unc4976

UNC4976 is a peptidomimetic positive allosteric modulator (PAM) of the CBX7 chromodomain, facilitating its binding to nucleic acids.

UNC4976 TFA为CBX7染色质结构域与核酸结合的PAM（正变构调节剂）拟肽。通过拮抗H3K27me3，特异性阻断CBX7对靶基因的募集，同时促进了与DNA和RNA的非特异性结合。