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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-COREST Antibody (5R620)

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货号 TMAB-04586

Anti-COREST Antibody (5R620) 是一种 Rabbit 抗体，靶向 COREST。Anti-COREST Antibody (5R620) 可用于 IHC-P,IHC-Fr,ICC/IF,IF,FCM。

Anti-COREST Antibody (5R620)

Anti-COREST Antibody (5R620)

一键复制产品信息
Rating icon 还可以
货号 TMAB-04586

Anti-COREST Antibody (5R620) 是一种 Rabbit 抗体，靶向 COREST。Anti-COREST Antibody (5R620) 可用于 IHC-P,IHC-Fr,ICC/IF,IF,FCM。

规格价格库存数量
25 μL
¥ 780
5日内发货
50 μL
¥ 1,385
5日内发货
100 μL
¥ 2,495
5日内发货
库存状态实时更新，以官网显示为准，现货产品可直接加购物车下单
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产品介绍

生物活性
产品描述
Anti-COREST Antibody (5R620) is a Rabbit antibody targeting COREST. Anti-COREST Antibody (5R620) can be used in IHC-P,IHC-Fr,ICC/IF,IF,FCM.
Ig Type
IgG
克隆号
5R620
反应种属
Human (predicted:Mouse,Rat)
应用IHC-PIHC-FrICC/IFIFFCM
推荐剂量
IHC-P: 1:50-200; IHC-Fr: 1:50-200; ICC/IF: 1:50-200; IF: 1:50-200; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Nucleus. Upon infection by HSV-1, it is partially translocated into the cytoplasm in an HSV-1-dependent manner.
组织特异性Ubiquitously expressed.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景Essential component of the BHC complex, a corepressor complex that represses transcription of neuron-specific genes in non-neuronal cells. The BHC complex is recruited at RE1/NRSE sites by REST and acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier. In the BHC complex, it serves as a molecular beacon for the recruitment of molecular machinery, including MeCP2 and SUV39H1, that imposes silencing across a chromosomal interval.
抗原信息
免疫原
A synthesized peptide: human REST corepressor 1
抗原种属
Human
基因名称
RCOR1
基因ID
23186
蛋白名称
REST corepressor 1
Uniprot ID
Q9UKL0
功能
Essential component of the BHC complex, a corepressor complex that represses transcription of neuron-specific genes in non-neuronal cells. The BHC complex is recruited at RE1/NRSE sites by REST and acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier. In the BHC complex, it serves as a molecular beacon for the recruitment of molecular machinery, including MeCP2 and SUV39H1, that imposes silencing across a chromosomal interval. Plays a central role in demethylation of Lys-4 of histone H3 by promoting demethylase activity of KDM1A on core histones and nucleosomal substrates. It also protects KDM1A from the proteasome.
化学信息
分子量Theoretical: 53 kDa. Actual: 66 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

  • 稀释 计算器
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