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Targets Recommended: Others Drug-Linker Conjugates for ADC

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Cat. No. Product Name Target Signaling Pathways
T16024 MC-GGFG-DX8951

Others; Drug-Linker Conjugates for ADC Antibody-drug Conjugate/ADC Related; Others
MC-GGFG-DX8951 is a drug-linker conjugate designed for antibody-drug conjugation (ADC) that demonstrates antitumor activity through the deployment of DX8951, a DNA topoisomerase I inhibitor, connected using the protease-cleavable MC-GGFG linker[1].
T77847 MC-Val-Cit-PAB-Exatecan

MC-Val-Cit-PAB-DX8951

Others; Drug-Linker Conjugates for ADC Antibody-drug Conjugate/ADC Related; Others
MC-Val-Cit-PAB-Exatecan (MC-Val-Cit-PAB-DX8951) 是一种抗体-活性分子偶联物(ADC)的关键部分,由 DNA 拓扑异构酶 I 抑制剂 DX-8951 和组织蛋白酶敏感的连接子共同构成。
T75117 Py-MAA-Val-Cit-PAB-DX8951

Others Others
Py-MAA-Val-Cit-PAB-DX8951 是一种参与合成抗体药物偶联物(ADCs)中间体的嘌呤毒素。
T11249 Exatecan

依喜替康,DX-8951,DX-8951f

Topoisomerase; ADC Cytotoxin Antibody-drug Conjugate/ADC Related; DNA Damage/DNA Repair
Exatecan (DX-8951f) 是一种 DNA 拓扑异构酶 I (TOP1) 抑制剂,IC50 值为 2.2 μM (0.975 μg/mL)。Exatecan 具有抗肿瘤活性,可用于癌症研究。

化合物

MC-GGFG-DX8951
Cat.No: T16024
Synonym:
Target: Others, Drug-Linker Conjugates for ADC
MC-Val-Cit-PAB-Exatecan
Cat.No: T77847
Synonym: MC-Val-Cit-PAB-DX8951
Target: Others, Drug-Linker Conjugates for ADC
Py-MAA-Val-Cit-PAB-DX8951
Cat.No: T75117
Synonym:
Target: Others
Exatecan
Cat.No: T11249
Synonym: 依喜替康,DX-8951,DX-8951f
Target: Topoisomerase, ADC Cytotoxin
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