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Targets Recommended: Complement System

61

抑制剂 & 化合物

8

天然产物

2

化合物库

230

重组蛋白

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Cat. No. Product Name
L7860 Mini片段亲电杂环化合物库

369 compounds
高溶解度共价杂环片段库中的 369 个化合物
L2140 癌细胞分化化合物库

413 compounds
413 个诱导肿瘤细胞分化化合物的独特集合,可用于高通量筛选和高内涵筛选;

化合物库

Mini片段亲电杂环化合物库
Cat.No: L7860
Compounds: 369
癌细胞分化化合物库
Cat.No: L2140
Compounds: 413
Cat. No. Product Name Target Signaling Pathways
T9189 Iptacopan hydrochloride

Iptacopan HCl,LNP023 hydrochloride

Complement System Immunology/Inflammation
Iptacopan hydrochloride (LNP023 hydrochloride) 是一种可口服、高效和高选择性的因子 B 抑制剂,IC50 为 10 nM。 LNP023 显示与人因子 B 的直接、可逆和高亲和力结合,KD 为 7.9 nM。
T9854 HIV-1 inhibitor-6 

3-Pyridinecarboxamide, 1,4-dihydro-1-methyl-N-(5-nitro-1,2-benzisothiazol-3-yl)-4-oxo-

HIV Protease Microbiology/Virology; Proteases/Proteasome
HIV-1 inhibitor-6 (3-Pyridinecarboxamide, 1,4-dihydro-1-methyl-N-(5-nitro-1,2-benzisothiazol-3-yl)-4-oxo-) 是一种有效的HIV-1 pre-mRNA 选择性剪接抑制剂,可以阻断HIV 复制。
TP1869L Antioxidant peptide A acetate

Antioxidant peptide A acetate (159147-88-3 free base)

Others Others
Antioxidant peptide A acetate (159147-88-3 free base) 是一种短肽,它含有替代的芳香族或含硫氨基酸。
T9508 MONOCAPRYLIN

Sefsol 318,Glyceryl monocaprylate,辛酸甘油酯

Antibacterial Microbiology/Virology
Monocaprylin (Sefsol 318) 是一种辛酸甘油单辛酸酯,有出色的抗菌活性,可抑制多种食源性致病和腐败微生物,有用于替代食品防腐剂的研究潜力。
T7593 Levomefolate calcium

左旋甲状腺素钙,L-5-甲基四氢叶酸钙

Antifolate Cell Cycle/Checkpoint
Levomefolate calcium 是一种人工形式的叶酸。它是叶酸的一种辅酶形式,是膳食补充剂中生物利用度更高的替代品。
T6853 GSK591

GSK3203591,EPZ015866

Histone Methyltransferase Chromatin/Epigenetic
GSK591 (GSK3203591) 是一种有效的精氨酸甲基转移酶 PRMT5 选择性抑制剂,IC50值为 11 nM。
T1254 Chlorophyllin sodium copper salt

Chlorophyllin copper sodium complex,Chlorophyllin,叶绿素铜钠盐,Chlorophyllin coppered trisodium salt,Sodium-copper chlorin e6

Others Others
Chlorophyllin sodium copper salt (Chlorophyllin coppered trisodium salt) 是一种由 Chlorophyll 衍生的铜钠盐的半合成混合物,常用作食品添加剂。
T5593 L-Alanyl-L-glutamine

L-丙氨酰-L-谷氨酰胺,L-丙氨酸-L-谷氨酰胺,Ala-Gln

Others; Endogenous Metabolite Metabolism; Others
L-Alanyl-L-glutamine (Ala-Gln) 是一种由丙氨酸和谷氨酰胺组成的二肽,对抗氧化系统有益,能够减轻炎症,并能够在分解代谢情况下调节热休克蛋白 (HSP) 的反应。
T14226 Amino-PEG11-amine

氨基-十二聚乙二醇-氨基

Others; PROTAC Linker Others; PROTAC
Amino-PEG11-amine 是一种基于 PEG(12 个单位)的 PROTAC 接头,能够结合两种基于单乙基雌酚的配体,是制备用于乳腺癌内分泌治疗的更具选择性和活性的 ER 拮抗剂的替代策略。
T61354 Fosphenytoin

Others Others
Fosphenytoin 是一种磷酸酯前药,可替代静脉注射苯妥英,用于急性干预癫痫发作。Fosphenytoin 在肠胃外给药可水解成具有抗惊厥作用的苯妥英。Fosphenytoin 可用于多种给药方式,如静脉注射和腹腔注射。
T9682 AZD-4877

AZD4877

Apoptosis; Kinesin Apoptosis; Cytoskeletal Signaling
AZD-4877 是一种高效的纺锤体驱动蛋白 (Eg5) 抑制剂,对其 IC50 值为 2 nM。 AZD-4877 是 Ispinesib 的另一种构型, 能够抑制细胞有丝分裂,诱导形成单极纺锤体表型,介导细胞凋亡(Apoptosis)。 AZD-4877 具有抗肿瘤活性,对循环外周血单核细胞 (PBMC)有抑制作用。
T4570 Pipobroman

Vercyte,A-8103,Amedel,哌泊溴烷

Others; DNA Alkylator/Crosslinker DNA Damage/DNA Repair; Others
Pipobroman (Vercyte) 是一种烷基化剂,是哌嗪的溴化衍生物。它通过抑制 DNA 和 RNA 聚合酶或减少嘧啶核苷酸掺入 DNA 发挥其作用。它在真性红细胞增多症和原发性血小板增多症中具有良好的临床活性,可用于癌症研究。
T19476 NHC-triphosphate

Others Others
NHC-triphosphate is a weak alternative substrate for the viral polymerase and changes the mobility of the product in polyacrylamide electrophoresis gels.
T19482 Norbiotinamine

Others Others
Norbiotinamine is an alternative to biotin.
T19481 Norbiotinamine hydrochloride

Others Others
Norbiotinamine hydrochloride is an alternative to biotin.
T20316 Calcium stearate

AI3 01335,AI3-01335,AI301335

Calcium Stearate is a potent Alternative to Poly(vinyl alcohol) in Poly-Lactic-co-Glycolic Acid Nanoparticles Synthesis.
TD0009 Sulfo-Cy3 diacid

Cy3双酸

Sulfo-Cyanine 3 is an alternative dye primarily used for labeling peptides and oligos in replacing Cy5 that was originally developed by GE Healthcare.
TP1869 Antioxidant peptide A

Antioxidant peptide A is a short peptide, which contains alternative aromatic or sulfur-containing amino acid.
T34270 Razupenem

SMP601,SMP 601,PTZ601,PTZ 601,PTZ-601,SMP-601

Razupenem ( SMP-601, PTZ601) is a broad-spectrum injectable antibiotic derived from the carbapenem subgroup of β-lactam antibiotics. It has been developed as an alternative drug against bacteria that have developed antibiotic resistance to commonly used a
T69313 Ascofuranone

Ascofuranone is an inhibitor of the ubiquinol oxidase activity of Trypanosoma brucei mitochondrial alternative oxidase (TAO), as well as an inhibitor of HsDHODH.
T19979 Saccharin sodium hydrate

O-benzoic sulfimide sodium salt,糖精钠,Saccharin, sodium salt hydrate

Saccharin, sodium salt hydrate is used in the food industry and for sweetening diabetes diet. It is also used as a synthetic sweet ignorance agent. Saccharin, sodium salt hydrate is the first generation′ synthetic sugar alternative that has been studied f
TD0010 Sulfo-Cy3 diacid, SE

Cy3双酸-N-羟基琥珀酰亚胺酯

Sulfo-Cyanine 3 is an alternative dye primarily used for labeling peptides and oligos in replacing Cy6 that was originally developed by GE Healthcare.
TD0062 6-CR110 [6-Carboxyrhodamine 110] *Single isomer*

6-羧基罗丹明110(单一化合物)

Compared to fluorescein labeling reagents such as FITC and FAM, CR110 reagents give more photostable and pH-independent bioconjugates that have the absorption maximum around the preferred 488 nm excitation wavelength. They are photostable alternative reagents superior to FITC and FAM.
TD0060 5(6)-CR110 [5-(and 6)-Carboxyrhodamine 110] *Mixed isomers*

5(6)-羧基罗丹明110(混合物)

Compared to fluorescein labeling reagents such as FITC and FAM, CR110 reagents give more photostable and pH-independent bioconjugates that have the absorption maximum around the preferred 488 nm excitation wavelength. They are photostable alternative reagents superior to FITC and FAM.
TD0061 5-CR110 [5-Carboxyrhodamine 110] *Single isomer*

5-羧基罗丹明110(单一化合物)

Compared to fluorescein labeling reagents such as FITC and FAM, CR110 reagents give more photostable and pH-independent bioconjugates that have the absorption maximum around the preferred 488 nm excitation wavelength. They are photostable alternative reag
TD0008 Sulfo-Cy3 cadaverine

Cy3,尸胺

Sulfo-Cyanine 3 is an alternative dye primarily used for labeling peptides and oligos in replacing Cy4 that was originally developed by GE Healthcare.
TD0007 Sulfo-Cy3 ethylenediamine

Cy3, 乙二胺

Sulfo-Cyanine 3 is an alternative dye primarily used for labeling peptides and oligos in replacing Cy3 that was originally developed by GE Healthcare.
TD0063 5(6)-CR110, SE [5-(and 6)-Carboxyrhodamine 110, succinimidyl ester] *Mixed isomers*

5(6)-羧基罗丹明110琥珀酰亚胺酯(混合物)

Compared to fluorescein labeling reagents such as FITC and FAM, CR110 reagents give more photostable and pH-independent bioconjugates that have the absorption maximum around the preferred 488 nm excitation wavelength. They are photostable alternative reagents superior to FITC and FAM.
T11269 FD-IN-1

Others Others
FD-IN-1 is a factor D (FD) inhibitor with an IC50 of 12 nM.FD-IN-1 also inhibits factor XIa (FXIa) and Tryptase β2 with IC50s of 7.7 and 6.5μM, respectively. Complement FD, a highly specific S1 serine protease, plays a central role in the alternative complement pathway of the innate immune system.
TP2032 des-​Gln14-​Ghrelin

des-Gln14-Ghrelin (rat)

An endogenous ligand for the ghrelin receptor (GHS-R1a), produced by alternative splicing of the rat ghrelin gene. Potently induces Ca2+ release in cells expressing ghrelin receptors (EC50 = 2.4 nM) and stimulates GH release in vivo.
T10221L Abeprazan

DWP14012

Others Others
Abeprazan (DWP14012) is a potassium-competitive acid blocker and it is developed as a potential alternative to proton pump inhibitor for the treatment of acid-related diseases[1]. Abeprazan inhibits H+, K+- ATPase by reversible potassium-competitive ionic
TD0065 6-CR110, SE [6-Carboxyrhodamine 110, succinimidyl ester]*Single isomer*

6-羧基罗丹明110琥珀酰亚胺酯(单一化合物)

Compared to fluorescein labeling reagents such as FITC and FAM, CR110 reagents give more photostable and pH-independent bioconjugates that have the absorption maximum around the preferred 488 nm excitation wavelength. They are photostable alternative reagents superior to FITC and FAM.
T81826 Meayamycin D

Meayamycin D, 作为FR901464的类似物,能够诱导MCL-1的选择性剪接,并在小鼠血浆中展现出较长的半衰期。
TD0064 5-CR110, SE [5-Carboxyrhodamine 110, succinimidyl ester]*Single isomer*

5-羧基罗丹明110琥珀酰亚胺酯(单一化合物)

Compared to fluorescein labeling reagents such as FITC and FAM, CR110 reagents give more photostable and pH-independent bioconjugates that have the absorption maximum around the preferred 489 nm excitation wavelength. They are photostable alternative reag
T14223 Amino-PEG10-amine

Others Others
Amino-PEG10-amine is a PEG-based PROTAC linker employed for the conjugation of two mono diethylstilbestrol (DES)-based ligands. This compound offers an alternative approach to the synthesis of highly selective and active ER antagonists, which are crucial for the advancement of endocrine therapy in breast cancer treatment[1].
T39656 BDY FL-X, SE

BODIPY FL-X,SE is a fluorescent green dye for the labeling of amine , shows a high fluorescence quantum yield and is relatively insensitive to pH change. BODIPY FL-X,SE can be used as an alternative for FAM, Cy2 or FITC. λ abs : 504 nm; λ em :510 nm.
T82906 BDP FL maleimide

BDP FL maleimide为一硫醇反应性染料(Ex: 503 nm;Em: 509 nm)。适用于蛋白质标记及肽修饰,亦可作为荧光素(FAM)替代品于显微镜下观察使用。
T36304 Fluorescein-NAD+

Fluoroscein NAD+ is a substrate for ADP-ribosylation, providing a convenient non-isotopic alternative to radiolabelled NAD for use in PARP assays. Allows direct measurement of NAD-dependent enzymes, such as PARP, by fluorescence microscopy. This product is a replacement for R&D Systems product 4673-500-01 81 μg is supplied as 250 μl of a 0.25 mM solution in water.
T81912 LSP-GR3

iGluR Membrane transporter/Ion channel; Neuroscience
LSP-GR3为一种新型化学修饰RNA寡核苷酸,亦即剪接调控寡聚体(SMOs),可特异性调控中枢神经系统内GluR的选择性剪接及GluR3-flip表达。
T68957 Eprociclovir dihydrate

Eprociclovir dihydrate is a new acyclovir analogue and a potent inhibitor of EHV1 replication and may have potential for the treatment and/or prophylaxis of infections with this virus. Eprociclovir possess potent anti-herpetic activity against most human herpesviruses. A-5021 proved to be about 15-fold more potent than acyclovir in inhibiting viral replication. Eprociclovir inhibits murine herpetic keratitis. A-5021 eyedrops, which are easily applied onto the affected cornea, ameliorated clinica...
T70642 Lanopepden camsylate

Lanopepden, also known as GSK-1322322 or GSK-322, is a potent and selective peptide deformylase inhibitor with good in vitro activity against bacteria associated with community-acquired pneumonia and skin infections. GSK1322322 had bactericidal activity against S. pneumoniae, H. influenzae, S. pyogenes, and S. aureus, demonstrating a ≥ 3-log(10) decrease in the number of CFU/ml at 4× MIC within 24 h in 29 of the 33 strains tested. GSK1322322 represents a valuable alternative therapy for the trea...
T69817 Eprociclovir Na

Eprociclovir Na is the salt form of Eprociclovir, also known as A-5021, a new acyclovir analogue and a potent inhibitor of EHV1 replication and may have potential for the treatment and/or prophylaxis of infections with this virus. Eprociclovir possess potent anti-herpetic activity against most human herpesviruses. A-5021 proved to be about 15-fold more potent than acyclovir in inhibiting viral replication. Eprociclovir inhibits murine herpetic keratitis. A-5021 eyedrops, which are easily applie...
T76071 Epinecidin-1 TFA

Epinecidin-1 TFA 是从橙斑石斑鱼 (Epinephelus coioides) 得到的的多功能抗菌肽 (AMP)。Epinecidin-1 TFA 具有抗菌、抗真菌、抗病毒、抗肿瘤和免疫调节作用。Epinecidin-1 TFA 可能成为目前抗生素的替代试剂。
T81356 PTBP1-RNA-binding inhibitor P6 TFA

PTBP1 α3-helix derived peptide P6 TFA

PTBP1-RNA-binding inhibitor P6 (PTBP1 α3-helix derived peptide P6) TFA 为剪接因子PTBP1的特定钉合肽抑制剂,用于抑制PTBP1调控的RNA选择性剪接事件。该抑制剂通过与PTBP1的RNA识别基序相结合,从而发挥其作用。
T76814 Lampalizumab

Lampalizumab (RG 7417) 是一种人源单克隆抗体,靶向补体通路中的补体因子 D (Factor D)。Lampalizumab 可结合外位点,立体阻断因子 B 进入活性位点。Lampalizumab 可用于老年性黄斑变性 (AMD) 研究。
T74070 NHC-triphosphate tetrasodium

NHC-triphosphate tetrasodium 是 NHC 的活性胞内磷酸盐代谢物 (intracellular metabolite),以三磷酸盐的形式存在。NHC-triphosphate tetrasodium 是病毒聚合酶 (viral polymerase) 的弱底物替代物,会被并入HCV 复制子 RNA 中。
T37756 Phloxine B

Phloxine B is a red dye, the USP grade of which is used as a color additive for food, drugs, and cosmetics. It has also been used as an alternative to Gram staining, to differentiate between Gram-negative and Gram-positive bacteria. At 100 μg/ml, it can inhibit methicillin-resistant S. aureus growth in vitro. Phloxine B has also been shown to modulate channel activity of wild-type cystic fibrosis transmembrane conductance regulator chloride channels (CFTR; Ki = 38 μM) and mutant delta F508 CFTR ...
T70027 Eprociclovir potassium

Eprociclovir potassium is a new acyclovir analogue and a potent inhibitor of EHV1 replication and may have potential for the treatment and/or prophylaxis of infections with this virus. Eprociclovir possess potent anti-herpetic activity against most human herpesviruses. A-5021 proved to be about 15-fold more potent than acyclovir in inhibiting viral replication. Eprociclovir inhibits murine herpetic keratitis. A-5021 eyedrops, which are easily applied onto the affected cornea, ameliorated clinica...
T36881 NHC-diphosphate triammonium

NHC-triphosphate triammonium is an active phosphorylated intracellular metabolite of β-d-N4-Hydroxycytidine (NHC) as a triphosphate form[1]. NHC-triphosphate triammonium is a weak alternative substrate for the viral polymerase and can be incorporated into HCV replicon RNA[1][2]. In an intracellular metabolism assay, HCV replicon cells are treated with 10 μM 3H-labeled NHC, and intracellular nucleotide levels are determined after 1, 2 and 8 hours incubations. NHC is rapidly convered into the mono...
T60369 Droxidopa hydrochloride

Droxidopa (L-DOPS) hydrochloride 是一种有效的、具有口服活性的去甲肾上腺素前体。Droxidopa hydrochloride 可增加站立血压,改善直立性低血压症状并提高站立能力。Droxidopa hydrochloride 具有研究神经源性直立性低血压(nOH)和替代性多动症 (注意缺陷多动障碍) 的潜力[3]。

化合物

Iptacopan hydrochloride
Cat.No: T9189
Synonym: Iptacopan HCl,LNP023 hydrochloride
Target: Complement System
HIV-1 inhibitor-6 
Cat.No: T9854
Synonym: 3-Pyridinecarboxamide, 1,4-dihydro-1-methyl-N-(5-nitro-1,2-benzisothiazol-3-yl)-4-oxo-
Target: HIV Protease
Antioxidant peptide A acetate
Cat.No: TP1869L
Synonym: Antioxidant peptide A acetate (159147-88-3 free base)
Target: Others
MONOCAPRYLIN
Cat.No: T9508
Synonym: Sefsol 318,Glyceryl monocaprylate,辛酸甘油酯
Target: Antibacterial
Levomefolate calcium
Cat.No: T7593
Synonym: 左旋甲状腺素钙,L-5-甲基四氢叶酸钙
Target: Antifolate
GSK591
Cat.No: T6853
Synonym: GSK3203591,EPZ015866
Target: Histone Methyltransferase
Chlorophyllin sodium copper salt
Cat.No: T1254
Synonym: Chlorophyllin copper sodium complex,Chlorophyllin,叶绿素铜钠盐,Chlorophyllin coppered trisodium salt,Sodium-copper chlorin e6
Target: Others
L-Alanyl-L-glutamine
Cat.No: T5593
Synonym: L-丙氨酰-L-谷氨酰胺,L-丙氨酸-L-谷氨酰胺,Ala-Gln
Target: Others, Endogenous Metabolite
Amino-PEG11-amine
Cat.No: T14226
Synonym: 氨基-十二聚乙二醇-氨基
Target: Others, PROTAC Linker
Fosphenytoin
Cat.No: T61354
Synonym:
Target: Others
AZD-4877
Cat.No: T9682
Synonym: AZD4877
Target: Apoptosis, Kinesin
Pipobroman
Cat.No: T4570
Synonym: Vercyte,A-8103,Amedel,哌泊溴烷
Target: Others, DNA Alkylator/Crosslinker
NHC-triphosphate
Cat.No: T19476
Synonym:
Target: Others
Norbiotinamine
Cat.No: T19482
Synonym:
Target: Others
Norbiotinamine hydrochloride
Cat.No: T19481
Synonym:
Target: Others
Calcium stearate
Cat.No: T20316
Synonym: AI3 01335,AI3-01335,AI301335
Target:
Sulfo-Cy3 diacid
Cat.No: TD0009
Synonym: Cy3双酸
Target:
Antioxidant peptide A
Cat.No: TP1869
Synonym:
Target:
Razupenem
Cat.No: T34270
Synonym: SMP601,SMP 601,PTZ601,PTZ 601,PTZ-601,SMP-601
Target:
Ascofuranone
Cat.No: T69313
Synonym:
Target:
Saccharin sodium hydrate
Cat.No: T19979
Synonym: O-benzoic sulfimide sodium salt,糖精钠,Saccharin, sodium salt hydrate
Target:
Sulfo-Cy3 diacid, SE
Cat.No: TD0010
Synonym: Cy3双酸-N-羟基琥珀酰亚胺酯
Target:
6-CR110 [6-Carboxyrhodamine 110] *Single isomer*
Cat.No: TD0062
Synonym: 6-羧基罗丹明110(单一化合物)
Target:
5(6)-CR110 [5-(and 6)-Carboxyrhodamine 110] *Mixed isomers*
Cat.No: TD0060
Synonym: 5(6)-羧基罗丹明110(混合物)
Target:
5-CR110 [5-Carboxyrhodamine 110] *Single isomer*
Cat.No: TD0061
Synonym: 5-羧基罗丹明110(单一化合物)
Target:
Sulfo-Cy3 cadaverine
Cat.No: TD0008
Synonym: Cy3,尸胺
Target:
Sulfo-Cy3 ethylenediamine
Cat.No: TD0007
Synonym: Cy3, 乙二胺
Target:
5(6)-CR110, SE [5-(and 6)-Carboxyrhodamine 110, succinimidyl ester] *Mixed isomers*
Cat.No: TD0063
Synonym: 5(6)-羧基罗丹明110琥珀酰亚胺酯(混合物)
Target:
FD-IN-1
Cat.No: T11269
Synonym:
Target: Others
des-​Gln14-​Ghrelin
Cat.No: TP2032
Synonym: des-Gln14-Ghrelin (rat)
Target:
Abeprazan
Cat.No: T10221L
Synonym: DWP14012
Target: Others
6-CR110, SE [6-Carboxyrhodamine 110, succinimidyl ester]*Single isomer*
Cat.No: TD0065
Synonym: 6-羧基罗丹明110琥珀酰亚胺酯(单一化合物)
Target:
Meayamycin D
Cat.No: T81826
Synonym:
Target:
5-CR110, SE [5-Carboxyrhodamine 110, succinimidyl ester]*Single isomer*
Cat.No: TD0064
Synonym: 5-羧基罗丹明110琥珀酰亚胺酯(单一化合物)
Target:
Amino-PEG10-amine
Cat.No: T14223
Synonym:
Target: Others
BDY FL-X, SE
Cat.No: T39656
Synonym:
Target:
BDP FL maleimide
Cat.No: T82906
Synonym:
Target:
Fluorescein-NAD+
Cat.No: T36304
Synonym:
Target:
LSP-GR3
Cat.No: T81912
Synonym:
Target: iGluR
Eprociclovir dihydrate
Cat.No: T68957
Synonym:
Target:
Lanopepden camsylate
Cat.No: T70642
Synonym:
Target:
Eprociclovir Na
Cat.No: T69817
Synonym:
Target:
Epinecidin-1 TFA
Cat.No: T76071
Synonym:
Target:
PTBP1-RNA-binding inhibitor P6 TFA
Cat.No: T81356
Synonym: PTBP1 α3-helix derived peptide P6 TFA
Target:
Lampalizumab
Cat.No: T76814
Synonym:
Target:
NHC-triphosphate tetrasodium
Cat.No: T74070
Synonym:
Target:
Phloxine B
Cat.No: T37756
Synonym:
Target:
Eprociclovir potassium
Cat.No: T70027
Synonym:
Target:
NHC-diphosphate triammonium
Cat.No: T36881
Synonym:
Target:
Droxidopa hydrochloride
Cat.No: T60369
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T3S2105 N-Benzylpalmitamide

Macamide 1,玛卡酰胺 B,N-苄基十六烷酰胺,N-Benzylhexadecanamide

Others; FAAH; Autophagy Autophagy; Metabolism; Neuroscience; Others
N-Benzylpalmitamide (Macamide 1) 是从玛卡中得到的一种生物碱,可以时间依赖性方式抑制脂肪酸酰胺水解酶,有治疗疼痛、炎症和中枢神经系统退行性疾病的研究潜力。
T6674 L-Ascorbic acid sodium salt

(+)-Sodium L-ascorbate,Vitamin C sodium salt,Sodium ascorbate,L-Ascorbic acid sodium,抗坏血酸钠,Sodium L-ascorbate,维生素C钠

Apoptosis; Others; Calcium Channel; Reactive Oxygen Species; Endogenous Metabolite Apoptosis; Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism; NF-κB; Others
L-Ascorbic acid sodium salt (Vitamin C sodium salt) 是一种电子供体,是一种内源性抗氧化剂。它还是一种胶原沉积促进剂和弹性生成抑制剂。它选择性抑制 Cav3.2 通道(Cav3.2 channels),IC50为 6.5 μM。
T3729 Ethyl gallate

Nipagallin A,Phyllemblin,gallic acid ethyl ester,没食子酸乙酯

MMP; NF-κB; Akt; Antibacterial Cytoskeletal Signaling; Microbiology/Virology; NF-κB; PI3K/Akt/mTOR signaling; Proteases/Proteasome
Ethyl gallate (gallic acid ethyl ester) 是一种非类黄酮酚过氧化氢清除剂。
T40436 N,N'-Diacetylchitobiose

N,N'-Diacetylchitobiose, a dimer of β(1,4) linked N-acetyl-D glucosamine, is derived from the hydrolysis of chitin. This compound serves as an alternative carbon source for E. coli.
T80869 Versicolactone B

Versicolactone B,一种从Viola yedoensis分离得到的倍半萜,对经典途径和替代途径均显示出抗补体活性。
TN3070 4beta-Hydroxywithanolide E

PARP; HSP; NF-κB; COX Chromatin/Epigenetic; Cytoskeletal Signaling; DNA Damage/DNA Repair; Immunology/Inflammation; Metabolism; Neuroscience; NF-κB
4beta-Hydroxywithanolide E(4bHWE) can inhibit the growth of colon cancer monolayer and spheroid cultures, it assert its anti-tumor activity in carcinogenic progression and develop into a dietary chemopreventive agent, it affects alternative splicing by mo
TN2646 16-Hydroxycleroda-3,13-dien-15,16-olide

Autophagy Autophagy
16-Hydroxycleroda-3,13-dien-15,16-olide, and prodigiosin are presented as candidates for autophagy inducers that can trigger cell death in a supplement or alternative medicine for cancer therapy. 16-Hydroxycleroda-3,13-dien-15,16-olide regulates the expre
TN5119 Taxoquinone

Tyrosinase; Antifection Microbiology/Virology; Proteases/Proteasome
Taxoquinone has strong antibacterial effect, it could be used as a promising antibacterial agent in food industry to inhibit the growth of certain important foodborne pathogens. It (100 ug/disc) displays potential anticandidal effect against Candia albica

天然产物

N-Benzylpalmitamide
Cat.No: T3S2105
Synonym: Macamide 1,玛卡酰胺 B,N-苄基十六烷酰胺,N-Benzylhexadecanamide
Target: Others, FAAH, Autophagy
L-Ascorbic acid sodium salt
Cat.No: T6674
Synonym: (+)-Sodium L-ascorbate,Vitamin C sodium salt,Sodium ascorbate,L-Ascorbic acid sodium,抗坏血酸钠,Sodium L-ascorbate,维生素C钠
Target: Apoptosis, Others, Calcium Channel, Reactive Oxygen Species, Endogenous Metabolite
Ethyl gallate
Cat.No: T3729
Synonym: Nipagallin A,Phyllemblin,gallic acid ethyl ester,没食子酸乙酯
Target: MMP, NF-κB, Akt, Antibacterial
N,N'-Diacetylchitobiose
Cat.No: T40436
Synonym:
Target:
Versicolactone B
Cat.No: T80869
Synonym:
Target:
4beta-Hydroxywithanolide E
Cat.No: TN3070
Synonym:
Target: PARP, HSP, NF-κB, COX
16-Hydroxycleroda-3,13-dien-15,16-olide
Cat.No: TN2646
Synonym:
Target: Autophagy
Taxoquinone
Cat.No: TN5119
Synonym:
Target: Tyrosinase, Antifection
Cat. No. Product Name Species Expression System
TMPK-01074 CD163 Protein, Human, Recombinant (His & Avi)

CD163,HbSR,RM3/1,MM130,CD163 molecule,GHI/61,sCD163,SCARI1,M...

Human HEK293
The hemoglobin (Hb) scavenger receptor, CD163, is a macrophage-specific protein and the upregulated expression of this receptor is one of the major changes in the macrophage switch to alternative activated phenotypes in inflammation. Accordingly, a high CD163 expression in macrophages is a characteristic of tissues responding to inflammation.
TMPY-00399 HER3/ERBB3 Protein, Human, Recombinant

LCCS2,c-erbB-3,HER3,p180-ErbB3,erbB3-S,MDA-BF-1,erb-b2 recep...

Human HEK293
ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin binding domain but has not an active kinase domain., and therefore can not mediate the intracellular signal transduction through protein phosphorylation. However, its heterodimer with ErbB2 or other EGFR members responsible for tyrosine phosphorylation forms a receptor complex with hig...
TMPY-01389 HER3/ERBB3 Protein, Human, Recombinant (His)

MDA-BF-1,EEBB3,erbB3-S,p45-sErbB3,ErbB-3,LCCS2,p85-sErbB3,p1...

Human HEK293
ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin binding domain but has not an active kinase domain., and therefore can not mediate the intracellular signal transduction through protein phosphorylation. However, its heterodimer with ErbB2 or other EGFR members responsible for tyrosine phosphorylation forms a receptor complex with hig...
TMPY-00246 HER3/ERBB3 Protein, Rhesus, Recombinant

erb-b2 receptor tyrosine kinase 3

Rhesus HEK293
ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin binding domain but has not an active kinase domain., and therefore can not mediate the intracellular signal transduction through protein phosphorylation. However, its heterodimer with ErbB2 or other EGFR members responsible for tyrosine phosphorylation forms a receptor complex with hig...
TMPJ-00154 IL-15RA Protein, Mouse, Recombinant (hFc)(Human Cells)

sIL-15 receptor subunit α,Il15ra,Interleukin-15 receptor sub...

Mouse Human Cells
Mouse interleukin-15 receptor subunit alpha, also known as Il15ra, is a high-affinity receptor for interleukin-15. Il15ra associates as a heterotrimer with the IL-2 receptor beta and gamma subunits (Common gamma chain, or gamma c) to initiate signal transduction. It can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells. Il15ra is expressed in special cells including a wide variety of Tand B cells and non-lymphoid cells. Human Il...
TMPY-02929 ENTPD2 Protein, Human, Recombinant (aa 29-460, His)

ectonucleoside triphosphate diphosphohydrolase 2,NTPDase-2,R...

Human Baculovirus-Insect Cells
NTPDase 2, also known as ENTPD2, belongs to the ecto-nucleoside triphosphate diphosphohydrolase family (E-NTPDase). Members of E-NTPDase family are nucleotidases able to hydrolyze 5′-nucleoside tri- and/or diphosphates; the main role of these enzymes is the termination of purinergic signaling. NTPDases are ubiquitous and were previously shown in other parasites including the trypanosomatides of genus Leishmania and in T. brucei. NTPase activity would act as a timer and is crucial to T. gondii in...
TMPY-03024 HER3/ERBB3 Protein, Rat, Recombinant (His)

erb-b2 receptor tyrosine kinase 3

Rat HEK293
ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin binding domain but has not an active kinase domain., and therefore can not mediate the intracellular signal transduction through protein phosphorylation. However, its heterodimer with ErbB2 or other EGFR members responsible for tyrosine phosphorylation forms a receptor complex with hig...
TMPY-02477 HER3/ERBB3 Protein, Rhesus, Recombinant (His)

erb-b2 receptor tyrosine kinase 3

Rhesus HEK293
ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin binding domain but has not an active kinase domain., and therefore can not mediate the intracellular signal transduction through protein phosphorylation. However, its heterodimer with ErbB2 or other EGFR members responsible for tyrosine phosphorylation forms a receptor complex with hig...
TMPY-02365 HER3/ERBB3 Protein, Mouse, Recombinant (His)

Erbb-3r,Erbb3r,erb-b2 receptor tyrosine kinase 3,C76256,Erbb...

Mouse HEK293
ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin binding domain but has not an active kinase domain., and therefore can not mediate the intracellular signal transduction through protein phosphorylation. However, its heterodimer with ErbB2 or other EGFR members responsible for tyrosine phosphorylation forms a receptor complex with hig...
TMPY-04956 HER3/ERBB3 Protein, Human, Recombinant (His), Biotinylated

MDA-BF-1,c-erbB-3,HER3,p85-sErbB3,LCCS2,p180-ErbB3,erbB3-S,e...

Human HEK293
ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin binding domain but has not an active kinase domain., and therefore can not mediate the intracellular signal transduction through protein phosphorylation. However, its heterodimer with ErbB2 or other EGFR members responsible for tyrosine phosphorylation forms a receptor complex with hig...
TMPY-05538 CD16a Protein, Cynomolgus, Recombinant (His), Biotinylated

Fc fragment of IgG, low affinity IIIa, receptor (CD16a)

Cynomolgus HEK293
The Fc receptor with low affinity for IgG (FCGR3, or CD16) is encoded by 2 nearly identical genes, FCGR3A and FCGR3B, resulting in tissue-specific expression of alternative membrane-anchored isoforms. FCGR3A, it is also known as CD16a, encodes a transmembrane protein expressed on activated monocytes/macrophages, natural killer (NK) cells, and a subset of T cells. CD16a / FCGR3A is a receptor expressed on NK cells that facilitates antibody dependent cellular cytotoxicity (ADCC) by binding to the ...
TMPY-01964 CD16a Protein, Human, Recombinant (F176V, His)

FCGRIII,Fc gamma RIIIa,FCR-10,FCRIII,FCRIIIA,FCGR3,CD16A,Fc...

Human HEK293
The Fc receptor with low affinity for IgG (FCGR3, or CD16) is encoded by 2 nearly identical genes, FCGR3A and FCGR3B, resulting in tissue-specific expression of alternative membrane-anchored isoforms. FCGR3A, it is also known as CD16a, encodes a transmembrane protein expressed on activated monocytes/macrophages, natural killer (NK) cells, and a subset of T cells. CD16a / FCGR3A is a receptor expressed on NK cells that facilitates antibody dependent cellular cytotoxicity (ADCC) by binding to the...
TMPY-02018 CD16a Protein, Rat, Recombinant (His)

Fc fragment of IgG, low affinity IIIa, receptor (CD16a)

Rat HEK293
The Fc receptor with low affinity for IgG (FCGR3, or CD16) is encoded by 2 nearly identical genes, FCGR3A and FCGR3B, resulting in tissue-specific expression of alternative membrane-anchored isoforms. FCGR3A, it is also known as CD16a, encodes a transmembrane protein expressed on activated monocytes/macrophages, natural killer (NK) cells, and a subset of T cells. CD16a / FCGR3A is a receptor expressed on NK cells that facilitates antibody dependent cellular cytotoxicity (ADCC) by binding to the ...
TMPY-05345 TIGIT Protein, Cynomolgus, Recombinant (hFc)

T cell immunoreceptor with Ig and ITIM domains

Cynomolgus HEK293
TIGIT, also known as V-set and transmembrane domain-containing protein 3 (VSTM3) or V-set and immunoglobulin domain-containing protein 9 (VSIG9) is a new surface protein containing an immunoglobulin variable domain, a transmembrane domain and an immunoreceptor tyrosine-based inhibitory motif (ITIM). TIGIT is expressed on regulatory, memory, activated T cells and NK cells. It binds PVR with high affinity, and PVRL2 with lower affinity, but not PVRL3. Knockdown of TIGIT with siRNA in human memory ...
TMPY-05242 CRLF2/TSLPR Protein, Human, Recombinant (His)

CRL2,CRLF2Y,TSLPR,cytokine receptor-like factor 2

Human HEK293
Overexpression of cytokine receptor-like factor 2 (CRLF2) due to chromosomal rearrangement has been observed in acute lymphoblastic leukemia (ALL) and reported to contribute to oncogenesis and unfavorable outcome in ALL. The high CRLF2 expression works with the IKZF1 deletion to drive oncogenesis of ALL and has significance in an integrated prognostic model for adult high-risk ALL. Thymic stromal lymphopoietin (TSLP) stimulates in-vitro proliferation of human fetal B-cell precursors. However, it...
TMPY-01830 VCAM-1 Protein, Mouse, Recombinant (His)

Vcam-1,CD106,vascular cell adhesion molecule 1

Mouse HEK293
Vascular cell adhesion molecule 1 (VCAM-1), also known as CD106, is a cell surface sialoglycoprotein belonging to the immunoglobulin superfamily. Two forms of VCAM-1 with either six or seven extracellular Ig-like domains are generated by alternative splicing, with the longer form predominant. VCAM-1 is an endothelial ligand for very late antigen-4 (VLA-4) and α4ß7 integrin expressed on leukocytes, and thus mediates leukocyte-endothelial cell adhesion and signal transduction. VCAM-1 expression is...
TMPY-04970 TIGIT Protein, Human, Recombinant (hFc)

WUCAM,VSTM3,VSIG9,T cell immunoreceptor with Ig and ITIM dom...

Human HEK293
TIGIT, also known as V-set and transmembrane domain-containing protein 3 (VSTM3) or V-set and immunoglobulin domain-containing protein 9 (VSIG9) is a new surface protein containing an immunoglobulin variable domain, a transmembrane domain and an immunoreceptor tyrosine-based inhibitory motif (ITIM). TIGIT is expressed on regulatory, memory, activated T cells and NK cells. It binds PVR with high affinity, and PVRL2 with lower affinity, but not PVRL3. Knockdown of TIGIT with siRNA in human memory ...
TMPY-02669 TIGIT Protein, Mouse, Recombinant (His)

T cell immunoreceptor with Ig and ITIM domains,Vstm3,ENSMUSG...

Mouse HEK293
TIGIT, also known as V-set and transmembrane domain-containing protein 3 (VSTM3) or V-set and immunoglobulin domain-containing protein 9 (VSIG9) is a new surface protein containing an immunoglobulin variable domain, a transmembrane domain and an immunoreceptor tyrosine-based inhibitory motif (ITIM). TIGIT is expressed on regulatory, memory, activated T cells and NK cells. It binds PVR with high affinity, and PVRL2 with lower affinity, but not PVRL3. Knockdown of TIGIT with siRNA in human memory ...
TMPY-00947 VCAM-1 Protein, Human, Recombinant (hFc)

INCAM-100,CD106,VCAM-1,vascular cell adhesion molecule 1

Human HEK293
Vascular cell adhesion molecule 1 (VCAM-1), also known as CD106, is a cell surface sialoglycoprotein belonging to the immunoglobulin superfamily. Two forms of VCAM-1 with either six or seven extracellular Ig-like domains are generated by alternative splicing, with the longer form predominant. VCAM-1 is an endothelial ligand for very late antigen-4 (VLA-4) and α4ß7 integrin expressed on leukocytes, and thus mediates leukocyte-endothelial cell adhesion and signal transduction. VCAM-1 expression is...
TMPY-01803 FOLR1 Protein, Mouse, Recombinant (His)

folate receptor 1 (adult),Folbp1,FBP1,Folbp-1

Mouse HEK293
The protein encoded by FOLR1 gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transport 5-methyltetrahydrofolate into cells. This gene product is a secreted protein that either anchors to membranes via a glycosyl-phosphatidylinositol linkage or exists in a soluble form. Mutations in this gene have been associated with neurodegeneration due to cerebral folate transport deficiency. Due to the presence of two promoters, mul...
TMPY-05840 IL-1RAP/IL-1RAcP Protein, Cynomolgus, Recombinant (His)

interleukin 1 receptor accessory protein

Cynomolgus HEK293
Interleukin-1 receptor accessory protein (IL-1RAcP) also known as Interleukin-1 receptor member 3 (IL-1R3) is a cytokine receptor that binds interleukin 1. The IL-1 receptor accessory protein (IL1RAP) is a transmembrane protein that interacts with IL-1R and is required for IL-1 signal transduction. Interleukin 1 induces the synthesis of the acute phase and proinflammatory proteins during infection, tissue damage, or stress, by forming a complex at the cell membrane with an interleukin 1 receptor...
TMPY-04580 IL-1RAP/IL-1RAcP Protein, Mouse, Recombinant (His)

AI255955,6430709H04Rik,IL-1RAcP,AV239853,interleukin 1 recep...

Mouse HEK293
Interleukin-1 receptor accessory protein (IL-1RAcP) also known as Interleukin-1 receptor member 3 (IL-1R3) is a cytokine receptor that binds interleukin 1. The IL-1 receptor accessory protein (IL1RAP) is a transmembrane protein that interacts with IL-1R and is required for IL-1 signal transduction. Interleukin 1 induces the synthesis of the acute phase and proinflammatory proteins during infection, tissue damage, or stress, by forming a complex at the cell membrane with an interleukin 1 receptor...
TMPY-05593 IL-1RAP/IL-1RAcP Protein, Human, Recombinant (His & Avi), Biotinylated

IL-1RAcP,interleukin 1 receptor accessory protein,C3orf13,IL...

Human HEK293
Interleukin-1 receptor accessory protein (IL-1RAcP) also known as Interleukin-1 receptor member 3 (IL-1R3) is a cytokine receptor that binds interleukin 1. The IL-1 receptor accessory protein (IL1RAP) is a transmembrane protein that interacts with IL-1R and is required for IL-1 signal transduction. Interleukin 1 induces the synthesis of the acute phase and proinflammatory proteins during infection, tissue damage, or stress, by forming a complex at the cell membrane with an interleukin 1 receptor...
TMPY-01250 IL-11R alpha/IL-11RA Protein, Mouse, Recombinant (His)

AI314697,Il11ra1,interleukin 11 receptor subunit alpha,NR1,I...

Mouse HEK293
Interleukin 11 receptor, alpha subunit (IL11RA/IL-11RA) is a subunit of the interleukin 11 receptor which is a member of the hematopoietic cytokine receptor family. IL11RA/IL-11RA is expressed in some cell lines, including the myelogenous leukemia cell line K562, the megakaryocytic leukemia cell line Mo7E, the erythroleukemia cell line TF1, and the osteosarcoma cell lines, MG-63 and Saos-2. It is also expressed in normal and malignant prostate epithelial cell lines. Expression levels are increas...
TMPY-01815 FOLR1 Protein, Human, Recombinant (His)

FBP,Folate Binding Protein,folate receptor 1 (adult),FOLR

Human HEK293
The protein encoded by FOLR1 gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transport 5-methyltetrahydrofolate into cells. This gene product is a secreted protein that either anchors to membranes via a glycosyl-phosphatidylinositol linkage or exists in a soluble form. Mutations in this gene have been associated with neurodegeneration due to cerebral folate transport deficiency. Due to the presence of two promoters, mul...
TMPJ-00042 TSLP Protein, Human, Recombinant

TSLP,Thymic stromal lymphopoietin

Human E. coli
Thymic stromal lymphopoietin (TSLP) is a novel member of the hemopoietic cytokine family that promotes the development of B cells and shares overlapping activity with IL-7. The human TSLP protein comprises a 28 amino acids (aa) signal sequence and 131 aa mature region. Human TSLP has two isoforms lfTSLP and sfTSLP produced by alternative splicing . lfTSLP is expressed in a number of tissues including heart, liver and prostate, and sfTSLP (63aa) is predominantly expressed in keratinocytes of oral...
TMPY-06022 FOLR1 Protein, Cynomolgus, Rhesus, Recombinant (His)

folate receptor 1 (adult)

Cynomolgus,Rhesus HEK293
The protein encoded by FOLR1 gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transport 5-methyltetrahydrofolate into cells. This gene product is a secreted protein that either anchors to membranes via a glycosyl-phosphatidylinositol linkage or exists in a soluble form. Mutations in this gene have been associated with neurodegeneration due to cerebral folate transport deficiency. Due to the presence of two promoters, mul...
TMPY-01882 HE4 Protein, Human, Recombinant (His)

dJ461P17.6,EDDM4,WAP four-disulfide core domain 2,WAP5,HE4

Human HEK293
WAP four-disulfide core domain protein 2, also known as Epididymal secretory protein E4, Major epididymis-specific protein E4, Putative protease inhibitor WAP5, WFDC2 and HE4, is a secreted protein that contains two WAP domains. WFDC2 / HE4 is a member of a family of stable 4-disulfide core proteins that are secreted at high levels. It is expressed in a number of normal tissues, including male reproductive system, regions of the respiratory tract and nasopharynx. It is highly expressed in a numb...
TMPY-01462 IL-11R alpha/IL-11RA Protein, Human, Recombinant (His)

interleukin 11 receptor subunit alpha,hCG_2011440,CRSDA,inte...

Human HEK293
Interleukin 11 receptor, alpha subunit (IL11RA/IL-11RA) is a subunit of the interleukin 11 receptor which is a member of the hematopoietic cytokine receptor family. IL11RA/IL-11RA is expressed in some cell lines, including the myelogenous leukemia cell line K562, the megakaryocytic leukemia cell line Mo7E, the erythroleukemia cell line TF1, and the osteosarcoma cell lines, MG-63 and Saos-2. It is also expressed in normal and malignant prostate epithelial cell lines. Expression levels are increas...
TMPY-02919 Cadherin 17/CDH17 Protein, Rat, Recombinant (His)

cadherin 17, LI cadherin (liver-intestine)

Rat HEK293
Cadherin-17 or LI-cadherin is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Cadherin-17/LI-cadherin is a cadherin-like protein consisting of an extracellular region, 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of ...
TMPY-05352 Cadherin 17/CDH17 Protein, Cynomolgus, Recombinant (hFc)

cadherin 17, LI cadherin (liver-intestine)

Cynomolgus HEK293
Cadherin-17 or LI-cadherin is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Cadherin-17/LI-cadherin is a cadherin-like protein consisting of an extracellular region, 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of ...
TMPY-01912 Cadherin 17/CDH17 Protein, Human, Recombinant (His)

HPT-1,cadherin 17, LI cadherin (liver-intestine),CDH16,HPT1

Human HEK293
Cadherin-17 or LI-cadherin is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Cadherin-17/LI-cadherin is a cadherin-like protein consisting of an extracellular region, 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of ...
TMPY-00803 Fibronectin Protein, Human, Recombinant (aa 607-1265, His)

GFND,LETS,ED-B,fibronectin 1,CIG,GFND2,FNZ,FINC,FN,MSF

Human HEK293
Fibronectin (FN) is a glycoprotein component of the extracellular matrix of the extracellular matrix (ECM) with roles in embryogenesis, development, and wound healing. More recently, FN has emerged as player in platelet thrombus formation and diseases associated with thrombosis including vascular remodeling, atherosclerosis, and cardiac repair following a myocardial infarct. Each monomer of FN consists of three types of homologous repeating units, that is 12 type I repeats, two type II repeats a...
TMPY-04902 Complement C5a Protein, Mouse, Recombinant

complement component 5

Mouse E. coli
C5a is a protein fragment released from complement component C5. This 74 amino acid peptide in humans is generated by the cleavage of C5a convertase on the C5 α-chain during the classical, alternative, and lectin pathways of complement activation. The structure of C5a includes a core region consisting of four, anti-parallel alpha-helices held together by three disulfide linkages and a structured C-terminal tail, and C5a is rapidly metabolised by carboxypeptidase B to a 73 amino acid low activity...
TMPY-00653 Complement C5 Protein, Human, Recombinant (Complement C5a)

C5D,C5b,CPAMD4,complement component 5,Complement C5,ECLZB,C5...

Human E. coli
C5a is a protein fragment released from complement component C5. This 74 amino acid peptide in humans is generated by the cleavage of C5a convertase on the C5 α-chain during the classical, alternative, and lectin pathways of complement activation. The structure of C5a includes a core region consisting of four, anti-parallel alpha-helices held together by three disulfide linkages and a structured C-terminal tail, and C5a is rapidly metabolised by carboxypeptidase B to a 73 amino acid low activity...
TMPY-05057 Complement C5 Protein, Human, Recombinant (His & FLAG)

C5b,ECLZB,C5a,CPAMD4,C5D,complement component 5,Complement C...

Human HEK293
C5a is a protein fragment released from complement component C5. This 74 amino acid peptide in humans is generated by the cleavage of C5a convertase on the C5 α-chain during the classical, alternative, and lectin pathways of complement activation. The structure of C5a includes a core region consisting of four, anti-parallel alpha-helices held together by three disulfide linkages and a structured C-terminal tail, and C5a is rapidly metabolised by carboxypeptidase B to a 73 amino acid low activity...
TMPH-02594 MMP-13 Protein, Mouse, Recombinant (His)

Mouse E. coli
Pre-mRNA alternative splicing regulator. Regulates alternative splicing of RBFOX2 to enhance the production of mRNA species that are targeted for nonsense-mediated decay (NMD).
TMPK-00151 Complement Factor D/CFD Protein, Mouse, Recombinant (hFc)

C3 convertase activator,AMBP-1,PFD,FACTOR D,CFD,ADN,EC 3.4.2...

Mouse HEK293
Complement factor D is a serine protease essential for the activation of the alternative pathway and is expressed in the kidney, adipocytes, and macrophages. Factor D is found at relatively high levels in glomeruli suggesting that this component of the complement cascade could influence renal pathophysiology.Complement factor D or alternative pathway activation is needed to prevent spontaneous accumulation of C3 and IgM deposits within the mesangium.
TMPK-00755 Complement Factor D/CFD Protein, Human, Recombinant (hFc)

C3 convertase activator,DF,AMBP-1,EC 3.4.21,EC 3.4.21.46,Adi...

Human HEK293
Complement factor D is a serine protease essential for the activation of the alternative pathway and is expressed in the kidney, adipocytes, and macrophages. Factor D is found at relatively high levels in glomeruli suggesting that this component of the complement cascade could influence renal pathophysiology.Complement factor D or alternative pathway activation is needed to prevent spontaneous accumulation of C3 and IgM deposits within the mesangium.
TMPY-03121 BPIFA2 Protein, Human, Recombinant (His)

SPLUNC2,bA49G10.1,BPI fold containing family A, member 2,PSP...

Human HEK293
C20orf70 belongs to the BPI/LBP/Plunc superfamily, Plunc family. PLUNC family is comprised by mucosal secretory proteins that are predicted to be structurally similar to lipid-binding and host-defense proteins including bactericidal/permeability-increasing protein and lipopolysaccharide-binding protein. C20orf70 can be detected in submandibular gland. C20orf70 gene contains 9 distinct gt-ag introns. Transcription produces 6 different mRNAs, 4 alternatively spliced variants and 2 unspliced forms....
TMPK-00671 Complement Factor D/CFD Protein, Rhesus macaque, Recombinant (His)

Adipsin,CFD,ADN,Complement factor D,DF,AMBP-1,EC 3.4.21,FACT...

Rhesus macaque HEK293
Complement factor D is a serine protease essential for the activation of the alternative pathway and is expressed in the kidney, adipocytes, and macrophages. Factor D is found at relatively high levels in glomeruli suggesting that this component of the complement cascade could influence renal pathophysiology.Complement factor D or alternative pathway activation is needed to prevent spontaneous accumulation of C3 and IgM deposits within the mesangium.
TMPY-03106 CCDC47 Protein, Human, Recombinant (His)

GK001,MSTP041,coiled-coil domain containing 47

Human HEK293
CCDC47 gene is expressed at high level. The gene contains 16 distinct gt-ag introns. Transcription produces 9 different mRNAs, 6 alternatively spliced variants and 3 unspliced forms. There are 3 probable alternative promotors, 3 non overlapping alternative last exons and 8 validated alternative polyadenylation sites. The mRNAs appear to differ by truncation of the 5' end, truncation of the 3' end, presence or absence of a cassette exon, overlapping exons with different boundaries. Functionally, ...
TMPH-00779 IL-23 P19/IL23A Protein, Guinea Pig, Recombinant (His & Myc)

Guinea pig E. coli
Does not have 2'-5'-OAS activity, but can bind double-stranded RNA. Displays antiviral activity against encephalomyocarditis virus (EMCV) and hepatitis C virus (HCV) via an alternative antiviral pathway independent of RNase L.
TMPH-02628 Cathepsin C Protein, Mouse, Recombinant (His & Myc)

Mouse E. coli
Acts as complement inhibitor by disrupting the formation of the classical C3 convertase. Isoform 3 inhibits the classical complement pathway, while membrane-bound isoform 1 inhibits deposition of C3b via both the classical and alternative complement pathways.
TMPY-04694 CCDC47 Protein, Mouse, Recombinant (His)

calumin,asp4,coiled-coil domain containing 47,2610204L23Rik,...

Mouse HEK293
CCDC47 gene is expressed at high level. The gene contains 16 distinct gt-ag introns. Transcription produces 9 different mRNAs, 6 alternatively spliced variants and 3 unspliced forms. There are 3 probable alternative promotors, 3 non overlapping alternative last exons and 8 validated alternative polyadenylation sites. The mRNAs appear to differ by truncation of the 5' end, truncation of the 3' end, presence or absence of a cassette exon, overlapping exons with different boundaries. Functionally, ...
TMPY-02966 BPIFA2 Protein, Human, Recombinant (hFc)

bA49G10.1,BPI fold containing family A, member 2,PSP,C20orf7...

Human HEK293
C20orf70 belongs to the BPI/LBP/Plunc superfamily, Plunc family. PLUNC family is comprised by mucosal secretory proteins that are predicted to be structurally similar to lipid-binding and host-defense proteins including bactericidal/permeability-increasing protein and lipopolysaccharide-binding protein. C20orf70 can be detected in submandibular gland. C20orf70 gene contains 9 distinct gt-ag introns. Transcription produces 6 different mRNAs, 4 alternatively spliced variants and 2 unspliced forms....
TMPK-01075 CD163 Protein, Human, Recombinant (His & Avi), Biotinylated

HbSR,sCD163,M130,GHI/61,MM130,CD163 molecule,CD163,RM3/1,SCA...

Human HEK293
The hemoglobin (Hb) scavenger receptor, CD163, is a macrophage-specific protein and the upregulated expression of this receptor is one of the major changes in the macrophage switch to alternative activated phenotypes in inflammation. Accordingly, a high CD163 expression in macrophages is a characteristic of tissues responding to inflammation.
TMPK-00550 CD55/DAF Protein, Cynomolgus, Recombinant (His)

TC,DAF-GPI,CR,CROM,Daf1,CD55,Cd55a,DAF

Cynomolgus HEK293
Decay Accelerating Factor (or CD55) is a major regulator of the alternative and classical pathways of complement activation and is expressed on all serum-exposed cells. It is commonly hijacked by invading pathogens, including many enteroviruses and uropathogenic Escherichia coli, to promote cellular attachment prior to infection.
TMPY-02288 Glyoxalase II/HAGH Protein, Human, Recombinant (His)

HAGH1,GLO2,GLX2,hydroxyacylglutathione hydrolase,GLXII

Human E. coli
HAGH (Hydroxyacylglutathione Hydrolase) is a Protein Coding gene. 3 alternative splicing and alternative initiation of human isoforms have been reported. The enzyme encoded by this gene is classified as a thioesterase and is responsible for the hydrolysis of S-lactoyl-glutathione to reduced glutathione and D-lactate. HAGH belongs to the Metallo-beta-lactamase superfamily. HAGH is widely expressed in the kidney, liver, and other tissues. Diseases associated with HAGH include Hydroxyacyl Glutathio...
TMPK-00983 CD163 Protein, Mouse, Recombinant (His)

GHI/61,CD163 molecule,sCD163,HbSR,MM130,SCARI1,M130,CD163,RM...

Mouse HEK293
The hemoglobin (Hb) scavenger receptor, CD163, is a macrophage-specific protein and the upregulated expression of this receptor is one of the major changes in the macrophage switch to alternative activated phenotypes in inflammation. Accordingly, a high CD163 expression in macrophages is a characteristic of tissues responding to inflammation.
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重组蛋白

CD163 Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-01074
Species: Human
Expression System: HEK293
HER3/ERBB3 Protein, Human, Recombinant
Cat.No: TMPY-00399
Species: Human
Expression System: HEK293
HER3/ERBB3 Protein, Human, Recombinant (His)
Cat.No: TMPY-01389
Species: Human
Expression System: HEK293
HER3/ERBB3 Protein, Rhesus, Recombinant
Cat.No: TMPY-00246
Species: Rhesus
Expression System: HEK293
IL-15RA Protein, Mouse, Recombinant (hFc)(Human Cells)
Cat.No: TMPJ-00154
Species: Mouse
Expression System: Human Cells
ENTPD2 Protein, Human, Recombinant (aa 29-460, His)
Cat.No: TMPY-02929
Species: Human
Expression System: Baculovirus-Insect Cells
HER3/ERBB3 Protein, Rat, Recombinant (His)
Cat.No: TMPY-03024
Species: Rat
Expression System: HEK293
HER3/ERBB3 Protein, Rhesus, Recombinant (His)
Cat.No: TMPY-02477
Species: Rhesus
Expression System: HEK293
HER3/ERBB3 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-02365
Species: Mouse
Expression System: HEK293
HER3/ERBB3 Protein, Human, Recombinant (His), Biotinylated
Cat.No: TMPY-04956
Species: Human
Expression System: HEK293
CD16a Protein, Cynomolgus, Recombinant (His), Biotinylated
Cat.No: TMPY-05538
Species: Cynomolgus
Expression System: HEK293
CD16a Protein, Human, Recombinant (F176V, His)
Cat.No: TMPY-01964
Species: Human
Expression System: HEK293
CD16a Protein, Rat, Recombinant (His)
Cat.No: TMPY-02018
Species: Rat
Expression System: HEK293
TIGIT Protein, Cynomolgus, Recombinant (hFc)
Cat.No: TMPY-05345
Species: Cynomolgus
Expression System: HEK293
CRLF2/TSLPR Protein, Human, Recombinant (His)
Cat.No: TMPY-05242
Species: Human
Expression System: HEK293
VCAM-1 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01830
Species: Mouse
Expression System: HEK293
TIGIT Protein, Human, Recombinant (hFc)
Cat.No: TMPY-04970
Species: Human
Expression System: HEK293
TIGIT Protein, Mouse, Recombinant (His)
Cat.No: TMPY-02669
Species: Mouse
Expression System: HEK293
VCAM-1 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00947
Species: Human
Expression System: HEK293
FOLR1 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01803
Species: Mouse
Expression System: HEK293
IL-1RAP/IL-1RAcP Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPY-05840
Species: Cynomolgus
Expression System: HEK293
IL-1RAP/IL-1RAcP Protein, Mouse, Recombinant (His)
Cat.No: TMPY-04580
Species: Mouse
Expression System: HEK293
IL-1RAP/IL-1RAcP Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-05593
Species: Human
Expression System: HEK293
IL-11R alpha/IL-11RA Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01250
Species: Mouse
Expression System: HEK293
FOLR1 Protein, Human, Recombinant (His)
Cat.No: TMPY-01815
Species: Human
Expression System: HEK293
TSLP Protein, Human, Recombinant
Cat.No: TMPJ-00042
Species: Human
Expression System: E. coli
FOLR1 Protein, Cynomolgus, Rhesus, Recombinant (His)
Cat.No: TMPY-06022
Species: Cynomolgus,Rhesus
Expression System: HEK293
HE4 Protein, Human, Recombinant (His)
Cat.No: TMPY-01882
Species: Human
Expression System: HEK293
IL-11R alpha/IL-11RA Protein, Human, Recombinant (His)
Cat.No: TMPY-01462
Species: Human
Expression System: HEK293
Cadherin 17/CDH17 Protein, Rat, Recombinant (His)
Cat.No: TMPY-02919
Species: Rat
Expression System: HEK293
Cadherin 17/CDH17 Protein, Cynomolgus, Recombinant (hFc)
Cat.No: TMPY-05352
Species: Cynomolgus
Expression System: HEK293
Cadherin 17/CDH17 Protein, Human, Recombinant (His)
Cat.No: TMPY-01912
Species: Human
Expression System: HEK293
Fibronectin Protein, Human, Recombinant (aa 607-1265, His)
Cat.No: TMPY-00803
Species: Human
Expression System: HEK293
Complement C5a Protein, Mouse, Recombinant
Cat.No: TMPY-04902
Species: Mouse
Expression System: E. coli
Complement C5 Protein, Human, Recombinant (Complement C5a)
Cat.No: TMPY-00653
Species: Human
Expression System: E. coli
Complement C5 Protein, Human, Recombinant (His & FLAG)
Cat.No: TMPY-05057
Species: Human
Expression System: HEK293
MMP-13 Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02594
Species: Mouse
Expression System: E. coli
Complement Factor D/CFD Protein, Mouse, Recombinant (hFc)
Cat.No: TMPK-00151
Species: Mouse
Expression System: HEK293
Complement Factor D/CFD Protein, Human, Recombinant (hFc)
Cat.No: TMPK-00755
Species: Human
Expression System: HEK293
BPIFA2 Protein, Human, Recombinant (His)
Cat.No: TMPY-03121
Species: Human
Expression System: HEK293
Complement Factor D/CFD Protein, Rhesus macaque, Recombinant (His)
Cat.No: TMPK-00671
Species: Rhesus macaque
Expression System: HEK293
CCDC47 Protein, Human, Recombinant (His)
Cat.No: TMPY-03106
Species: Human
Expression System: HEK293
IL-23 P19/IL23A Protein, Guinea Pig, Recombinant (His & Myc)
Cat.No: TMPH-00779
Species: Guinea pig
Expression System: E. coli
Cathepsin C Protein, Mouse, Recombinant (His & Myc)
Cat.No: TMPH-02628
Species: Mouse
Expression System: E. coli
CCDC47 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-04694
Species: Mouse
Expression System: HEK293
BPIFA2 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-02966
Species: Human
Expression System: HEK293
CD163 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-01075
Species: Human
Expression System: HEK293
CD55/DAF Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-00550
Species: Cynomolgus
Expression System: HEK293
Glyoxalase II/HAGH Protein, Human, Recombinant (His)
Cat.No: TMPY-02288
Species: Human
Expression System: E. coli
CD163 Protein, Mouse, Recombinant (His)
Cat.No: TMPK-00983
Species: Mouse
Expression System: HEK293
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