chromogenic

H-D-Phe-Pip-Arg-pNA dihydrochloride (S-2238 dihydrochloride )是一种显色底物，模仿了纤维蛋白原Aα链N端片段，即凝血酶的天然底物。H-D-Phe-Pip-Arg-pNA dihydrochloride 专为凝血酶检测而设计，用于抗凝血酶-肝素辅因子(AT-III)的定量。利用该底物的AT-III检测方法以其灵敏度、准确性和实施的便捷性而特别闻名。

4-Methylumbelliferyl-β-D-Glucopyranoside (4-MU-GLU) 是β-glucosidase 的荧光底物，可用于β-glucosidase 活性的测定，期间释放出高荧光的 4-methylumbelliferyl (4-MU)，发射波长为 445-454 nm。4-MU 激发波长值与 pH 值有关，在 pH 值为 4.6、7.4 和 10.4 时分别为 330、370 和 385 nm。

GLcNAc1-b-PNP 是N-乙酰基-β-氨基葡萄糖酶的发色底物，可用于量化人血清和尿液中N-乙酰基-β-D-氨基葡萄糖酶的活性。

2-Amino-3-hydroxypyridine 作为显色试剂用于分光光度法测定锇。

6-Chloro-3-indolyl-β-D-Glucuronide (cyclohexylammonium salt) 是 β-glucuronidase 的显色底物。 6-Chloro-3-indolyl-β-D-Glucuronide (cyclohexylammonium salt) 可用于组织化学分析 β-glucuronidase 活性。

ERAP1-in-1 是一种内质网氨基肽酶 1 (ERAP1) 抑制剂，能竞争性地抑制 ERAP1 对代表性生物底物九聚物肽的作用。

Ac-EVKKQR-pNA是一种针对NS2B-NS3切割位点P6-P1段的竞争性对硝基苯胺底物，该底物在P1位置采用了更易反应的可水解偏硝基苯胺。此化合物对于研究登革热2型病毒和黄病毒感染具有重要的应用潜力。

X-NeuNAc (5-Bromo-4-chloro-3-indolyl-alpha-D-N-acetylneuraminic acid sodium salt) 是细菌表达系统中神经氨酸酶活性的一种新的显色测定底物。

Phe-Pro-Arg-PABA-Resorufin is a Chromogenic and fluorogenic peptide substrate for the highly sensitive detection of proteases in biological matrices. The substrate is also applicable to the sensitive detection of the thrombin inhibitor dabigatran in human

Chromozym PK is a chromogenic substrate for factor XII assay.

Chromozym U can be used as a chromogenic substrate test for urokinase in Shigella.

S 2160 is a synthetic chromogenic substrate for thrombin.

S 2238 is a chromogenic substrate for thrombin that is used in amidolytic assay.

S 2423 is a chromogenic substrate.

S 2366 is a chromogenic substrate for Factor XI in plasma.

Bz-IEGR-pNA is a colorimetric substrate for Factor Xa.1 Factor Xa preferentially binds to and cleaves the Ile-Glu-Gly-Arg (IEGR) peptide sequence to release p-nitroanilide (pNA), which can be quantified by colorimetric detection at 405 nm as a measure of Factor Xa activity.References1. Aruell, L., Friberger, P., Karlsson, G., et al. A new sensitive and highly specific chromogenic peptide substrate for factor Xa. Thromb. Res. 11(5), 595-609 (1977). Bz-IEGR-pNA is a colorimetric substrate for Factor Xa.1 Factor Xa preferentially binds to and cleaves the Ile-Glu-Gly-Arg (IEGR) peptide sequence to release p-nitroanilide (pNA), which can be quantified by colorimetric detection at 405 nm as a measure of Factor Xa activity. References1. Aruell, L., Friberger, P., Karlsson, G., et al. A new sensitive and highly specific chromogenic peptide substrate for factor Xa. Thromb. Res. 11(5), 595-609 (1977).

Suc-YVAD-pNA, a chromogenic caspase-1 substrate.

pFR-pNA, chromogenic substrate for the determination of plasma kallikrein-like activity. CAS Number (net): 64816-19-9.

Z-RGR-pNA is a chromogenic substrate for the determination of factor Xa.

Diheptanoyl Thio-PC is a substrate for all phospholipase A2s (PLA2s) with the exception of cPLA2 and PAF-acetyl hydrolase (PAF-AH). Interaction of this compound with a PLA2 results in cleavage of the sn-2 fatty acid generating a free thiol on the lysophospholipid. This free thiol can be detected using chromogenic substrates such as DTNB (Ellman's reagent) and DTP.

Thioester analogs of glycerophospholipids, in combination with Ellman's reagent, are convenient colorimetric substrates for the measurement of phospholipase (PL) activity. Palmitoyl thio-PC is a chromogenic PLA2 substrate that contains a palmitoyl thioester at the sn-2 position of the glycerol backbone. Hydrolysis of the thioester by PLA2 yields a free thiol that reacts readily with DTNB (Ellman's reagent) giving a bright yellow product with an absorbance maximum at 412 nm. Palmitoyl thio-PC has been used to measure bee venom sPLA2 activity in a phospholipid:Triton X-100 mixed micelle system.

p-Nitrophenylphosphorylcholine is a chromogenic substrate that is used to measure phospholipase C (PLC) activity. Hydrolysis of p-nitrophenylphosphorylcholine by PLC results in the liberation of p-nitrophenol, which can be measured at 405 nm at pH 7.2-7.5.

4-Nitrophenyl β-D-cellotrioside is a chromogenic substrate for endoglucanases and cellobiohydrolases. Hydrolysis of this substrate by these enzymes liberates 4-nitrophenol, which generates a yellow color that is measured by monitoring absorbance at 405 nm.

N-acetyl-D-galactosaminidase catalyzes the cleavage of N-acetylglucosamine (GlcNAc), the monomeric unit of the polymer chitin. 4-Nitrophenyl-N-acetyl-α-D-galactosaminide can be used as a chromogenic substrate for N-acetyl-D-galactosaminidase, generating a yellow solution upon cleavage.