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VH032-PEG5-C6-Cl (HaloPROTAC 2) is a small molecule HaloPROTAC that incorporates the VH032 based VHL ligand and 5-unit PEG linker. VH032-PEG5-C6-Cl is capable of inducing the degradation of GFP-HaloTag7 in cell-based assays[1].

Boc-C5-O-C5-O-C6-Cl (PROTAC Linker 2) is a chemical compound commonly employed as a linker in PROTAC applications. Its primary function is to connect a specific tyrosine kinase inhibitor (TKI) with the E3 recruiting ligand.

5-Br-4-Cl-Pyrrolo-pyroxypyridine，一种用于PROTAC靶蛋白配体（Ligands for Target Protein for PROTACs）的化合物，具有合成应用。

2-MSP-5-HA-GGFG-NH-CH2-O-CH2-CO-(5-Cl)-Exatecan 是一种用于 ADC 的药物-linker 偶联物，由 linker 和 Exatecan 组成。

Thalidomide-5-PEG2-Cl, a Thalidomide-derived cereblon ligand, serves as the ligand for the recruitment of CRBN protein. It can be conjugated to the protein ligand via a linker to produce PROTACs.

(5-Cl)-Exatecan (compound 1-5) 作为一种ADC细胞毒素，主要用于癌症研究。它是一种高效的DNA拓扑异构酶抑制剂。

NH2-PEG5-C6-Cl (K-7) is a PROTAC linker characterized by its PEG composition. It can be utilized in the synthesis of various PROTACs, facilitating the degradation of intracellular molecules via autophagy[1].

NH2-PEG5-C6-Cl hydrochloride is a polyethylene glycol (PEG)-based linker compound, commonly employed in the synthesis of proteolysis targeting chimeras (PROTACs).

CL845-PAB-Ala-Val-C5-MC 是一种可结合的 STING 配体，由专有的环状二核苷酸 CL845 合成。CL845-PAB-Ala-Val-C5-MC 可用于生物偶联。

Zolamide (CL 5343) 可用于预防高原反应和减轻症状。

LCL521 能抑制溶酶体酸性鞘磷脂酶（ASMase）。LCL521 是一种酸性神经酰胺酶(ACDase)抑制剂。

LCL521 dihydrochloride is a compound that functions as an inhibitor of both acid ceramidase (ACDase) and lysosomal acid sphingomyelinase (ASMase).

CL-55 is a novel inhibitor of T3SS.

CL52069 is an insecticide.

A-674563 HCl (552325-73-2(free base)) 是一种口服的、ATP 竞争性的、可逆的 Akt 抑制剂（Akt1 的 Ki：11 nM）。它对 PKA 和 Cdk2 具有抑制活性（IC50：16 46 nM），但对 Akt1 的选择性比 CMGC、CAMK 和 TK 家族中的其他激酶高 10 至 >1800 倍。

A-674563 2HCl(552325-73-2(fb-2hcl)) 是一种 Akt1 抑制剂，Ki 为 11 nM，对 PKA 有效，对 Akt1 的选择性比 PKC 高 30 倍以上。

Levoleucovorin Calcium (CL307782) 是一种亚叶酸的钙盐，在癌症化疗中用作辅助剂。

Nithiamide (CL-5279) 是一种口服的抗原虫剂，用于治疗阴道滴虫病。它是非-5-硝基咪唑药物，可作兽用抗生素。

U93631 是一种具有新型化学结构的 GABAA 受体配体，IC50 为 100 nM，它在重组 GABAA 受体中诱导 GABA 诱导的全细胞 Cl 电流快速，这种效果随时间依赖性衰减。

8-Chloroadenosine (NSC-354258) 是一种 5' AMP 激活的蛋白激酶激动剂，可能用于治疗慢性淋巴细胞白血病。 它的活性与 mTOR 通路的抑制有关。它是一种核苷类似物。在体内代谢为 8-氯-ATP。在转录过程中掺入 RNA 并抑制 RNA 合成。在 MM.1S、RPMI-8226 和 U266 癌细胞系中表现出细胞毒性；在 A549 和 H1299 细胞中诱导 G2 M 细胞周期停滞和有丝分裂灾难。它已被证明可消耗 ATP 并抑制血液恶性肿瘤以及肺癌和乳腺癌细胞系中的肿瘤生长。

8-Chloro-ATP（8-Cl-cAMP），一种c-AMP的类似物，是一种新型的抗肿瘤化合物。

CL-216303 HCl, a dopamine transporter inhibitor and a 5-HT inhibitor, is used potentially for the treatment of depression.

Phenanthriplatin, also known as cis-[Pt(NH3)2-(phenanthridine)Cl]NO3, is a new drug candidate. It belongs to a family of platinum(II)-based agents which includes cisplatin, oxaliplatin and carboplatin. Phenanthriplatin Acts As a Covalent Poison of Topoiso

YW3-56 is a potent peptidylarginine deiminase (PAD) inhibitor, with an IC50 of 1-5 μM for PAD4. Compared with Cl-amidine, YW3-56 shows >60-fold increase in cell growth inhibition efficacy (IC50 about 2.5 μM) but only 5-fold increase in PAD4 inhibition (IC sub>50 about 1-5 μM). At 2-4 μM concentrations, YW3-56 displays mainly cytostatic effects by slowing cell division, whereas at higher concentrations, it exerts cytotoxic effects by altering cell morphology and killing cells[1]. [1]. Wang Y, et al. Anticancer peptidylarginine deiminase (PAD) inhibitors regulate the autophagy flux and t he mammalian target of rapamycin complex 1 activity. J Biol Chem. 2012 Jul 27;287(31):25941-53.