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Gadobutrol Monohydrate

Gadobutrol Monohydrate

产品编号 T8406L   CAS 198637-52-4
别名: Gd-DO3A-butrol

Gadobutrol is a medicinal product used in diagnostic magnetic resonance imaging (MRI) in adults and children. It provides contrast enhancement during cranial, spinal, breast, or other investigations. In the central nervous system, Gadobutrol works by highlighting any areas with disrupted blood brain barrier (BBB) and/or abnormal vascularity. In breast tissue, Gadobutrol exposes the presence and extent of malignant breast disease. Similarly, gadobutrol is also used in contrast-enhanced magnetic resonance angiography (CE-MRA) for the diagnosis of stroke, detection of tumor perfusion, and presence of focal cerebral ischemia.

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Gadobutrol Monohydrate Chemical Structure
Gadobutrol Monohydrate, CAS 198637-52-4
规格 价格/CNY 货期 数量
25 mg ¥ 10,600 待询

Gadobutrol Monohydrate 的其他形式现货产品:

Gadobutrol
其他形式的 Gadobutrol Monohydrate:
药物设计专题培训
千万补贴 助力科研
BCA蛋白浓度测定试剂盒限时半价
产品目录号及名称: Gadobutrol Monohydrate (T8406L)
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参考文献
产品描述 Gadobutrol is a medicinal product used in diagnostic magnetic resonance imaging (MRI) in adults and children. It provides contrast enhancement during cranial, spinal, breast, or other investigations. In the central nervous system, Gadobutrol works by highlighting any areas with disrupted blood brain barrier (BBB) and/or abnormal vascularity. In breast tissue, Gadobutrol exposes the presence and extent of malignant breast disease. Similarly, gadobutrol is also used in contrast-enhanced magnetic resonance angiography (CE-MRA) for the diagnosis of stroke, detection of tumor perfusion, and presence of focal cerebral ischemia.
别名 Gd-DO3A-butrol
分子量 622.73
分子式 C18H33GdN4O10
CAS No. 198637-52-4

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

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TargetMol Library Books参考文献

1. Melsaether AN, Kim E, Mema E, Babb J, Kim SG. Preliminary study: Breast cancers can be well seen on 3T breast MRI with a half-dose of gadobutrol. Clin Imaging. 2019 Jun 27;58:84-89. doi: 10.1016/j.clinimag.2019.06.014. [Epub ahead of print] PubMed PMID: 31279989. 2. Cheung HMC, Karanicolas PJ, Coburn N, Law C, Milot L. Late Gadolinium Hyperintensity of Suspected Colorectal Liver Metastases on Gadofosveset-Enhanced Magnetic Resonance Imaging: A Predictor of Benignity and a Potential Problem-Solving Tool. Can Assoc Radiol J. 2019 Jul 1. pii: S0846-5371(19)30011-7. doi: 10.1016/j.carj.2019.03.006. [Epub ahead of print] PubMed PMID: 31272725. 3. Kim YS, Kim M, Choi SH, You SH, Yoo RE, Kang KM, Yun TJ, Lee ST, Moon J, Shin YW. Altered Vascular Permeability in Migraine-associated Brain Regions: Evaluation with Dynamic Contrast-enhanced MRI. Radiology. 2019 Jul 2:182566. doi: 10.1148/radiol.2019182566. [Epub ahead of print] PubMed PMID: 31264949. 4. McDonald JS, Hunt CH, Kolbe AB, Schmitz JJ, Hartman RP, Maddox DE, Kallmes DF, McDonald RJ. Acute Adverse Events Following Gadolinium-based Contrast Agent Administration: A Single-Center Retrospective Study of 281 945 Injections. Radiology. 2019 Jul 2:182834. doi: 10.1148/radiol.2019182834. [Epub ahead of print] PubMed PMID: 31264948.

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请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。

母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。

体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。

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Keywords

Gadobutrol Monohydrate 198637-52-4 Gd-DO3A-butrol Gadobutrol Inhibitor inhibitor inhibit

 

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