nrg 1

Pro-neuregulin-1,Neuregulin-1 beta 1(NRG1) is a single-pass type I membrane protein and belongs to the neuregulin family .It contains 1 EGF-like domain and 1 Ig-like C2-type (immunoglobulin-like) domain. Direct ligand for ERBB3 and ERBB4 tyrosine kinase receptors. The protein concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. The multiple isoforms perform diverse functions such as inducing growth and differentiation of epithelial, glial, neuronal, and skeletal muscle cells; inducing expression of acetylcholine receptor in synaptic vesicles during the formation of the neuromuscular junction; stimulating lobuloalveolar budding and milk production in the mammary gland and inducing differentiation of mammary tumor cells; stimulating Schwann cell proliferation; implication in the development of the myocardium such as trabeculation of the developing heart. Isoform 10 may play a role in motor and sensory neuron development.

NRG1 beta 1 Protein, Human, Recombinant (CHO) is expressed in CHO Cells. The accession number is Q02297-6.

Expression system: HEK293 Cells
Length: 20-238, Partial
Activity: Not Tested

Expression system: HEK293 Cells
Length: 177-237, Partial
Activity: Not Tested

Expression system: HEK293 Cells
Length: 176-246, Partial
Activity: ELISA

Expression system: HEK293 Cells
Length: 2-246, Partial
Activity: ELISA

Expression system: HEK293 Cells
Length: 177-241, Partial
Activity: ELISA

Expression system: HEK293 Cells
Length: 20-241, Partial
Activity: ELISA

Expression system: HEK293 Cells
Length: 20-241, Partial
Activity: ELISA

Expression system: HEK293 Cells
Length: 2-246, Partial
Activity: Cells Activity

Neuregulin-1 NRG1 Protein, Canine, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 34 kDa and the accession number is XP_858147.1.

Neuregulin-1 NRG1 Protein, Canine, Recombinant (aa 19-240, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.5 kDa and the accession number is XP_858147.1.

Neuregulin-1 NRG1 Protein, Canine, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 50.8 kDa and the accession number is XP_858147.1.

Neuregulin-1 NRG1 Protein, Canine, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 24.7 kDa and the accession number is XP_858147.1.

Neuregulin-1 NRG1 Protein, Canine, Recombinant (aa 176-240, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 9.7 kDa.

Expression system: HEK293 Cells
Length: 2-246, Partial of Isoform 6
Activity: Not Tested

Expression system: E. coli
Length: 176-246, Partial
Activity: Cells Activity

Expression system: E. coli
Length: 75-176, Partial
Activity: Not Tested

CLEC2B Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 42.9 kDa and the accession number is AAH05254.1.