巯基

Bromobimane (Monobromobimane) 是一种非荧光物质，但与硫醇反应反应时生成荧光产物。Bromobimane 可被当作一种探针使用，常在临床医学上检验血液中硫化物的含量。

Fluorescein-5-maleimide (N-(5-Fluoresceinyl)maleimide) 是硫醇反应荧光染料 (λex=494 nm，λem=519 nm)，可用于将荧光素与蛋白质缀合。

TPE-MI (Tetraphenylethene maleimide) 是一种聚集诱导的发光原，可对活细胞进行染色，可用于捕捉露出的未折叠蛋白中的半胱氨酸，可检测双氢青蒿素研究疟疾寄生虫后的蛋白质损伤。

5-IAF 是吲哚乙酰胺的一种荧光素衍生物，是一种荧光探针，可用来标记蛋白质和其他含有游离硫醇（半胱氨酸侧链）。5-IAF 可标记狗肾脏Na,K-ATP 酶的催化（α）亚单位。

NBD-Cl (NBD chloride) 是非荧光剂，能够与巯基或氨基反应，产生高度荧光。

BODIPY-TS (also known as Thiol-green 2) is a highly efficient thiol-specific turn-on probe with a fast response. It incorporates a thiosulfonate scaffold as its thiol recognition unit. BODIPY-TS displays excellent selectivity, low detection limit, and quantitative reactivity towards thiols. Moreover, it exhibits low toxicity. Notably, BODIPY-TS exhibits excitation at 490 nm and emission at 515 nm.

NIR dye-1 is a near-infrared (NIR) fluorescent dye which has absorption and emission in the NIR region while retaining an optically tunable hydroxyl group.

SEluc-2, a bioluminescent probe derived from firefly luciferin, is designed for the sensitive and selective detection of thiols in living cells.

Acrylodan, when subjected to thiol reactions, exhibits sensitivity to the dipolarity and dynamics of its surrounding binding pocket, specifically those surrounding Cys 34.

6-Iodoacetamidofluorescein is a sulphhydryl-specific fluorescent dye utilized for selective labeling of -SH groups present in nuclear matrix polypeptides and proteins.

MTSEA-Fluorescein 是一种可用于离子通道研究的荧光探针。储存方式：避光。

Tetramethylrhodamine-5-iodoacetamide (5-TMRIA) is a thiol-selective reactive dye that is used to non-specifically label proteins via the cysteine residues and covalently label DNA fragments[1].