Pro-neuregulin-1,Neuregulin-1 beta 1(NRG1) is a single-pass type I membrane protein and belongs to the neuregulin family .It contains 1 EGF-like domain and 1 Ig-like C2-type (immunoglobulin-like) domain. Direct ligand for ERBB3 and ERBB4 tyrosine kinase receptors. The protein concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. The multiple isoforms perform diverse functions such as inducing growth and differentiation of epithelial, glial, neuronal, and skeletal muscle cells; inducing expression of acetylcholine receptor in synaptic vesicles during the formation of the neuromuscular junction; stimulating lobuloalveolar budding and milk production in the mammary gland and inducing differentiation of mammary tumor cells; stimulating Schwann cell proliferation; implication in the development of the myocardium such as trabeculation of the developing heart. Isoform 10 may play a role in motor and sensory neuron development.
Neuregulin-1 NRG1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 35.5 kDa and the accession number is Q02297-12.
NRG1 beta 1 Protein, Human, Recombinant (EGF Domain, hFc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 36.7 kDa and the accession number is Q02297-6.
Neuregulin-1 NRG1 Protein, Canine, Recombinant (aa 19-240, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.5 kDa and the accession number is XP_858147.1.
Neuregulin-1 NRG1 Protein, Canine, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 24.7 kDa and the accession number is XP_858147.1.
Neuregulin-1 NRG1 Protein, Canine, Recombinant (aa 176-240, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 9.7 kDa.
NRG1 alpha Protein, Human, Recombinant (EGF Domain, hFc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 35.8 kDa and the accession number is Q02297-1.
NRG1 alpha Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 51 kDa and the accession number is Q02297-1.
NRG1 beta 1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 55.2 kDa and the accession number is Q02297-6.
Neuregulin-1 NRG1 Protein, Canine, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 34 kDa and the accession number is XP_858147.1.
NRG1 beta 1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 26.8 kDa and the accession number is Q02297-6.
Neuregulin-1 NRG1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.3 kDa and the accession number is Q02297-12.
Neuregulin-1 NRG1 Protein, Canine, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 50.8 kDa and the accession number is XP_858147.1.
NRG1 alpha Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.5kDa and the accession number is Q02297-1.
CLEC2B Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 42.9 kDa and the accession number is AAH05254.1.