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Piezo Channel

PIEZO1 is a mechanosensitive ion channel protein that in humans is encoded by the gene PIEZO1. PIEZO1 is expressed in the lungs, bladder and skin, where mechanosensation has important biological roles. Unlike PIEZO2 which is highly expressed in sensory dorsal root ganglia, PIEZO1 is not expressed in sensory neurons. Consequently, PIEZO1 plays a significant role in multiple neurobiological processes including axon regeneration, neural stem cells differentiation and neurological disease progression.

Cat. No.	Product Name	CAS No.	Purity
T37697L	D-GsMTx4 TFA 化合物 D-GsMTx4 TFA		98%
T37697L	D-GsMTx4 TFA 是一种具有选择性的蜘蛛毒液肽，是一种TRPC1 / 6和Piezo2抑制剂，可抑制属于 Piezo 和 TRP 通道家族的阳离子可渗透的机械敏感性通道（MSCs），阻断阳离子选择性的拉伸激活通道（SAC），减弱溶血磷脂酰胆碱（LPC）诱导的星形胶质细胞毒性和小胶质细胞反应性。D-GsMT...
T7506	Yoda 1 化合物Yoda 1	448947-81-7	99.98%
T7506	Yoda 1 是Piezo1激动剂，能够激活纯化的 Piezo1 通道。
TP1300	GsMTx4 TFA (1209500-46-8 free base) 化合物GsMTx4 TFA	TP1300	98.03%
TP1300	GsMTx4 TFA (1209500-46-8 free base) (GsMTx4 TFA) 是一种蜘蛛毒肽，可选择性地抑制属于 Piezo 和 TRP 通道家族的阳离子可渗透机械敏感通道 (MSC)。