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Search Results for " md2 "

Targets Recommended: TLR

抑制剂 & 化合物

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T4231	MD2-IN-1	TLR	Immunology/Inflammation
	MD2-IN-1 是骨髓分化蛋白 2 (MD2) 的抑制剂，对重组人 MD2 (rhMD2) 的 KD 为 189 μM。
T7672	MD2-TLR4-IN-1	TLR	Immunology/Inflammation
	MD2-TLR4-IN-1 是一种骨髓分化蛋白 2/toll 样受体 4 (MD2-TLR4) 复合物抑制剂，能够抑制巨噬细胞 LPS 诱导的 TNF-α 和 IL-6 的表达，IC50值分别为 0.89 和 0.53 μM。
T40423	L48H37
	L48H37是Curcumin的一个化学稳定类似物。它对髓系分化蛋白2 (MD2) 表现出强效的抑制性质，作为一个特异性抑制剂。其机制包括抑制LPS-TLR4/MD2的相互作用和信号传导。L48H37主要用于脓血症和肺损伤研究[1]。
T25503	Hisphen Synonyms Hisfen,MD 2
	Hisphen shows antileukemic activity.
T5399	GeA-69	PARP	Chromatin/Epigenetic; DNA Damage/DNA Repair
	GeA-69 是一种选择性变构 PARP14 大结构域 2 (MD2) 抑制剂，Kd 值为 2.1 µM。
T70932	L6H9
	L6H9 is a novel inhibitor of myeloid differentiation factor 2 (MD2), suppressing HG-induced expression of ACE and AT1 receptor and Angiotensin II (AngII) production in renal NRK‐52E cells, resulting in the decrease in fibrosis markers such as TGF-β and collagen IV.
T80154	TAT-CIRP
	TAT-CIRP为小肽，指Tat融合的冷诱导RNA结合蛋白。作为骨髓分化蛋白2（MD2）的抑制剂，该化合物对小鼠缺血性及出血性中风显示出显著的神经保护效果。

化合物

Synonym: Synonyms Hisfen,MD 2

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-03999	MD2/LY96 Protein, Mouse, Recombinant (hFc) lymphocyte antigen 96,ESOP-1,MD2,MD	Mouse	HEK293 Cells
	LY96 (Lymphocyte Antigen 96, also known as ESOP-1) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. This gene encodes a protein that associates with toll-like receptor 4 on the cell surface and confers responsiveness to lipopolysaccharide (LPS), thus providing a link between the receptor and LPS signaling. LY-96 also cooperates with TLR2 in the response to cell wall components from Gram-positive and Gram-negative bacteria. It enhances the TLR4-dependent activa...
TMPK-00632	MD2/LY96 Protein, Cynomolgus, Recombinant (His) ESOP-1,LY96,Lymphocyte antigen 96,ESOP1,MD-2	Cynomolgus	E. coli
	MD2, a 160-residue accessory glycoprotein, is responsible for the recognition and binding of Gram-negative bacterial membrane component, lipopolysaccharide (LPS).Internalization of pathogen inside the mononuclear phagocytes has also been attributed to MD2 which leads to the clearance of pathogens from the host. MD2/LY96 Protein, Cynomolgus, Recombinant (His) is expressed in E. coli expression system with C-His tag. The predicted molecular weight is 17.97 kDa and the accession number is B3Y6B0.
TMPK-01242	MD2/LY96 Protein, Human, Recombinant (His) MD-2,Ly-96,ESOP-1,Lymphocyte antigen 96,LY...	Human	E. coli
	MD2, a 160-residue accessory glycoprotein, is responsible for the recognition and binding of Gram-negative bacterial membrane component, lipopolysaccharide (LPS).Internalization of pathogen inside the mononuclear phagocytes has also been attributed to MD2 which leads to the clearance of pathogens from the host. MD2/LY96 Protein, Human, Recombinant (His) is expressed in E. coli expression system with C-His tag. The predicted molecular weight is 18.07 kDa and the accession number is Q9Y6Y9-1.