Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T2881 |
Crustecdysone
20-Hydroxyecdysone; Ecdysterone; B-ecdysone; Commisterone; B-ecdysone,Commisterone; β-蜕皮甾酮; 羟基蜕皮激素; Hydroxyecdysone |
Others; Caspase; Endogenous Metabolite; Autophagy | Apoptosis; Autophagy; Metabolism; Others; Proteases/Proteasome |
Crustecdysone 是来源于露水草的一种蜕皮激素,可调节昆虫的蜕皮或蜕皮过程。它是 Ecdysone的活性代谢物,通过 20E 核受体复合物 EcR-USP 抑制半胱天冬酶活性并诱导自噬,在心血管系统中具有调节或保护作用。 | |||
TN3910 | Ecdysone | Potassium Channel; Glucocorticoid Receptor; ATPase; Apoptosis; Sodium Channel; Endogenous Metabolite; Autophagy | Apoptosis; Autophagy; Endocrinology/Hormones; Membrane transporter/Ion channel; Metabolism |
Ecdysone 是存在于昆虫和草药中的主要类固醇激素,可以激活盐皮质激素受体并诱导细胞凋亡。Ecdysone 的活性代谢物 20-羟基蜕皮激素在协调发育过渡和体内稳态睡眠调节中起重要作用。 |