toxin ii

AK-Toxin II is a host-specific toxin to Japanese white pear.

AM Toxin II is a Cyclic tetradepsipeptide isolated from Alternaria mali.

NaV1.5 channels blocker

AM Toxin III is a phytotoxic peptide.

Asebotoxin III is a diterpenoid obtained from the leaves of Asebi, Pieris japonica.

Grayanotoxins are a group of closely related neurotoxins named after Leucothoe grayana. Extract from leaves of Ericaceae.

Altertoxin III 是一种突变诱导剂，对鼠伤寒沙门氏菌 TA98、TA100 和 TA1537 具有致突变性。它能够从表现出致突变反应的A. alternata分离株提取物中通过Ames鼠伤寒沙门氏菌试验中发现。

Toxin IIc is a biochemical.

Grayanotoxins are a group of closely related neurotoxins named after Leucothoe grayana, a plant native to Japan originally. Extract from leaves Leucothoe grayana (Ericaceae).

Jingzhaotoxin-V是一种多肽，具有抑制作用，IC50值为604.2 nM，可显著抑制非洲爪蟾卵母细胞的钾电流。此外，Jingzhaotoxin-V对大鼠背根神经节神经元中的河豚毒素抗性钠电流和河豚毒素敏感钠电流也有抑制效果，其IC50值分别为27.6 nM和30.2 nM[1]。

Jingzhaotoxin-II是由32个氨基酸组成的神经毒素，包括两个酸性残基和两个碱性残基。该毒素能够抑制电压门控钠通道(VGSC)，并在心肌细胞上明显减缓TTX抗性(TTX-R) VGSC的快速失活，其IC50值为0.26μM。

Chloroquinoxaline sulfonamide (Chloroquinoxaline) 是拓扑异构酶 II alpha beta 毒物，具有抗肿瘤活性和免疫抑制特性，可抑制小鼠 B16 黑色素瘤细胞的增殖，可用于研究转移性结直肠癌。

BDS-II为含43个氨基酸的肽类毒素，作用为选择性抑制Kv3.4通道。

Trypacidin is a fungal metabolite originally isolated fromA. fumigatus.1It is active againstB. subtilisandM. bovis(MICs = 12.5 and 1.25 μg/ml, respectively), as well asT. cruziandT. gondii(MICs = 5-10 and 10-20 μg/ml, respectively).1,2It reduces viability and induces lysis of A549 human lung cancer cells (IC50s = 7.4 μM for both).3Trypacidin increases survival in a mouse model ofT. gondiiinfection when administered in six doses of 12.5 mg/kg each.1 1.Balan, J., Ebringer, L., Nemec, P., et al.Antiprotozoal antibiotics. II. Isolation and characterization of trypacidin, a new antibiotic, active against Trypanosoma cruzi and Toxoplasma gondiiJ. Antibiot. (Tokyo)16157-160(1963) 2.Song, Z., Liu, Y., Gao, J., et al.Antitubercular metabolites from the marine-derived fungus strain Aspergillus fumigatus MF029Nat. Prod. Res.1-8(2019) 3.Gauthier, T., Wang, X., Dos Santos, J.S., et al.Trypacidin, a spore-borne toxin from Aspergillus fumigatus, is cytotoxic to lung cellsPLoS One7(2)e29906(2012)

ATX-II TFA为源自海葵(Anemonia sulcata)毒素的特定Na+通道调节剂，能使细胞培养物对Na+、Halothane、Caffeine和Ryanodine敏感，并可诱发肺静脉心律失常和心房颤动。

GsAF-II，一种肽毒素，能电压依赖性阻断hERG1亚型钾通道，并对Nav1.x亚型钠离子通道展现阻断效应。

Retro-2 (2-{[(5-methyl-2-thienyl)methylene]amino}) 是一种植物毒素蓖麻毒素抑制剂，它保护 HeLa 细胞免受蓖麻毒素、Stx1 和 Stx2 的侵害，选择性地阻断早期内体蛋白质-高尔基体界面处的逆行毒素运输。

ATX-II为特定Na+通道调节剂，源自海葵(Anemonia sulcata)毒液。该化合物会使细胞培养物对Na+Halothane、Caffeine及Ryanodine敏感，并可诱发肺静脉心律失常及心房颤动。

β-Amanitin, a cyclic peptide toxin found in the poisonous Amanita phalloides mushroom, inhibits eukaryotic RNA polymerase II and III, thereby disrupting protein synthesis.

Aah II为一种从蝎Androctonus australis毒液中提取的钠通道调节剂。