charybdotoxin

Specific inhibitor of the big conductance Ca2+-activated K+ channel.

Charybdotoxin TFA 是一种含 37 个氨基酸的肽，是一个K+通道阻滞剂。

ChTX-Lq2为Ca2+激活的K+流出抑制剂，Kd值为43 nM。

Paspalinine can inhibit binding of [125I]charybdotoxin (ChTX) to maxi-K channels in bovine aortic smooth muscle sarcolemmal membranes. Paspalinine shows tremorgenic action, which may be due in part to their inhibition of GABAA receptor function.