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Anti-BCL2 Polyclonal Antibody 3

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Anti-BCL2 Polyclonal Antibody 3
产品编号 TMAB-00198

Anti-BCL2 Polyclonal Antibody 3 是一种 Rabbit 抗体,靶向 BCL2。Anti-BCL2 Polyclonal Antibody 3 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF,ELISA。

Anti-BCL2 Polyclonal Antibody 3

Anti-BCL2 Polyclonal Antibody 3

Rating icon 还可以
Anti-BCL2 Polyclonal Antibody 3
产品编号 TMAB-00198

Anti-BCL2 Polyclonal Antibody 3 是一种 Rabbit 抗体,靶向 BCL2。Anti-BCL2 Polyclonal Antibody 3 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF,ELISA。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,970
5日内发货
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产品介绍

生物活性
产品描述
Anti-BCL2 Polyclonal Antibody 3 is a Rabbit antibody targeting BCL2. Anti-BCL2 Polyclonal Antibody 3 can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,ELISA.
Ig Type
IgG
交叉反应
Human,Mouse,Rat
验证活性
Sample:
Lane 1: Spleen (Mouse) Lysate at 40 μg
Lane 2: LympHnode (Mouse) Lysate at 40 μg
Lane 3: LympHnode (Rat) Lysate at 40 μg
Lane 4: MCF-7 (Human) Cell Lysate at 30 μg
Lane 5: SiHa (Human) Cell Lysate at 30 μg
Lane 6: Jurkat (Human) Cell Lysate at 30 μg
Lane 7: A431 (Human) Cell Lysate at 30 μg
Lane 8: Bone (Rat) Lysate at 40 μg
Lane 9: Bone (Mouse) Lysate at 40 μg
Lane 10: A549 (Human) Cell Lysate at 30 μg
Lane 11: SH-SY5Y (Human) Cell Lysate at 30 μg
Primary: Anti-Bcl-2 (TMAB-00198) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 26 kDa
Observed band size: 26 kDa
应用
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-300; ICC/IF: 1:100-500; IF: 1:200-1000; ELISA: 1:10000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Mitochondrion outer membrane; Single-pass membrane protein. Nucleus membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Proclin300.
研究背景The Bcl-2 gene was isolated at the chromosomal breakpoint of t(14;18)-bearing follicular B cell lymphomas(1,2).Bcl-2 blocks cell death following a variety of stimuli and confers a death-sparing effect to certain hematopoietic cell lines following growth factor withdrawal (3,5).Bcl-2 appears to function in several subcellular locations yet lacks any known motifs that would confer insight into its mechanism of action (6,7).A more recently identified protein,designated Bax p21(i.e., Bcl-associated X protein ),has extensive amino acid homology with Bcl-2 and both homodimerizes and forms heterodimers with Bcl-2(8). Overexpression of Bax accelerates apoptotic death induced by cytokine deprivation in an IL-3 dependent cell line and Bax also counters the death repressor activty of Bcl-2(8).
抗原信息
免疫原
KLH conjugated synthetic peptide: human Bcl-2
抗原种属
Human
基因ID
Uniprot ID
研究领域
Cellular metabolic process,Response to hypoxia,Bcl 2 family,Metabolism,Bcl 2 family,Cell survival & death,Oncoproteins,Bcl2 Family,Apoptosis marker and proteins ELISA kits,Apoptosis,Hypoxia,Mitochondrial markers,Cancer,Mitochondrial
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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