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Search Results for " ubch "

Targets Recommended: Others

1

抑制剂 & 化合物

3

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T13242	UbcH5c-IN-1	Others	Others
	UbcH5c-IN-1 is a selective small-molecule Ubiquitin-conjugating enzyme UbcH5c inhibitor (Kd: 283 nM for E2 UbcH5c-IN-1 by covalent binding with Cys85).

化合物

Cat.No: T13242

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-02607	Ube2H Protein, Human, Recombinant UBC8,UBCH2,E2-20K,UBCH,ubiquitin-conjugati...	Human	E. coli
	UBE2H is a member of the ubiquitin-conjugating E2 family whose members perform the second step in the ubiquitination reaction. Initially identified as the main process for protein degradation, ubiquitination is believed nowadays to be crucial for a wider range of cellular processes. The outcome of the ubiquitin-conjugation reaction, and thereby the fate of the substrate, is heavily dependent on the number of ubiquitin molecules attached and how these ubiquitin molecules are inter-connected. To d...
TMPY-02842	UBE2L6 Protein, Human, Recombinant (His) UBCH8,ubiquitin-conjugating enzyme E2L 6,RIG-B	Human	E. coli
	UBCH8, also known as UBE2L6, belongs to the ubiquitin-conjugating enzyme family. The family of ubiquitin-conjugating (E2) enzymes is characterized by the presence of a highly conserved ubiquitin-conjugating (UBC) domain. These domains accommodate the ATP-activated ubiquitin (Ub) or ubiquitin-like (UBL) protein via a covalently linked thioester onto its active-site residue. E2 enzymes act via selective protein-protein interactions with the E1 and E3 enzymes and connect activation to covalent modi...
TMPY-02426	UBE2D1 Protein, Human, Recombinant (His) UBC4/5,E2(17)KB1,ubiquitin-conjugating enzyme E2D 1,UBCH...	Human	E. coli
	Ubiquitin-conjugating enzyme E2 D1 (UBE2D1), a member of human E2 ubiquitin-conjugating enzymes, is closely related to SFT, which is short for stimulator of iron (Fe) transport. In other words, UbcH5A is significantly up-regulated in the liver of iron-overloaded patients with hereditary hemochromatosis, as previously published for SFT. Moreover, a complex of UBE2D1 is critical in maintaining KRAS protein stability and propose that targeting such complex may be a unique strategy to degrade mutant...

重组蛋白

Ube2H Protein, Human, Recombinant

Cat.No: TMPY-02607

Species: Human

Expression System: E. coli

UBE2L6 Protein, Human, Recombinant (His)

Cat.No: TMPY-02842

Species: Human

Expression System: E. coli

UBE2D1 Protein, Human, Recombinant (His)

Cat.No: TMPY-02426

Species: Human

Expression System: E. coli

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