enniatin a

Enniatin A is a Fusarium mycotoxin. Enniatin A inhibits acyl-CoA: cholesterol acyltransferase (ACAT) activity with an IC50 of 22 μM in an enzyme assay using rat liver microsomes.

Enniatin F 是一种天然化合物，可作为天然产物对照品，其 CAS 号为 144446-20-8。

Enniatin A1 possesses anticarcinogenic properties by induction of apoptosis and disruption of ERK signalling pathway. Enniatin A1 inhibits ACAT with an IC50 of 49 μM in rat liver microsomes. Enniatin A1 isolated from Fusarium mycotoxins is a cyclic hexadepsipeptide consisting of alternating D-α-hydroxyisovaleric acids and N-methyl-L-amino acids.

Enniatin C 是一种具有膜活性的抗生素，具有抗疟活性，抑制结核分枝杆菌，可用于研究真菌感染。

Enniatin complex, a mixture of cyclohexadepsipeptides predominantly derived from various Fusarium species of fungi, exhibits inhibitory effects on enzymes such as acyl-CoA: cholesterol acyl transferase. Furthermore, it has demonstrated the ability to induce apoptosis in multiple cancer cell lines. In addition to these activities, the Enniatin complex possesses ionophoric, antibiotic, and in vitro hypolipidemic properties.

Enniatins B decreases the activation of ERK (p44 p42). Enniatin B is a Fusarium mycotoxin. Enniatin B inhibits acyl-CoA: cholesterol acyltransferase (ACAT) activity with an IC50 of 113 μM in an enzyme assay using rat liver microsomes.

Enniatin B1 crosss the blood-brain barrier. Enniatin B1 decreases the activation of ERK (p44 p42). Enniatin B1 inhibits moderately TNF-α-induced NF-κB activation.Enniatin B1 is a Fusarium mycotoxin. Enniatin B1 inhibits acyl-CoA: cholesterol acyltransferase (ACAT) activity with an IC50 of 73 μM in an enzyme assay using rat liver microsomes.

Aurofusarin由禾谷镰刀菌这种广泛感染温带气候区域重要作物的病原真菌产生，属于次生代谢产物。此外，禾谷镰刀菌还能制造其他化合物，包括单形甘露醇、镰刀菌素 C、抗生素 Y、2-氨基-14,16-二甲基十八烷-3-醇（2-AOD-3-ol）、气囊孢醇及恩尼亚菌素。