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Search Results for " c-17 "

Targets Recommended: Others

35

抑制剂 & 化合物

7

天然产物

1

TargetMol 试剂盒

46

重组蛋白

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Cat. No.	Product Name	Form	Specificity Of Inhibition
CL0141	Notch pathway inhibitor kit Notch pathway inhibitor kit

TargetMol 试剂盒

Notch pathway inhibitor kit

Cat.No: CL0141

Cat. No.	Product Name	Target	Signaling Pathways
T39392L	C-Type Natriuretic Peptide (1-22) acetate（human） C-Type Natriuretic Peptide (CNP) (1-22), human acetate(1966153-17-2 Free base)	Others	Others
	C-Type Natriuretic Peptide (CNP) (1-22), human acetate 是一种利钠肽受体 B (NPR-B) 的激动剂，一种内皮衍生的松弛剂和生长抑制因子。 C-Type Natriuretic Peptide (CNP) (1-22), human acetate 抑制由组胺和 5-HT 或直接由毛喉素刺激的 cAMP 合成。
T38181	C17 Lactosylceramide (d18:1/17:0)
	C17 Lactosylceramide is a naturally occurring sphingolipid that has been found in human brain metastases of lung adenocarcinomas but not in healthy brain tissue.
T38182	C17 Sphingomyelin (d18:1/17:0) C17 Sphingomyelin (d18:1/17:0)
	C17 Sphingomyelin is a synthetic derivative of sphingomyelin that has been used as an internal standard for the quantification of sphingomyelin.
T37437	C17 Ceramide (d18:1/17:0)
	C17 Ceramide is a synthetic ceramide that contains a non-natural C17:0 fatty acid acylated to sphingosine. It has been used as a marker of arylsulfatase A and sphingolipid activator B activity in patients undergoing enzyme replacement therapy for the genetic disease metachromatic leukodystrophy.
T37438	C17 Globotriaosylceramide (d18:1/17:0) C17 Globotriaosylceramide (d18:1/17:0)
	C17 Globotriaosylceramide is a sphingolipid that has been used as an internal standard for the quantification of globotriaosylceramides in plasma and urine from patients with Fabry disease by GC-MS.
T79142	c-Met-IN-17	c-Met/HGFR	Tyrosine Kinase/Adaptors
	c-Met-IN-17，一种高效c-Met激酶抑制剂，IC50为0.031μM，适用于癌症治疗研究。
T9689	M4205	c-Kit	Tyrosine Kinase/Adaptors
	M4205 是一种 c-Kit 抑制剂，对外显子 11、13、17 中的 c-Kit 突变具有高活性。
T61589	c-Fms-IN-13	c-Fms	Tyrosine Kinase/Adaptors
	c-Fms-IN-13 (compound 14) 是有效的 FMS 激酶抑制剂（IC50= 17 nM）。c-Fms-IN-13 是一种作抗炎剂。
T6039	TAK-285 TAK285,TAK 285	EGFR; MEK; HER; Aurora Kinase	Angiogenesis; Cell Cycle/Checkpoint; Chromatin/Epigenetic; JAK/STAT signaling; MAPK; Tyrosine Kinase/Adaptors
	TAK-285 是一种新型 HER2 和 EGFR(HER1) 双重抑制剂，IC50 分别为 17 和 23 nM。它可穿过血脑屏障，有抗肿瘤活性，对 HER1/2 的选择性是 HER4 的 10 倍以上。
T73457	DN-1289	DNA Alkylation	DNA Damage/DNA Repair
	DN-1289 是一种可口服可通过血脑屏障且具有选择性高效性的抑制剂，对双亮氨酸拉链激酶 (DLK）的 IC50 值为17 nM，对亮氨酸拉链轴承激酶 (LZK）的 IC50 值为 40 nM。DN-1289 对小鼠模型中视神经挤压 (ONC) 诱导的 p-c-Jun 有显著的抑制作用。
T75239	c-Myc inhibitor 10
	c-Myc inhibitor10 (compound 17) 是 c-myc 的抑制剂，表现出一定的的细胞效力，与甲基化的 morpholine 氮的通透性增加一致。
T35944	15-keto-17-phenyl trinor Prostaglandin F2α ethyl amide 15-keto-17-phenyl trinor Prostaglandin F2α ethyl amide
	Bimatoprost is the Allergan trade name for 17-phenyl trinor prostaglandin F2α ethyl amide (17-phenyl trinor PGF2α ethyl amide), an F-series PG analog which has been approved for use as an ocular hypotensive drug. Oxidation of the C-15 hydroxyl group produces 15-keto-17-phenyl trinor PGF2α ethyl amide. 15-keto-17-phenyl trinor PGF2α ethyl amide is a potential metabolite of 17-phenyl trinor PGF2α ethyl amide when 17-phenyl trinor PGF2α ethyl amide is administered to intact animals. No pharmacologi...
T36913	17-Epiestriol
	17-Epiestriol is a metabolite of estrone .1It is formed from estroneviaa 16α-hydroxy estrone intermediate by reduction of the C-17 ketone. 17-Epiestriol binds to estrogen receptor α (ERα) and ERβ with relative binding affinities of 29 and 80 compared with 17β-estradiol .2 1.Brinton, L.A., Trabert, B., Anderson, G.L., et al.Serum estrogens and estrogen metabolites and endometrial cancer risk among postmenopausal womenCancer Epidemiol. Biomarkers Prev.25(7)1081-1089(2016) 2.Kuiper, G.G.J.M., Lemme...
T80245	LL-37(17-32)
	LL-37(17-32)为具有生物活性的肽段，为LL-37抗菌肽C末端结构域源自的活性片段。报道显示，LL-37(17-32)能逆转癌细胞系中ABCG2介导的多药耐药性。
T73303	BTK-IN-17
	BTK-IN-17是一种选择性且具有BTK 抑制剂，IC50值为 13.7 nM。BTK-IN-17 降低 p-BTKY223和 p-PLCγ2Y1217的表达。BTK-IN-17 具有抗炎作用。
T37463	CAY10704
	CAY10704 is a potent inhibitor of hepatitis C virus (HCV) infection (EC50 = 17 nM) that displays low cytotoxicity of virally-infected human hepatoma Huh7.5.1 cells (CC50 = 21.3 μM). It displays good pharmacokinetics in mice when delivered intraperitoneally, with preferential liver distribution without significant hepatotoxicity. CAY10704 is selective for HCV over dengue virus (EC50 = 4.62 μM).
T81451	PKCd (8-17)
	PKCd (8-17) 是源自蛋白激酶 C (PKC)d V1 结构域的生物活性肽。它能抑制由佛波醇 12-肉豆蔻酸酯 13-乙酸酯 (PMA) 诱导的 PKCd 易位和激活。此外，PKCd (8-17) 在降低心脏和脑细胞缺血损伤、促进成纤维细胞增殖、以及抑制小鼠移植冠状动脉疾病方面具有潜在应用。
T37996	17-phenyl trinor Prostaglandin E2 ethyl amide 17-phenyl trinor Prostaglandin E2 ethyl amide
	17-phenyl trinor PGE2 ethyl amide is derived from 17-phenyl trinor PGE2, a synthetic analog of PGE2 that acts as an agonist of EP1 and EP3 receptors in mice (Ki = 14 and 3.7 nM, respectively) and EP1, EP3, and EP4 in rats (Ki = 25, 4.3, and 54 nM, respectively). 17-phenyl trinor PGE2 causes contraction of guinea pig ileum at a concentration of 11 μM and is 4.4 times more potent than PGE2 as an antifertility agent in hamsters. Modification of the C-1 carboxyl group to an ethyl amide serves to inc...
T71933	GNE-3500
	GNE-3500 is a Potent, Selective, and Orally Bioavailable Retinoic Acid Receptor-Related Orphan Receptor C (RORc or RORγ) Inverse Agonist. Retinoic acid receptor-related orphan receptor C (RORc, RORγ, or NR1F3) is a nuclear receptor that plays a major role in the production of interleukin (IL)-17. Considerable efforts have been directed toward the discovery of selective RORc inverse agonists as potential treatments of inflammatory diseases such as psoriasis and rheumatoid arthritis. GNE-3500 poss...
T71552	ASC-JM-17
	ASC-JM-17 is an activator of both Nrf1 and Nrf2 proteins. ASC-JM17 acts on Nrf1, Nrf2 and Hsf1 to increase the expression of proteasome subunits, antioxidant enzymes and molecular chaperones. ASC-JM17 ameliorates toxicity of the mutant androgen receptor (AR) responsible for SBMA in cell, fly and mouse models. Knockdown of the Drosophila Nrf1 and Nrf2 ortholog cap ‘n’ collar isoform-C, but not Hsf1, blocks the protective effect of ASC-JM17 on mutant AR-induced eye degeneration in flies.
T37939	N-Desethyl Bimatoprost 17-phenyl trinor Prostaglandin F2α amide
	N-Desethyl Bimatoprost (17-phenyl trinor PGF2α amide) is an F-series PG analog in which the C-1 carboxyl group has been modified to an unsubstituted amide. PG esters have been shown to have ocular hypotensive activity. PG N-ethyl amides were recently introduced as alternative PG hypotensive prodrugs. Although it has been claimed that PG amides are not converted to the free acids in vivo, studies have shown that bovine and human corneal tissue converts the amides of various PGs to the free acids ...
T37488	10(S),17(S)-DiHDHA
	Protectin D1 (also known as neuroprotectin D1 when produced in neuronal tissues) is a DHA-derived dihydroxy fatty acid that exhibits potent protective and anti-inflammatory activities. 10(S),17(S)-DiHDHA is a DHA metabolite, also referred to as protectin DX (PDX). It is produced by an apparent double lipoxygenase (LO)-mediated reaction in murine peritonitis exudates, in suspensions of human leukocytes, or by soybean 15-LO incubated with DHA. It differs from protectin D1 with respect to the stere...
T37934	15-keto-17-phenyl trinor Prostaglandin F2α 15-keto-17-phenyl trinor Prostaglandin F2α
	Bimatoprost is an F-series prostaglandin (PG) analog which has been approved for use as an ocular hypotensive drug. Oxidation of the C-15 hydroxyl group and amide hydrolysis of Bimatoprost produces 15-keto-17-phenyl trinor PGF2α. 15-keto-17-phenyl trinor PGF2α is a potential metabolite of bimatoprost when administered to animals. 15-keto PG analogs are potential minor impurities in commercial preparations of their corresponding bulk drug compounds. Although much less potent that the parent compo...
T37206	CCK (27-33) (non-sulfated)
	CCK (27-33) is a C-terminal fragment of CCK , a peptide hormone found in the intestine and brain that stimulates digestion, mediates satiety, and is involved in anxiety. Non-sulfated CCK (27-33) inhibits binding of [3H]naloxone in rat cerebellum membranes (IC50 = 4 uM) and inhibits electrically-stimulated contraction of isolated guinea pig ileum (IC50 = 17 uM), an effect that can be reversed by naloxone. Unlike sulfated CCK (27-33), the non-sulfated form does not reduce exploratory behavior in m...
T73814	cis-Lomibuvir
	cis-Lomibuvir (cis-VX-222) 是 Lomibuvir 的顺式异构体。Lomibuvir (VX-222) 是一种选择性的非核苷聚合酶抑制剂，靶向丙型肝炎病毒 NS5B 聚合酶 (RdRp) 的拇指口袋 2，Kd 为 17 nM。Lomibuvir 抑制 1b/Con1 型 HCV 亚基因组复制子，EC50为 5.2 nM。Lomibuvir 优先抑制延长的 RNA 合成，而非从头合成的 RNA。
T36731	Cholesteryl Heptadecanoate
	Cholesteryl heptadecanoate is a cholesterol ester (CE) formed by the condensation of cholesterol with heptadecanoic acid, a C-17 saturated fatty acid that does not occur in any natural animal or vegetable fat at high concentrations. As such, it is commonly used as an internal standard for the quantification of cholesterol esters by GC- or LC-mass spectrometry. CEs are major constituents of lipoprotein particles carried in blood and accumulate in the fatty acid lesions of atherosclerotic plaques....
T70538	PD-85639
	PD-85639 is a voltage-gated sodium (Na+) channel blocker (75% in 10 min & >95% in 25 min blockage of Na+ current by 25 μM PD85,639; whole-cell patch clamp using primary rat brain neurons) that is shown to target rat brain Nav1.2 with simultaneous high- and low-affinity modes of binding (EC50 = 56 nM/40% & 20 μM/60% at pH 9.0, 5 nM/28% & 3 μM/72% at pH 7.4, against 2 nM [3H]-PD85,639 for binding rat brain synaptosomes; EC50 = 17 nM/39% & 10 μM/61% using at pH 9.0 using rat brain synaptosome membr...
T37889	BHBM
	BHBM is an acylhydrazone with antifungal activity.1,2 It is active against C. neoformans in vitro (MIC80 = 1 μg/ml).2 BHBM (0.25, 1, and 4 μg/ml) inhibits the synthesis of glucosylceramide, which is essential to fungal cell division, in C. neoformans but not J774 murine macrophages.1 In vivo, BHBM (1.2 mg/kg per day) increases survival in a mouse model of C. neoformans infection. \|1. Haranahalli, K., Lazzarini, C., Sun, Y., et al. SAR studies on aromatic acylhydrazone-based inhibitors of fungal...
T38269	Purfalcamine
	Purfalcamine is an orally active, selective Plasmodium falciparum calcium-dependent protein kinase 1 (PfCDPK1) inhibitor with an IC50 of 17 nM and an EC50 of 230 nM. Purfalcamine has antimalarial activity and causes malaria parasites developmental arrest at the schizont stage[1][2]. Purfalcamine has low activity against Toxoplasma gondii calcium-dependent protein kinase 3 (TgCDPK3)[1]. Purfalcamine (225, 450 nM) has no effect on the parasitemia in the first 32 hours. After about 40 hours, paras...
T35772	Emestrin
	Emestrin is a mycotoxin originally isolated from E. striata that has antimicrobial, immunomodulatory, and cytotoxic activities.1,2,3,4,5 It is active against the fungi C. albicans and C. neoformans, as well as the bacteria E. coli, S. aureus, and methicillin-resistant S. aureus (MRSA; IC50s = 3.94, 0.6, 2.21, 4.55, and 2.21 μg/ml, respectively).2 Emestrin is a chemokine (C-C motif) receptor 2 (CCR2) antagonist (IC50 = 5.4 μM in a radioligand binding assay using isolated human monocytes).3 Emestr...
T36215	17R(18S)-EpETE
	17R(18S)-EpETE is an oxylipin and a cytochrome P450 metabolite of eicosapentaenoic acid .1,217R(18S)-EpETE is an activator of large-conductance calcium-activated potassium (BKCa) channels, increasing the potassium current amplitude by 15-fold in isolated rat cerebral artery vascular smooth muscle cells (VSMCs) at +60 mV when used at a concentration of 50 nM.2It has negative chronotropic effects in isolated neonatal rat cardiomyocytes (NRCMs; EC50= ~1-2 nM) and prevents calcium-induced increases ...
T4620	Siramesine 西拉美新,Lu 28-179	Sigma receptor	GPCR/G Protein
	Siramesine (Lu 28-179) 是sigma-2受体激动剂，通过线粒体的不稳定溶酶体触发细胞死亡，有强大的抗癌活性。它对 sigma-2 受体具有亚纳摩尔亲和力，IC50为 0.12 nM。它对 sigma-2 受体的选择性是 sigma-1 受体的 140倍，IC50为 17 nM。
T36418	O-Desmethyl-N-deschlorobenzoyl Indomethacin
	O-Desmethyl-N-deschlorobenzoyl indomethacin is a metabolite of the non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor indomethacin .1It is formed from indomethacin in isolated rabbit hepatocytes. O-Desmethyl-N-deschlorobenzoyl indomethacin (600 μM) decreases the viability of HL-60 leukemia cells when cultured with glucose oxidase.2It has also been used in the synthesis of prostaglandin D2receptor antagonists.3 1.Evans, M.A., Papazafiratou, C., Bhat, R., et al.Indomethacin metabolism ...
T38297	Ribavirin-13C5 Ribavirin-13C5
	Ribavirin-13C5is intended for use as an internal standard for the quantification of ribavirin by GC- or LC-MS. Ribavirin is an antiviral guanosine nucleoside analog.1,2Upon entry into cells, ribavirin is metabolized to an active triphosphate form that induces viral RNA chain termination and inhibits viral polymerases. It reduces replication in a panel of seven RNA and four DNA viruses in Vero cells (EC50s = 2-95 μg/ml).3Ribavirin also reduces replication of severe acute respiratory syndrome coro...
T37741	N-hexadecanoyl-L-Homoserine lactone C16-HSL,N-palmitoyl-L-Homoserine,N-hexadecanoyl-L-Homoserine lactone
	Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density.[1] This regulatory process manifests itself with a variety of phenotypes including biofilm formation and virulence factor production.[2] Coordinated gene expression is achieved by the production, release, and detection of small diffusible signal molecules called autoinducers. The N-acylated homoserine lactones (AHLs) comprise one such class of autoinducers, each of which...

化合物

C-Type Natriuretic Peptide (1-22) acetate（human）

Cat.No: T39392L

Synonym: C-Type Natriuretic Peptide (CNP) (1-22), human acetate(1966153-17-2 Free base)

Target: Others

C17 Lactosylceramide (d18:1/17:0)

Cat.No: T38181

C17 Sphingomyelin (d18:1/17:0)

Cat.No: T38182

Synonym: C17 Sphingomyelin (d18:1/17:0)

C17 Ceramide (d18:1/17:0)

Cat.No: T37437

C17 Globotriaosylceramide (d18:1/17:0)

Cat.No: T37438

Synonym: C17 Globotriaosylceramide (d18:1/17:0)

Cat.No: T79142

Target: c-Met/HGFR

Cat.No: T9689

Target: c-Kit

Cat.No: T61589

Target: c-Fms

Cat.No: T6039

Synonym: TAK285,TAK 285

Target: EGFR, MEK, HER, Aurora Kinase

Cat.No: T73457

Target: DNA Alkylation

c-Myc inhibitor 10

Cat.No: T75239

15-keto-17-phenyl trinor Prostaglandin F2α ethyl amide

Cat.No: T35944

Synonym: 15-keto-17-phenyl trinor Prostaglandin F2α ethyl amide

Cat.No: T36913

Cat.No: T80245

Cat.No: T73303

Cat.No: T37463

Cat.No: T81451

17-phenyl trinor Prostaglandin E2 ethyl amide

Cat.No: T37996

Synonym: 17-phenyl trinor Prostaglandin E2 ethyl amide

Cat.No: T71933

Cat.No: T71552

N-Desethyl Bimatoprost

Cat.No: T37939

Synonym: 17-phenyl trinor Prostaglandin F2α amide

10(S),17(S)-DiHDHA

Cat.No: T37488

15-keto-17-phenyl trinor Prostaglandin F2α

Cat.No: T37934

Synonym: 15-keto-17-phenyl trinor Prostaglandin F2α

CCK (27-33) (non-sulfated)

Cat.No: T37206

Cat.No: T73814

Cholesteryl Heptadecanoate

Cat.No: T36731

Cat.No: T70538

Cat.No: T37889

Cat.No: T38269

Cat.No: T35772

Cat.No: T36215

Cat.No: T4620

Synonym: 西拉美新,Lu 28-179

Target: Sigma receptor

O-Desmethyl-N-deschlorobenzoyl Indomethacin

Cat.No: T36418

Cat.No: T38297

Synonym: Ribavirin-13C5

N-hexadecanoyl-L-Homoserine lactone

Cat.No: T37741

Synonym: C16-HSL,N-palmitoyl-L-Homoserine,N-hexadecanoyl-L-Homoserine lactone

Cat. No.	Product Name	Target	Signaling Pathways
TN1195	17-Hydroxy sprengerinin C 17-羟基麦冬皂苷C	BCL; Others; Caspase	Apoptosis; Others; Proteases/Proteasome
	17-Hydroxy sprengerinin C 是从黄精的根茎中分离得到的一种糖苷化合物，具有更强的抗癌活性。17-Hydroxy sprengerinin C 降低 Blc-2 和 pro-caspase3 的表达并增加 Bax 的产生。
T6S2116	Ginkgolic acid C17:1 银杏酸 C17:1,银杏酸C17:1	Phosphatase; PTEN	Metabolism; PI3K/Akt/mTOR signaling
	Ginkgolic acid C17:1 是分离自银杏叶中，通过诱导PTEN 和SHP-1酪氨酸磷酸酶抑制组成型和诱导型 STAT3 活化。它具有抗癌活性。
TN2373	(E/Z)-Ginkgolic acid C17:2 Ginkgolic Acid C17:2	Dehydrogenase	Metabolism
	(E/Z)-Ginkgolic acid C17:2 (Ginkgolic Acid C17:2) 是一种可从银杏中提取的天然产物，可靶向人二氢乳清酸脱氢酶 (DHODH).
T78473	Sphingosine (d17:1) C17 Sphingosine
	Sphingosine (d17:1) (C17 Sphingosine)是一种存在于人类皮肤中的17碳鞘脂，可被鞘氨醇激酶的磷酸化。Sphingosine C-17作为内标可用于进行鞘脂类化合物的光谱分析。
TN4784	Picraline	SGLT	GPCR/G Protein
	A series of a hydroxy substituted derivatives 21-28 at C-17 of the Picraline-type alkaloids have been derived as having potent SGLT inhibitory activity.
T36044	17-hydroxy Venturicidin A
	17-hydroxy Venturicidin A is a macrolide fungal metabolite originally isolated from Streptomyces. It has antibiotic activity against M. luteus, B. subtilis, and S. aureus and antifungal activity against V. dahlia, Fusarium, and C. tropicalis in a disc assay.
T36179	Aspulvinone O
	Aspulvinone O is a fungal metabolite that has been found in P. variotti and has antioxidant and anticancer activities.1,2 It scavenges 2,2-diphenyl-1-picrylhydrazyl radicals in a cell-free assay (IC50 = 11.6 μM).1 Aspulvinone O inhibits aspartate transaminase 1 (GOT1; Kd = 3.32 μM) and is cytotoxic to PANC-1, AsPC-1, and SW1990 pancreatic cancer cells (IC50s = 20.54-26.8 μM).2 It reduces the oxygen consumption rate (OCR) and induces apoptosis in SW1990 cells. Aspulvinone O (2.5 and 5 mg/kg) redu...

天然产物

17-Hydroxy sprengerinin C

Cat.No: TN1195

Synonym: 17-羟基麦冬皂苷C

Target: BCL, Others, Caspase

Ginkgolic acid C17:1

Cat.No: T6S2116

Synonym: 银杏酸 C17:1,银杏酸C17:1

Target: Phosphatase, PTEN

(E/Z)-Ginkgolic acid C17:2

Cat.No: TN2373

Synonym: Ginkgolic Acid C17:2

Target: Dehydrogenase

Sphingosine (d17:1)

Cat.No: T78473

Synonym: C17 Sphingosine

Cat.No: TN4784

Target: SGLT

17-hydroxy Venturicidin A

Cat.No: T36044

Cat.No: T36179

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-03248	TARC Protein, Rhesus, Recombinant (His) chemokine (C-C motif) ligand ...	Rhesus	Baculovirus Insect Cells
	TARC Protein, Rhesus, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 9.56 kDa and the accession number is Q8HYP9.
TMPY-02083	TARC Protein, Human, Recombinant chemokine (C-C motif) ligand ...	Human	Baculovirus Insect Cells
	TARC Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 8 kDa and the accession number is Q92583-1.
TMPY-02061	TARC Protein, Human, Recombinant (His) SCYA17,ABCD-2,chemokine ...	Human	Baculovirus Insect Cells
	TARC Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 9.5 kDa and the accession number is Q92583-1.
TMPY-02362	TARC Protein, Mouse, Recombinant Abcd-2,Scya17,Scya17...	Mouse	Baculovirus Insect Cells
	TARC Protein, Mouse, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 8.2 kDa and the accession number is Q9WUZ6.
TMPY-04984	CXCL17 Protein, Human, Recombinant (His) Dcip1,UNQ473,DMC,VCC1,	Human	P. pastoris (Yeast)
	Chemokine (C-X-C motif) ligand 17 (CXCL17) is the latest member of the chemokine family. CXCL17 is a potential oncogene and promising therapeutic target, is an independent biomarker of poor prognosis in patients with breast cancer, and can promote proliferation and migration of breast cancer cells in vitro and in vivo. CXCL17 is expressed in a variety of cancers and promotes tumor progression by recruiting myeloid-derived suppressor cells (MDSCs). CXCL17 attenuates IMQ-induced psoriasis-like ski...
TMPK-00703	IL-17Rc Protein, Human, Recombinant (hFc) IL-17 receptor C,IL-17R<...	Human	HEK293 Cells
	IL-17RC (interleukin-17 receptor-like) gene codes for a transmembrane protein, the full length of which inhibits apoptosis in prostate cancer cells. IL-17RC gene transcribes over a dozen different splice variants of mRNA. IL-17RC protein isoforms are differentially expressed in prostatic cells and cancer tissues and may play a negative or positive role in the initiation and progression of prostate cancer.
TMPY-00044	CYTL1 Protein, Human, Recombinant (mFc) C4orf4,C17,cytokine-like...	Human	HEK293 Cells
	Cytokine-like protein 1 (CYTL1) is a small widely expressed secreted protein lacking significant primary sequence homology to any other known protein. Cytokine-like 1 (CYTL1) is a novel potential cytokine that was first identified in CD34(+) cells derived from bone marrow and cord blood, and it was also found using our immunogenomics strategy. CYTL1 expression appears to be highest in the hematopoietic system and in chondrocytes; however, maintenance of cartilage in mouse models of arthritis is ...
TMPY-02573	IL-17RC Protein, Human, Recombinant (aa 1-454, His) IL17RL,interleukin 17 receptor	Human	Baculovirus Insect Cells
	IL-17RC Protein, Human, Recombinant (aa 1-454, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 49.6 kDa and the accession number is Q8NAC3-3.
TMPY-02691	IL-17RC Protein, Human, Recombinant(aa 1-454, hFc) IL17RL,interleukin 17 receptor	Human	HEK293 Cells
	IL-17RC Protein, Human, Recombinant(aa 1-454, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 75.3 kDa and the accession number is Q8NAC3-3.
TMPH-00485	CCL17 Protein, Canine, Recombinant (His & KSI) CC chemokine TARC,Small-...	Canine	E. coli
	CCL17 Protein, Canine, Recombinant (His & KSI) is expressed in E. coli.
TMPJ-01261	PPP1R14A Protein, Human, Recombinant (His) 17 kDa PKC-Potentiated Inhibitory Protein ...	Human	E. coli
	Protein Phosphatase 1 Regulatory Subunit 14A (PPP1R14A) belongs to the PP1 inhibitor family. PPP1R14A is mapped to chromosome 19q13.13-q13.2. PPP1R14A binds directly to protein kinase C and casein kinase I. Meantime, PPP1R14A is a phosphorylation-dependent inhibitor of smooth muscle myosin phosphatase. PPP1R14A is the inhibitor of PPP1CA. When phosphorylated, PPP1R14A has over 1000-fold higher inhibitory activity, creating a molecular switch for regulating the phosphorylation status of PPP1CA su...
TMPH-01439	Human herpesvirus 1 (HHV-1) (strain 17) Envelope glycoprotein C (His & Myc)	HHV-1	E. coli
	Human herpesvirus 1 (HHV-1) (strain 17) Envelope glycoprotein C (His & Myc) is expressed in E. coli.
TMPY-00423	FGFR2 Protein, Human, Recombinant (alpha IIIb, hFc) BFR-1,KGFR,TK25,JWS,ECT1,K-SAM,FGFR2 α(IIIb),C<...	Human	HEK293 Cells
	FGFR2 Protein, Human, Recombinant (alpha IIIb, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 66.3 kDa and the accession number is P21802-17.
TMPJ-00636	CTLA-4 Protein, Cynomolgus, Recombinant (His) Cytotoxic T-lymphocyte protein 4,...	Cynomolgus	HEK293 Cells
	CTLA-4 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 17-25 KDa and the accession number is G7PL88.
TMPK-00676	Osteopontin Protein, Human, Recombinant (aa 17-300, His) BSP-1,Nephropontin,BNSP,ETA-1,OPN,Bone sialoprotein 1,BSPI,U...	Human	HEK293 Cells
	Osteopontin Protein, Human, Recombinant (aa 17-300, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 34.8 kDa and the accession number is A0A024RDE6.
TMPJ-00251	IL-3R alpha/CD123 Protein, Mouse, Recombinant (aa 17-331, His) IL-3 receptor subunit alpha,IL-3R subunit α,Interle...	Mouse	HEK293 Cells
	IL-3R alpha/CD123 Protein, Mouse, Recombinant (aa 17-331, His) is expressed in HEK293 mammalian cells with C-8xHis tag. The predicted molecular weight is 50-65 KDa and the accession number is P26952.
TMPK-00366	Siglec-10 Protein,Human,Recombinant (aa 17-546, His) SLG2,SIGLEC10,MGC126774,PRO940	Human	HEK293 Cells
	Siglec-10 Protein,Human,Recombinant (aa 17-546, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 59.2 kDa and the accession number is Q96LC7-1.
TMPK-00648	LILRB1/CD85j/ILT2 Protein, Rhesus macaque, Recombinant (aa 17-456, hFc) MIR7,ILT-2,LILRB1,ILT2,XXbac-BCX85G21.4,LI...	Rhesus	HEK293 Cells
	LILRB1/CD85j/ILT2 Protein, Rhesus macaque, Recombinant (aa 17-456, hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 74.5 kDa and the accession number is F7H3G7.
TMPJ-00046	IL-17F Protein, Human, Recombinant IL17F,白介素,IL-17F,Interleukin-17F,...	Human	E. coli
	Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mice. Today, IL-17 represents a family of structurally related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers. IL-17F also regulates cartilage mat...
TMPJ-01237	IL-17D Protein, Human, Recombinant IL17D,Interleukin-17D,IL-17D	Human	E. coli
	The Interleukin-17 family proteins, comprising six members (IL-17, IL-17B through IL-17F),are secreted, structurally related proteins that share a conserved cysteine-knot fold near the C-terminus, but have considerable sequence divergence at the N-terminus. IL-17 family proteins are proinflammatory cytokines that induce local cytokine production and are involved in the regulation of immune functions. Among IL-17 family members, IL-17D is most closely related to IL-17B, sharing 27% aa sequence ho...
TMPH-02498	AKR1C3 Protein, Mouse, Recombinant (His & Myc) Aldo-keto reductase family 1 member C13	Mouse	E. coli
	Catalyzes the dehydrogenation of 17-beta-hydroxysteroids. May also exhibit significant activity with a variety of cyclic and alicyclic alcohols. Uses both NAD and NADP, but the activity is much greater with NAD than with NADP. AKR1C3 Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 44.5 kDa and the accession number is Q8VC28.
TMPK-00064	BCMA/TNFRSF17 Protein, Cynomolgus/Rhesus macaque, Recombinant (His) TNFRSF13A,BCMA,TNFRSF17,BCM,C...	Cynomolgus,Rhesus	HEK293 Cells
	B-cell maturation antigen (BCMA or BCM), also known as tumor necrosis factor receptor superfamily member 17 (TNFRSF17), is a protein that in humans is encoded by the TNFRSF17 gene.TNFRSF17 is a cell surface receptor of the TNF receptor superfamily which recognizes B-cell activating factor (BAFF). BCMA/TNFRSF17 Protein, Cynomolgus/Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 7.10 kDa and the accession number is A0A2K5UD...
TMPK-00825	VEGF121 Protein, Human, Recombinant (His & Avi) VPF,VEGF,VEGFA,VEGFMGC70609,血管内皮生长因子,MGC70...	Human	HEK293 Cells
	Vascular endothelial growth factor (VEGF or VEGF-A), also known as vascular permeability factor (VPF), is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. VEGF165 appears to be the most abundant and potent isoform, followed by VEGF121 and VEGF189. VEGF121 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 17 kDa and the accession number is P15692-9.
TMPK-00206	EpCAM/TROP1 Protein, Human, Recombinant (aa 24-265, hFc) ESA,TACSTD1,EGP-2,TROP1,EpCAM,EGP314,MO	Human	HEK293 Cells
	Epithelial Cellular Adhesion Molecule (EpCAM), also known as KS1/4, gp40, GA733-2, 17-1A, and TROP‑1, is a 40 kDa transmembrane glycoprotein that consists of a 242 amino acid (aa) extracellular domain with two EGF‑like repeats, a 23 aa transmembrane segment, and a 26 aa cytoplasmic domain. EpCAM/TROP1 Protein, Human, Recombinant (aa 24-265, hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 54.2 kDa and the accession number is P16422.
TMPK-00071	BCMA/TNFRSF17 Protein, Mouse, Recombinant (His & Avi) TNFRSF17,BCMA,BCM,TNFRSF13A,C...	Mouse	HEK293 Cells
	B-cell maturation antigen (BCMA or BCM), also known as tumor necrosis factor receptor superfamily member 17 (TNFRSF17), is a protein that in humans is encoded by the TNFRSF17 gene.TNFRSF17 is a cell surface receptor of the TNF receptor superfamily which recognizes B-cell activating factor (BAFF). BCMA/TNFRSF17 Protein, Mouse, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 8.5 kDa and the accession number is O88472-1.
TMPK-00826	VEGF121 Protein, Human, Recombinant (His & Avi), Biotinylated VAS,VEGFMGC70609,RP1-261G23.1,血管内皮生长因子,VEGFA,VPF,MV...	Human	HEK293 Cells
	Vascular endothelial growth factor (VEGF or VEGF-A), also known as vascular permeability factor (VPF), is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. VEGF165 appears to be the most abundant and potent isoform, followed by VEGF121 and VEGF189. VEGF121 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 17 kDa and the accession number is P15692-9.
TMPK-00207	EpCAM/TROP1 Protein, Human, Recombinant (aa 24-265, His) DIAR5,MOC31,EGP,MK1,HNPCC8,EGP314...	Human	HEK293 Cells
	Epithelial Cellular Adhesion Molecule (EpCAM), also known as KS1/4, gp40, GA733-2, 17-1A, and TROP‑1, is a 40 kDa transmembrane glycoprotein that consists of a 242 amino acid (aa) extracellular domain with two EGF‑like repeats, a 23 aa transmembrane segment, and a 26 aa cytoplasmic domain. EpCAM/TROP1 Protein, Human, Recombinant (aa 24-265, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 28.2 kDa and the accession number is P16422.
TMPK-00066	BCMA/TNFRSF17 Protein, Human, Recombinant (His & Avi), FITC-Labeled CD269,TNFRSF17,TNFRSF13A,BCMA,B	Human	HEK293 Cells
	B-cell maturation antigen (BCMA or BCM), also known as tumor necrosis factor receptor superfamily member 17 (TNFRSF17), is a protein that in humans is encoded by the TNFRSF17 gene.TNFRSF17 is a cell surface receptor of the TNF receptor superfamily which recognizes B-cell activating factor (BAFF). BCMA/TNFRSF17 Protein, Human, Recombinant (His & Avi), FITC-Labeled is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 8.9 kDa and the accession number is Q0222...
TMPK-00069	BCMA/TNFRSF17 Protein, Human, Recombinant (His & Avi), Biotinylated BCMA,BCM,CD269,TNFRSF17,...	Human	HEK293 Cells
	B-cell maturation antigen (BCMA or BCM), also known as tumor necrosis factor receptor superfamily member 17 (TNFRSF17), is a protein that in humans is encoded by the TNFRSF17 gene.TNFRSF17 is a cell surface receptor of the TNF receptor superfamily which recognizes B-cell activating factor (BAFF). BCMA/TNFRSF17 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 8.9 kDa and the accession number is Q0222...
TMPK-00068	BCMA/TNFRSF17 Trimer Protein, Human, Recombinant (His & Avi), Biotinylated CD269,TNFRSF17,BCMA,TNFRSF13A,B	Human	HEK293 Cells
	B-cell maturation antigen (BCMA or BCM), also known as tumor necrosis factor receptor superfamily member 17 (TNFRSF17), is a protein that in humans is encoded by the TNFRSF17 gene.TNFRSF17 is a cell surface receptor of the TNF receptor superfamily which recognizes B-cell activating factor (BAFF). BCMA/TNFRSF17 Trimer Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 29.5 kDa and the accession number ...
TMPK-00065	BCMA/TNFRSF17 Trimer Protein, Human, Recombinant (His & Avi) BCM,TNFRSF13A,TNFRSF17,CD269,B	Human	HEK293 Cells
	B-cell maturation antigen (BCMA or BCM), also known as tumor necrosis factor receptor superfamily member 17 (TNFRSF17), is a protein that in humans is encoded by the TNFRSF17 gene.TNFRSF17 is a cell surface receptor of the TNF receptor superfamily which recognizes B-cell activating factor (BAFF). BCMA/TNFRSF17 Trimer Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 29.5 kDa and the accession number is Q02223.
TMPK-00072	BCMA/TNFRSF17 Protein, Mouse, Recombinant (His & Avi), Biotinylated TNFRSF13A,TNFRSF17,BCM,BCMA,C...	Mouse	HEK293 Cells
	B-cell maturation antigen (BCMA or BCM), also known as tumor necrosis factor receptor superfamily member 17 (TNFRSF17), is a protein that in humans is encoded by the TNFRSF17 gene.TNFRSF17 is a cell surface receptor of the TNF receptor superfamily which recognizes B-cell activating factor (BAFF). BCMA/TNFRSF17 Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 8.5 kDa and the accession number is O8847...
TMPK-00680	EpCAM/TROP1 Protein, Cynomolgus/Rhesus macaque, Recombinant (His) EGP40,EGP314,CD326,EGP,KSA,HNPCC8...	Cynomolgus,Rhesus	HEK293 Cells
	Epithelial Cellular Adhesion Molecule (EpCAM), also known as KS1/4, gp40, GA733-2, 17-1A, and TROP‑1, is a 40 kDa transmembrane glycoprotein that consists of a 242 amino acid (aa) extracellular domain with two EGF‑like repeats, a 23 aa transmembrane segment, and a 26 aa cytoplasmic domain. EpCAM/TROP1 Protein, Cynomolgus/Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 28.5 kDa and the accession number is Q1WER1.
TMPK-00205	EpCAM/TROP1 Protein, Human, Recombinant (aa 24-265, His & Avi), Biotinylated EGP40,TROP1,EGP314,MIC18,DIAR5,ESA,KSA,TAC...	Human	HEK293 Cells
	Epithelial Cellular Adhesion Molecule (EpCAM), also known as KS1/4, gp40, GA733-2, 17-1A, and TROP‑1, is a 40 kDa transmembrane glycoprotein that consists of a 242 amino acid (aa) extracellular domain with two EGF‑like repeats, a 23 aa transmembrane segment, and a 26 aa cytoplasmic domain. EpCAM/TROP1 Protein, Human, Recombinant (aa 24-265, His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 30.1 kDa and the accession number is P1...
TMPJ-00060	IL-25/IL17E Protein, Human, Recombinant (His) 白细胞介素,IL17E,白介素,IL-17E,IL-25,IL25,Interleu...	Human	HEK293 Cells
	Interleukin 25 (IL-25) belongs to the Interleukin 17 (IL-17) family of proteins, which is comprised of six members (IL-17, IL-17B through IL-17F). These proteins are secreted and are structurally related by sharing a conserved cysteine-knot fold near the C-terminus, but have considerable sequence divergence at the N-terminus. With the exception of IL-17B, which exists as a non-covalently linked dimer, all IL-17 family members are disulfide-linked dimers. IL-17 family proteins are pro-inflammator...
TMPH-01303	HSD17B11 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Can convert androstan-3-alpha,17-beta-diol (3-alpha-diol) to androsterone in vitro, suggesting that it may participate in androgen metabolism during steroidogenesis. May act by metabolizing compounds that stimulate steroid synthesis and/or by generating metabolites that inhibit it. Has no activity toward DHEA (dehydroepiandrosterone), or A-dione (4-androste-3,17-dione), and only a slight activity toward testosterone to A-dione. Tumor-associated antigen in cutaneous T-cell lymphoma. HSD17B11 Prot...
TMPK-00918	ADAM8/CD156a Protein, Human, Recombinant (aa 17-655, His) CD156a,ADAM 8,MGC134985,Adam8,Ms2	Human	HEK293 Cells
	A Disintegrin And Metalloproteinase (ADAM) proteases constitute a family of multifunctional, membrane-bound proteins with traditional sheddase functions. Their protumorigenic potential has been attributed to both, essential (ADAM10 and ADAM17) and 'dispensable' ADAM proteases (ADAM8, 9, 12, 15, and 19). Of specific interest in this review is the ADAM proteinase ADAM8 that has been identified as a significant player in aggressive malignancies including breast, pancreatic, and brain cancer. ADAM8/...
TMPJ-01119	GPNMB Protein, Human, Recombinant (His) Transmembrane Glycoprotein NMB,HGFIN,NMB,GPNMB,Tran...	Human	HEK293 Cells
	Osteoactivin is an intracellular glycoprotein belongs to the NMB/pMEL-17 family, which is asscociated with cell endosomal/lysomal compartments. Human Osteoactivin is a 560 amino acid type I transmembrane protein, and one alternate splice form shows a 12 amino acid insert between amino acid 339-340. An additional 206 amino acid isoform shows a mutation at position 181 that results in a 26 amino acid substitution for the C-terminal 380 amino acids. Cells knowns to express Osteoactivin include fibr...
TMPK-01385	CRTAM Protein, Canine, Recombinant (His) CRTAM,CD355 antigen,CD355	Canine	HEK293 Cells
	Class-I Restricted T Cell-Associated Molecule (CRTAM) is a protein that is expressed after T cell activation. The interaction of CRTAM with its ligand, nectin-like 2 (Necl2), is required for the efficient production of IL-17, IL-22, and IFNγ by murine CD4 T cells, and it plays a role in optimal CD8 T and NK cell cytotoxicity. CRTAM promotes the pro-inflammatory cytokine profile; therefore, it may take part in the immunopathology of autoimmune diseases such as diabetes type 1 or colitis. CRTAM Pr...
TMPK-00971	CRTAM Protein, Mouse, Recombinant (His) CRTAM,CD355,CD355 antigen	Mouse	HEK293 Cells
	Class-I Restricted T Cell-Associated Molecule (CRTAM) is a protein that is expressed after T cell activation. The interaction of CRTAM with its ligand, nectin-like 2 (Necl2), is required for the efficient production of IL-17, IL-22, and IFNγ by murine CD4 T cells, and it plays a role in optimal CD8 T and NK cell cytotoxicity. CRTAM promotes the pro-inflammatory cytokine profile; therefore, it may take part in the immunopathology of autoimmune diseases such as diabetes type 1 or colitis. CRTAM Pr...
TMPJ-00857	Thrombomodulin Protein, Mouse, Recombinant (His) Fetomodulin,Thbd,BDCA-3,Thrombomodulin,CD1...	Mouse	HEK293 Cells
	Thrombomodulin is also known as CD141 antigen and blood dendritic cell antigen 3 (BDCA3), which is encoded by the THBD gene. The deduced amino acid sequence of mouse THBD predicts a signal peptide (aa 1 to 16) and a mature chain (aa 17 to 577) that consists of the following domains: C-type lectin, EGF-like, transmembrane and cytoplasmic. Mouse THBD is corresponding to the extracellular portion of the type I membrane protein. Predominantly synthesized by vascular endothelial cells, THBD inhibits ...
TMPJ-00445	IBSP Protein, Mouse, Recombinant (His) BNSP,IBSP,Integrin binding sialoprotein,Cell bindin...	Mouse	HEK293 Cells
	Bone sialoprotein 2(IBSP) is a monomeric non‑collagenous member of the SIBLING family of extracellular matrix proteins. It is principally associated with the early stages of bone mineralization. Mouse IBSP is synthesized as a 324 amino acid (aa) precursor that contains a 16 aa signal sequence and a 308 aa mature region. The mature segment is divided into a basic N‑terminus (aa 17 ‑ 62), a central region (aa 63 ‑ 233), and an acidic C‑terminus (aa 234 ‑ 317). IBSP is highly glycosylated, sulfate...
TMPY-01187	Rac1 Protein, Human, Recombinant (GST) Rac-1,p21-Rac1,MIG5,ras-related C...	Human	Baculovirus Insect Cells
	RAC1 is a GTPase that belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. Two transcript variants encoding different isoforms have been found for RAC1 gene. RAC1 is a plasma membrane-associated small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, bind...
TMPK-01450	HLA-C*03:04&B2M&KRAS G12D (GADGVGKSAL) Monomer Protein, Human, MHC (His & Avi), Biotinylated KRAS1,MHC,K-RAS4B,KRAS,CFC2,K-RAS...	Human	HEK293 Cells
	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01451	HLA-C 03:04&B2M&KRAS G12D (GADGVGKSAL) Monomer Protein, Human, MHC (His & Avi) NS3,K-RAS4A,K-Ras 2,NS,KRAS1,RASK2,MHC,KI-RAS,KRAS,...	Human	HEK293 Cells
	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01456	HLA-C*03:04&B2M&KRAS G12D (GADGVGKSAL) Tetramer Protein, Human, MHC (His & Avi) KRAS2,NS,MHC,C-K-RAS,KRAS1,K-RAS2A,K-RAS2B...	Human	HEK293 Cells
	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.

重组蛋白

TARC Protein, Rhesus, Recombinant (His)

Cat.No: TMPY-03248

Species: Rhesus

Expression System: Baculovirus Insect Cells

TARC Protein, Human, Recombinant

Cat.No: TMPY-02083

Species: Human

Expression System: Baculovirus Insect Cells

TARC Protein, Human, Recombinant (His)

Cat.No: TMPY-02061

Species: Human

Expression System: Baculovirus Insect Cells

TARC Protein, Mouse, Recombinant

Cat.No: TMPY-02362

Species: Mouse

Expression System: Baculovirus Insect Cells

CXCL17 Protein, Human, Recombinant (His)

Cat.No: TMPY-04984

Species: Human

Expression System: P. pastoris (Yeast)

IL-17Rc Protein, Human, Recombinant (hFc)

Cat.No: TMPK-00703

Species: Human

Expression System: HEK293 Cells

CYTL1 Protein, Human, Recombinant (mFc)

Cat.No: TMPY-00044

Species: Human

Expression System: HEK293 Cells

IL-17RC Protein, Human, Recombinant (aa 1-454, His)

Cat.No: TMPY-02573

Species: Human

Expression System: Baculovirus Insect Cells

IL-17RC Protein, Human, Recombinant(aa 1-454, hFc)

Cat.No: TMPY-02691

Species: Human

Expression System: HEK293 Cells

CCL17 Protein, Canine, Recombinant (His & KSI)

Cat.No: TMPH-00485

Species: Canine

Expression System: E. coli

PPP1R14A Protein, Human, Recombinant (His)

Cat.No: TMPJ-01261

Species: Human

Expression System: E. coli

Human herpesvirus 1 (HHV-1) (strain 17) Envelope glycoprotein C (His & Myc)

Cat.No: TMPH-01439

Species: HHV-1

Expression System: E. coli

FGFR2 Protein, Human, Recombinant (alpha IIIb, hFc)

Cat.No: TMPY-00423

Species: Human

Expression System: HEK293 Cells

CTLA-4 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPJ-00636

Species: Cynomolgus

Expression System: HEK293 Cells

Osteopontin Protein, Human, Recombinant (aa 17-300, His)

Cat.No: TMPK-00676

Species: Human

Expression System: HEK293 Cells

IL-3R alpha/CD123 Protein, Mouse, Recombinant (aa 17-331, His)

Cat.No: TMPJ-00251

Species: Mouse

Expression System: HEK293 Cells

Siglec-10 Protein,Human,Recombinant (aa 17-546, His)

Cat.No: TMPK-00366

Species: Human

Expression System: HEK293 Cells

LILRB1/CD85j/ILT2 Protein, Rhesus macaque, Recombinant (aa 17-456, hFc)

Cat.No: TMPK-00648

Species: Rhesus

Expression System: HEK293 Cells

IL-17F Protein, Human, Recombinant

Cat.No: TMPJ-00046

Species: Human

Expression System: E. coli

IL-17D Protein, Human, Recombinant

Cat.No: TMPJ-01237

Species: Human

Expression System: E. coli

AKR1C3 Protein, Mouse, Recombinant (His & Myc)

Cat.No: TMPH-02498

Species: Mouse

Expression System: E. coli

BCMA/TNFRSF17 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)

Cat.No: TMPK-00064

Species: Cynomolgus,Rhesus

Expression System: HEK293 Cells

VEGF121 Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00825

Species: Human

Expression System: HEK293 Cells

EpCAM/TROP1 Protein, Human, Recombinant (aa 24-265, hFc)

Cat.No: TMPK-00206

Species: Human

Expression System: HEK293 Cells

BCMA/TNFRSF17 Protein, Mouse, Recombinant (His & Avi)

Cat.No: TMPK-00071

Species: Mouse

Expression System: HEK293 Cells

VEGF121 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00826

Species: Human

Expression System: HEK293 Cells

EpCAM/TROP1 Protein, Human, Recombinant (aa 24-265, His)

Cat.No: TMPK-00207

Species: Human

Expression System: HEK293 Cells

BCMA/TNFRSF17 Protein, Human, Recombinant (His & Avi), FITC-Labeled

Cat.No: TMPK-00066

Species: Human

Expression System: HEK293 Cells

BCMA/TNFRSF17 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00069

Species: Human

Expression System: HEK293 Cells

BCMA/TNFRSF17 Trimer Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00068

Species: Human

Expression System: HEK293 Cells

BCMA/TNFRSF17 Trimer Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00065

Species: Human

Expression System: HEK293 Cells

BCMA/TNFRSF17 Protein, Mouse, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00072

Species: Mouse

Expression System: HEK293 Cells

EpCAM/TROP1 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)

Cat.No: TMPK-00680

Species: Cynomolgus,Rhesus

Expression System: HEK293 Cells

EpCAM/TROP1 Protein, Human, Recombinant (aa 24-265, His & Avi), Biotinylated

Cat.No: TMPK-00205

Species: Human

Expression System: HEK293 Cells

IL-25/IL17E Protein, Human, Recombinant (His)

Cat.No: TMPJ-00060

Species: Human

Expression System: HEK293 Cells

HSD17B11 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01303

Species: Human

Expression System: E. coli

ADAM8/CD156a Protein, Human, Recombinant (aa 17-655, His)

Cat.No: TMPK-00918

Species: Human

Expression System: HEK293 Cells

GPNMB Protein, Human, Recombinant (His)

Cat.No: TMPJ-01119

Species: Human

Expression System: HEK293 Cells

CRTAM Protein, Canine, Recombinant (His)

Cat.No: TMPK-01385

Species: Canine

Expression System: HEK293 Cells

CRTAM Protein, Mouse, Recombinant (His)

Cat.No: TMPK-00971

Species: Mouse

Expression System: HEK293 Cells

Thrombomodulin Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-00857

Species: Mouse

Expression System: HEK293 Cells

IBSP Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-00445

Species: Mouse

Expression System: HEK293 Cells

Rac1 Protein, Human, Recombinant (GST)

Cat.No: TMPY-01187

Species: Human

Expression System: Baculovirus Insect Cells

HLA-C*03:04&B2M&KRAS G12D (GADGVGKSAL) Monomer Protein, Human, MHC (His & Avi), Biotinylated

Cat.No: TMPK-01450

Species: Human

Expression System: HEK293 Cells

HLA-C 03:04&B2M&KRAS G12D (GADGVGKSAL) Monomer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01451

Species: Human

Expression System: HEK293 Cells

HLA-C*03:04&B2M&KRAS G12D (GADGVGKSAL) Tetramer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01456

Species: Human

Expression System: HEK293 Cells

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