Olezarsen sodium, an N-acetyl-galactosamine-conjugated antisense oligonucleotide, targets hepatic APOC3 mRNA to suppress the production of apolipoprotein C-III (apoC-III). This action helps reduce triglyceride levels in patients at high risk for or with established cardiovascular disease.
Olezarsen, an N-acetyl-galactosamine-conjugated antisense oligonucleotide, targets hepatic APOC3 mRNA to inhibit the production of apolipoprotein C-III (apoC-III), thereby lowering triglyceride levels in patients who are at high risk for or have established cardiovascular disease.