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抑制剂&激动剂
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TargetMol产品目录中 "ptu"的结果
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  • 抑制剂&激动剂
    24
    TargetMol | Inhibitors_Agonists
  • 重组蛋白
    3
    TargetMol | Recombinant_Protein
  • 多肽产品
    2
    TargetMol | Peptide_Products
  • 抗体抑制剂
    2
    TargetMol | Inhibitory_Antibodies
  • 天然产物
    6
    TargetMol | Natural_Products
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    1
    TargetMol | Antibody_Products
  • 分子与细胞研究
    1
    TargetMol | Inhibitors_Agonists
  • Propylthiouracil
    丙硫氧嘧啶, Pseudocapsaicin, NSC 70461, NSC 6498, 6-Propyl-2-thiouracil, 6-n-Propylthiouracil
    T130951-52-5
    Propylthiouracil (6-n-Propylthiouracil) 是一种甲状腺过氧化物酶抑制剂,也是一种5'-脱碘酶抑制剂。
    • ¥ 166
    In stock
    规格
    数量
  • Rosolutamide
    ASC-JM17, ALZ003, ALZ-003, ASC-JM-17
    T715521039760-91-2In house
    Rosolutamide (ALZ-003) 是一种姜黄素类似物,一种具有口服活性 Nrf1 和 Nrf2 激活剂。Rosolutamide 可调节氧化稳态,改善线粒体功能并促进自噬,减少突变蛋白聚集,并降低细胞内 线粒体活性氧 (ROS) 水平,可用于研究脊髓小脑性共济失调和亨廷顿病等神经退行性疾病。调节氧化稳态。
    • ¥ 1530
    In stock
    规格
    数量
  • D-Mannoheptulose
    D-甘露庚酮糖
    T109403615-44-9In house
    D-mannoheptose is the main non-structural carbohydrate in avocado. D-mannoheptose is a specific inhibitor of D-glucose phosphorylation. D-mannoheptose can prevent the release of insulin and the utilization of carbohydrates in rats.
    5日内发货
    询价
  • BPTU
    BMS-646786
    T4132870544-59-5
    BPTU (BMS-646786) 是一种非核苷酸类P2Y1受体变构拮抗剂,能够阻断位于胃肠道神经肌肉接头的 P2Y1受体,具有抗血栓活性。
    • ¥ 273
    In stock
    规格
    数量
  • PTUPB
    T125801287761-01-6
    PTUPB 是强效的sEH(IC50:0.9 μM)和COX-2(IC50:1.26 μM)的双向抑制剂。
    • ¥ 745
    In stock
    规格
    数量
  • D-Sedoheptulose 7-phosphate
    T192682646-35-7
    D-Sedoheptulose 7-phosphate is a common precursor of heptaic acid (group III) and the heptasaccharide of hygromycin B (group IV). This compound can be converted to NDP-heptose via similar biosynthetic pathways present in these substances.
    • 待询
    规格
    数量
  • Acetaminophen mercapturate
    T2021552372-86-8
    Paracetamol Mercapturate is a metabolite of Acetaminophen. It can also be used in the biological study of urinary antihypertensive drugs.
    • ¥ 10600
    4-6周
    规格
    数量
  • Clofibrate mercapturate
    T3097684489-15-6
    Clofibrate mercapturate is a urinary metabolite of clofibrate.
    • 待询
    规格
    数量
  • Paracetamol mercapturate
    T3388155748-93-1
    Paracetamol mercapturate is a deuterated metabolite of acetaminophen.
    • 待询
    规格
    数量
  • Pentachlorophenylmercapturic acid
    T3391268593-98-6
    Pentachlorophenylmercapturic acid is a bioactive chemical.
    • 待询
    规格
    数量
  • Pentylmercapturic acid
    T3392435985-42-3
    Pentylmercapturic acid is a bioactive chemical.
    • 待询
    规格
    数量
  • S-Allylmercapturic Acid
    N-Acetyl-S-allyl-L-cysteine, N-乙酰基-S-烯丙基-L-半胱氨酸, N-Acetyl-S-allylcysteine
    T3571023127-41-5
    S-Allylmercapturic Acid (N-Acetyl-S-allyl-L-cysteine) 是存在于黑蒜中的 S-allyl-L-cysteine 代谢物,具有潜在的抗痛风作用,抑制 CYP2D6 和 CYP 催化的反应。
    • ¥ 560
    35日内发货
    规格
    数量
  • 4-hydroxy Nonenal Mercapturic Acid
    T35971146764-24-1
    Peroxidation of common ω-6 polyunsaturated fatty acids (PUFAs) such as linoleic acid, DGLA, and arachidonic acid can give rise to 4-HNE. 4-HNE is cleared rapidly from the plasma and undergoes enterohepatic circulation as a glutathione conjugate in the rat. About two thirds of an administered dose of 4-HNE is excreted within 48 hours in the urine, primarily in the form of mercapturic acid conjugates. The C-1 aldehyde of 4-HNE is reduced to an alcohol in about half of these metabolites. The remainder are C-1 aldehydes or have been oxidized to C-1 carboxylic acids. These aldehydes and carboxylic acids can also form γ-lactols and γ-lactones, respectively, producing at least 4 or 5 end urinary metabolites of 4-HNE in vivo.
    • 待估
    35日内发货
    规格
    数量
  • Atrazine Mercapturate
    T36469138722-96-0
    Atrazine mercapturate is a major, glutathione-derived metabolite of atrazine , an herbicide that is effective in controlling a broad range of weeds. Atrazine has been reported to cause cancer in certain laboratory animals, have diverse effects on the reproductive system in animals and humans, and disrupt the normal function of the endocrine system. Atrazine mercapturate is readily measured in urine samples.
    • ¥ 5860
    35日内发货
    规格
    数量
  • D-Sedoheptulose-7-phosphate (barium salt)
    T3798917187-72-3
    D-Sedoheptulose-7-phosphate is an intermediate in the pentose phosphate pathway. [1] [2] In this pathway, transaldolase catalyzes the transfer of a three carbon dihydroxyacetone moiety from D-sedoheptulose-7-phosphate to glyceraldehyde-3-phosphate to generate D-fructose-6-phosphate . D-Sedoheptulose-7-phosphate is also an intermediate in carbon fixation in photosynthetic organisms, as well as in the biosynthesis of lipopolysaccharide, amino acids, secondary metabolites, and antibiotics. [3]
    • 待估
    35日内发货
    规格
    数量
  • S-Phenylmercapturic acid
    S-苯汞基酸, N-Acetyl-S-phenyl-L-cysteine
    T739404775-80-8
    S-Phenylmercapturic acid是苯的一种代谢物,可用作苯暴露的生物标志物。
    • ¥ 137
    In stock
    规格
    数量
  • Naptumomab
    T817041412892-09-1
    Naptumomab是一种针对肿瘤细胞的超级抗原(TTS)融合蛋白。它能激活免疫系统,使之识别并消灭肿瘤细胞。该化合物主要应用于肾细胞癌等难治性实体肿瘤的研究领域。
    • ¥ 2490
    2-4周
    规格
    数量
  • Naptumomab estafenatox
    ANYARA, ABR-217620
    T9901A-045676258-98-3
    Naptumomab estafenatox (ABR-217620) 是肿瘤靶向超抗原 (TTS),它是一种融合蛋白,由抗5T4抗体和SEA E-120超抗原组成。Naptumomab estafenatox 可用于肺癌的研究。
    • 待询
    待询
    规格
    数量
  • Sedoheptulose anhydride
    TN7007469-90-9
    Sedoheptulose anhydride is a natural product.
    • ¥ 10890
    待询
    规格
    数量
  • D-altrofurano-heptulose-3
    D-阿卓-呋喃庚酮糖, alpha-D-Altro-3-heptulofuranose
    TN708025545-06-6
    D-altrofurano-heptulose-3 (alpha-D-Altro-3-heptulofuranose) 从猕猴桃 (Rupr. & Maxim.) Maxim., 猕猴桃科的根茎中分离得到。
    • ¥ 1300
    待询
    规格
    数量
  • Methyl (methyl 3-deoxy-D-arabino-heptulopyranosid)onate-7-phosphate
    TXB-0021891382-80-8
    Methyl (methyl 3-deoxy-D-arabino-heptulopyranosid)onate-7-phosphate 是用于糖生物学研究的生化试剂。糖生物学研究糖的结构、合成、生物学及进化,涵盖碳水化合物化学、聚糖酶学、蛋白质与聚糖的识别,以及聚糖在生物系统中的功能。该领域与基础研究、生物医学和生物技术密切相关。
    • 待询
    5日内发货
    规格
    数量
  • CCB02
    T107042100864-57-9In house
    CCB02 是选择性的 CPAP-tubulin 相互作用抑制剂。CCB02能够与 tubulin 结合,竞争 β-tubulin 的 CPAP 结合位点,IC50 值为 689 nM,显示出高效的抗肿瘤活性。CCB02 对其他的蛋白没有抑制作用,包括中心体、细胞周期相关蛋白,对 Aurora A,Plk1,Plk2,CDK2 和 CHK1 的磷酸化状态也无作用。
    • ¥ 1290 TargetMol
    In stock
    规格
    数量
  • Perseitol
    甘露庚糖醇
    T9297527-06-0
    Perseitol 是一种产生于成熟的鳄梨植物的化合物。它能够转变为 D-甘露庚酮糖,可提供能量以及运输碳水。
    • ¥ 320
    In stock
    规格
    数量
  • 3,4-Dehydro-L-proline
    T660294043-88-3
    The leguminous shrub,Leucaena leucocephala(Leucaena) is wide‐spread in tropical and subtropical agricultural systems and provides a ready source of protein for livestock. However, the presence of mimosine, a non‐protein, amino acid comprising about 12% of the dry matter in growing tips ofLeucaena, is toxic to animals. Mimosine is degraded rapidly in the rumen to produce 3,4‐dihydroxypyridine (3,4‐DHP) and 2,3‐dihydroxypyridine (2,3‐DHP), both of which remain toxic to animals[1]. 3,4-DHP, as a derivative of the plant amino acid mimosine, is goitrogenic in cattle, sheep, and mice. In contrast to established antithyroid compounds, such as methimazole (MMI) and propylthiouracil (PTU), 3,4-DHP has no SH-group. 3,4-DHP with various concentrations inhibited incorporation of125I into protein in human thyroid slices. It also suppressed the activation of lymphocytes by PHA (phytohaemagglutinin) and PWM (pokeweed mitogen). Suppression with 3,4-DHP was seen at 100 and 1000 μmol L (P< 0.001 vs both PHA and PWM). Those, together with a very low murine bone marrow toxicity, probably related to the absence of an SH-group, make 3,4-DHP a potential antithyroid drug[2].
    • ¥ 1133
    5日内发货
    规格
    数量
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