|
L1710
|
抗COVID-19化合物库
|
|
1160 compounds
|
|
1160种对SARS-CoV-2有抑制作用或潜在抑制作用的化合物集合，可用于高通量和高内涵筛选；
|
|
L6720
|
抗COVID-19中药单体库
|
|
1162 compounds
|
|
根据抗新冠肺炎疫情过程中应用于临床治疗的中药方剂，收集了1162种相关中药来源的单体化合物，可用于高通量和高内涵筛选，是抗新冠病毒药物研发的良好工具；
|
|
NY1000
|
天然产物衍生物库
|
|
4000 compounds
|
|
22个天然产物骨架，4000个天然产物衍生物；
|
|
L4900
|
心血管毒性化合物库
|
|
127 compounds
|
|
127种心血管毒性化合物的独特集合，可用于毒理学研究；
|
|
L2520
|
糖代谢化合物库
|
|
708 compounds
|
|
708种糖代谢相关的化合物，可用于高通量和高内涵筛选；
|
|
L9411
|
半胱氨酸共价化合物库
|
|
72 compounds
|
|
半胱氨酸共价库包含72个化合物。
|
|
L9230
|
ReFRAME 化合物库
|
|
3274 compounds
|
|
3274化合物的独特集合，可用于高通量筛选和高内涵筛选
|
|
DC1140
|
特权片段注释化合物库-Ligand-gated
|
|
9028 compounds
|
|
|
|
DC1180
|
特权片段注释化合物库-Lyases
|
|
19530 compounds
|
|
|
|
DC1150
|
特权片段注释化合物库-GPCR Family B
|
|
9320 compounds
|
|
|
|
DC1170
|
特权片段注释化合物库-Oxidoreductases
|
|
8812 compounds
|
|
|
|
DC1190
|
特权片段注释化合物库-Sigma Opioid receptors
|
|
8724 compounds
|
|
|
|
DC1040
|
特权片段注释化合物库-Transferases
|
|
23001 compounds
|
|
|
|
DC1030
|
特权片段注释化合物库-Epigenetics
|
|
9196 compounds
|
|
|
|
DC1100
|
特权片段注释化合物库-GPCR Frizzled family
|
|
3434 compounds
|
|
|
|
DC1200
|
特权片段注释化合物库-Isomerases
|
|
1206 compounds
|
|
|
|
DC1050
|
特权片段注释化合物库-Voltage-gated
|
|
17952 compounds
|
|
|
|
DC1110
|
特权片段注释化合物库-Proteases
|
|
22863 compounds
|
|
|
|
DC1010
|
特权片段注释化合物库-GPCR Family A
|
|
24763 compounds
|
|
|
|
DC1000
|
特权片段注释化合物库
|
|
190000 compounds
|
|
The database contains 190k small molecules divided into 23 sub libraries each focused at a specific target.
According to the recent studies, molecules acting on a particular target or class of targets usually have characteristic moieties (PF) containing key binding points responsible for activity, e.g. hinge-binding fragments. We used this principle for the statistical analysis of the reported active molecules and corresponding targets for the annotation of pre-filtered ChemDiv in house colle...
|
|
DC1130
|
特权片段注释化合物库-Phosphodiesterases
|
|
13154 compounds
|
|
|
|
DC1060
|
特权片段注释化合物库-Kinases
|
|
18350 compounds
|
|
|
|
DC1220
|
特权片段注释化合物库-Aminoacyltransferases
|
|
3008 compounds
|
|
|
|
DC1210
|
特权片段注释化合物库-Phosphatases
|
|
15354 compounds
|
|
|
|
DC1160
|
特权片段注释化合物库-Toll-like and Il-1 receptors
|
|
3536 compounds
|
|
|
|
DC1090
|
特权片段注释化合物库-Ligases
|
|
11828 compounds
|
|
|
|
DQ3000
|
Factor XIa化合物库
|
|
6500 compounds
|
|
|
|
DC1080
|
特权片段注释化合物库-GPCR Taste family
|
|
2675 compounds
|
|
|
|
DC1120
|
特权片段注释化合物库-Thrombopoietin receptors
|
|
4908 compounds
|
|
|
|
DC1230
|
特权片段注释化合物库-Beta amyloid A4 protein
|
|
4617 compounds
|
|
|
|
DC1070
|
特权片段注释化合物库-GPCR Family C
|
|
5071 compounds
|
|
|
|
DC1020
|
特权片段注释化合物库-Spiro Library
|
|
20563 compounds
|
|
|
|
L3980
|
DNA损伤/修复库Plus
|
|
667 compounds
|
|
667种DNA损伤/修复靶向、结构新颖的化合物；
|
|
L4700
|
免疫/炎症分子化合物库
|
|
3483 compounds
|
|
3483种具有抗炎症活性的化合物的特有集合，可用于高通量筛选和高内涵筛选；
|
|
L2200
|
酪氨酸激酶分子库
|
|
746 compounds
|
|
746种酪氨酸激酶抑制剂的独特集合，可用于高通量筛选和高内涵筛选；
|
|
L5100
|
含氟化合物库
|
|
583 compounds
|
|
583个含氟化合物的独特集合，可用于高通量筛选和高内涵筛选；
|
|
L4400
|
抗生素库
|
|
708 compounds
|
|
708个具有抗菌活性化合物的独特集合，是医药研究的优良工具库和药物筛选的有效载体；
|
|
L2130
|
抗癌细胞代谢库
|
|
1280 compounds
|
|
1280种癌细胞代谢相关的生物活性小分子化合物的特有集合，用于肿瘤相关的研究以及抗肿瘤药物的筛选，用于高通量、高内涵筛选；
|
|
L6130
|
萜类天然产物库
|
|
349 compounds
|
|
349种萜类天然产物的独特集合，可用于高通量筛选和高内涵筛选；
|
|
L3600
|
细胞因子抑制剂库
|
|
613 compounds
|
|
613个与细胞因子紧密相关的化合物集合，是高通量、高内涵筛选的良好载体；
|
|
L8500
|
HIF-1化合物库
|
|
1352 compounds
|
|
1352个HIF-1相关小分子的独特集合，可用于缺血性疾病、癌症等相关领域的药物开发和药理研究；
|
|
L6700
|
抗癌天然产物库
|
|
1471 compounds
|
|
1471种已知活性天然产物的独特集合，是肿瘤药物开发、抗癌先导化合物筛选等领域的有力工具，可用于HTS和HCS。
|
|
L2191
|
抗乳腺癌化合物库
|
|
1965 compounds
|
|
1965种与乳腺癌相关的化合物，可以用于抗乳腺癌药物研发和药理研究；
|
|
L7600
|
趋化因子抑制剂库
|
|
59 compounds
|
|
59种趋化因子或其受体抑制剂的独特集合，可用于高通量筛选和高内涵筛选；
|
|
DP9100
|
CB1-2化合物库
|
|
|
|
|
|
CL0140
|
BTK inhibitor kit
|
|
|
|
|
|
CL0122
|
ACE inhibitor kit
|
|
|
|
|
|
CL0115
|
Proton Pump inhibitor kit
|
|
|
|
|
|
CL0127
|
NOS inhibitor kit
|
|
|
|
|
|
CL0098
|
HER2 inhibitor kit
|
|
|
|
|
|
CL0128
|
HMGCR inhibitor kit
|
|
|
|
|
|
CL0150
|
DNA Methyltransferase/Demethylase inhibitor kit
|
|
|
|
|
|
CL0138
|
Carbonic Anhydrase inhibitor kit
|
|
|
|
|
|
CL0134
|
p53 inhibitor/reactivator kit
|
|
|
|
|
|
CL0147
|
c-FMS inhibitor kit
|
|
|
|
|
|
CL0099
|
RAR/RXR agonist kit
|
|
|
|
|
|
CL0117
|
DPP4 inhibitor kit
|
|
|
|
|
|
CL0136
|
ATM/ATR inhibitor kit
|
|
|
|
|
|
CL0088
|
Angiotensin Receptor inhibitor kit
|
|
|
|
|
|
CL0148
|
LPL Receptor antagonist/agonist kit
|
|
|
|
|
|
L1010
|
FDA上市及药典收录分子库
|
|
3158 compounds
|
|
3158个上市及药典分子集合，可用于高通量筛选和高内涵筛选；
|
|
L9860
|
抗抑郁症化合物库
|
|
1181 compounds
|
|
1181种与抑郁症相关的化合物，可以用于高通量和高内涵筛选
|
沪公网安备 31010602006700号
