Powder: -20°C for 3 years | In solvent: -80°C for 1 year
D-Glutamine 是有细胞渗透性谷氨酰胺的 D 型立体异构体,是标准遗传密码编码的20种氨基酸之一。
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
25 mg | ¥ 289 | 现货 | ||
50 mg | ¥ 413 | 现货 | ||
100 mg | ¥ 538 | 现货 | ||
200 mg | ¥ 788 | 现货 | ||
500 mg | ¥ 1,320 | 现货 | ||
1 mL * 10 mM (in H2O) | ¥ 168 | 现货 |
产品描述 | D-glutamine, an D type stereoisomer of glutamine, is one of the 20 amino acids which is encoded by the standard genetic code. |
体外活性 | In catabolic states of injury and illness, glutamine becomes conditionally-essential (requiring intake from food or supplements). Glutamine is the most abundant naturally occurring, non-essential amino acid in the human body and one of the few amino acids that can directly cross the blood–brain barrier. [1] Glutamine is a key pharmaconutrient in the body's response to stress and injury. Glutamine exerts its protective effects via multiple mechanisms, including direct protection of cells and tissue from injury, attenuation inflammation, and preservation of metabolic function. [1] |
体内活性 | Glutamine shows the greatest benefit when administered at doses greater than 0.35 g/kg/day, with optimal benefit potentially occurring at 0.5 g/kg/day. [2] |
细胞实验 | Effect of D-Glutamine and glutaminase inhibitor on acetaldehyde-induced permeability. Caco-2 cell monolayers are incubated for 4 h without or with acetaldehyde (600 μM) and L-Glutamine or D-Glutamine (2 mM) in the absence or presence of 6-diazo-5-oxo-L-norleucine (DON). Transepithelial electrical resistance (TER) and FITC-inulin flux are measured. Values are means±SE (n=6)[2]. |
分子量 | 146.14 |
分子式 | C5H10N2O3 |
CAS No. | 5959-95-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: Insoluble
H2O: 10 mM
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
H2O | 1 mM | 6.8428 mL | 34.2138 mL | 68.4275 mL | 171.0688 mL |
5 mM | 1.3686 mL | 6.8428 mL | 13.6855 mL | 34.2138 mL | |
10 mM | 0.6843 mL | 3.4214 mL | 6.8428 mL | 17.1069 mL |
中药材名称 | 中药材拉丁名 | 性 | 味 | 归经 |
枸杞叶 | Lycium barbarum L. | 凉 | 苦, 甘 | 肝, 脾 |
方剂名称 | 处方组成 | 剂型 | 处方来源 |
干地黄丸6 | 枸杞叶 | 丸剂 | 《普济方》卷三十一。 |
黑豆羹 | 黑豆,淡竹叶,枸杞叶 | 羹剂 | 《圣惠》卷九十六。 |
麻仁汤1 | 火麻仁,枸杞叶,干姜,肉桂,甘草 | 汤剂 | 《圣济总录》卷八十八。 |
白虎丹 | 车前草,九里香,马蹄,枸杞叶,雁稜菜 | 敷剂 | 《景岳全书》卷六十四。 |
蒴藋汤5 | 蒴藋,槐枝,杨柳枝,桃枝,枸杞叶,淡豆豉,葱白 | 汤剂 | 《圣惠》卷九。 |
枸杞叶羹 | 枸杞叶,青蒿,葱白,豉 | 羹剂 | 《圣惠》卷九十七。 |
枸杞汤8 | 枸杞叶,天花粉,石膏,黄连,甘草 | 汤剂 | 《千金》卷二十一。 |
点眼枸杞煎 | 枸杞叶,杏仁,黄连,轻粉,青盐 | 点眼剂 | 《圣惠》卷三十二。 |
枸杞汤4 | 枸杞叶,干姜,桂心,甘草,火麻仁 | 汤剂 | 《外台》卷十七引《古今录验》。 |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
D-glutamine 5959-95-5 Apoptosis Autophagy Metabolism Neuroscience GluR Endogenous Metabolite Ferroptosis Mitophagy inhibit D glutamine Dglutamine D-Glutamine Mitochondrial Autophagy Inhibitor inhibitor