a role in the regulation of feeding behavior. GPR7 deficient mice develop an adult-onset obese phenotype that progressively worsens with age and is exacerbated when fed a high-fat diet. The genes encoding human GPR7 and GPR8 map to chromosomes 10q11.2-q21.1 and 10q13.3, respectively.
抗原信息
免疫原
KLH conjugated synthetic peptide: human GPR7
抗原种属
Human
基因名称
GPR75
基因ID
10936
蛋白名称
Probable G-protein coupled receptor 75
Uniprot ID
O95800
功能
GPR7 interacts specifically with a number of opioid ligands. It is a receptor for neuropeptides B and W, which may be involved in neuroendocrine system regulation, food intake and the organization of other signals, and has a higher affinity for neuropeptide B. It has been reported in brain, mainly cerebellum and frontal cortex, and in the pituitary (O'Dowd et al., 1995). The mouse ortholog of GPR7 was shown by in situ hybridization to be expressed in discrete nuclei of brain, namely suprachiasmatic, arcuate, and ventromedial nuclei of hypothalamus.
化学信息
分子量Theoretical: 59 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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