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Cat. No. | Product Name | Target | Signaling Pathways |
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T80294 |
GLK-19
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GLK-19是一种具抗大肠杆菌活性的抗菌肽(MIC: 10 μM)。 | |||
T9470 |
HPK1-IN-7
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MAPK | MAPK |
HPK1-IN-7 是一种口服有活性的、有效的HPK1(造血祖细胞激酶1, MAP4K1) 抑制剂,其IC50值为2.6 nM,具有强大的家族及激酶组选择性。它对 IRAK4 (59 nM) 和 GLK (140 nM) 具有选择性。当它与抗 PD1联合使用时,对 MC38 同基因肿瘤模型表现出极大的疗效。 | |||
T61437 |
HPK1-IN-26
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HPK1-IN-26, a novel compound, is a potent inhibitor of both HPK1 and GLK. This small molecule exhibits promise in aiding the study of animal pathogen infection [1]. |
Cat. No. | Product Name | Species | Expression System |
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TMPY-04394 |
Glucokinase Protein, Human, Recombinant
glucokinase (hexokinase 4),HXKP,MODY2,FGQTL3,LGLK,H... |
Human | E. coli |
Glucokinase belongs to the bacterial glucokinase family. Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. Alternative splicing of this gene results in three tissue-specific forms of glucokinase, one found in pancreatic islet beta cells and two found in liver. The protein localizes to the outer membrane of mitochondria. In contrast to other forms of hexokinase, this enzyme is not inhibited by its product glucose-6-phosphate but ... |