nana

Sialic acid aldolase (Pm NaNa) (EC 4.1.3.3) 是一种I型醛缩酶，可催化N-乙酰神经氨酸 (Neu5Ac) 的可逆裂解，生成丙酮酸和N-乙酰-D-甘露糖胺 (ManNAc)，而且反应平衡倾向于Neu5Ac的裂解。

N-Acetylneuraminic acid (Acide aceneuramique) 是一种九碳唾液酸单糖，通常存在于细胞膜上的糖蛋白和哺乳动物细胞中的神经节苷脂等糖脂中。它可用于神经传递、白细胞外渗、病毒或细菌感染以及碳水化合物-蛋白质识别。

N-Acetylneuraminic acid (Standard)是N-Acetylneuraminic acid的标准品，适用于定量分析、质量控制及生化实验等相关研究。N-Acetylneuraminic acid是一种天然的九碳唾液酸单糖，可用于神经传递、白细胞外渗、病毒或细菌感染以及碳水化合物-蛋白质识别。

Nonanal 是木材腐烂真菌的生长因子。 Nonanal 是松梢甲虫的潜在引诱剂。

Nanaomycin A 是一种醌类抗生素，可重新激活人类癌细胞中沉默的肿瘤抑制基因。 Nanaomycin A 是 DNMT3B 的特异性抑制剂 (IC50 = 500 nM)。

Nanatinostat (CHR-3996)是一种具有口服利用度的HDAC抑制剂，对HDAC1/2/3的IC50=3~7 nM，对其他亚型的IC50则＞200nM，还能够抑制肿瘤细胞增殖和诱导凋亡，可用于研究神经退行性疾病和癌症。

(Rac)-Nanatinostat ((Rac)-CHR-3996, example 44) 是一种高效的HDAC抑制剂，IC50低于330 nM。它表现出抗癌特性，有效抑制HeLa、U937和HUT细胞的生长。

2-Norbornanamine, 2,3-dimethyl- is a Drug / Therapeutic Agent.

2-Norbornanamine, 2-ethyl-N-methyl- is a Drug / Therapeutic Agent.

2-Norbornanamine, N,2,3-trimethyl- is a Drug / Therapeutic Agent.

2-Norbornanamine, N,2-dimethyl- is a Drug / Therapeutic Agent.

2-Norbornanamine, N,3,3-trimethyl- is a Drug / Therapeutic Agent.

2-Norbornanamine, N,N,2,3-tetramethyl- is a Drug / Therapeutic Agent.

Nanangenine B is a drimane sesquiterpene that has been found inAspergillus.1It is active againstB. subtilis(IC50= 62 μg/ml) and cytotoxic to NS-1 mouse myeloma cells (IC50= 38 μg/ml). 1.Lacey, H.J., Gilchrist, C.L.M., Crombie, A., et al.Nanangenines: Drimane sesquiterpenoids as the dominant metabolite cohort of a novel Australian fungus, Aspergillus nanangensisBeilstein J. Org. Chem.152631-2643(2019)

Nanangenine F is a drimane sesquiterpene fungal metabolite that has been found inA. nanangensis.1It is active againstB. subtilis(IC50= 78 μg/ml) and cytotoxic to NS-1, DU145, and MCF-7 cancer and NFF non-cancerous cells (IC50s = 49, 95, 49, and 84 μg/ml, respectively). 1.Lacey, H.J., Gilchrist, C.L.M., Crombie, A., et al.Nanangenines: Drimane sesquiterpenoids as the dominant metabolite cohort of a novel Australian fungus, Aspergillus nanangensisBeilstein J. Org. Chem.152631-2643(2019)

Nanangenine G is a drimane sesquiterpene that has been found inAspergillus.1It is cytotoxic to NS-1 mouse myeloma cells (IC50= 47 μg/ml). 1.Lacey, H.J., Gilchrist, C.L.M., Crombie, A., et al.Nanangenines: Drimane sesquiterpenoids as the dominant metabolite cohort of a novel Australian fungus, Aspergillus nanangensisBeilstein J. Org. Chem.152631-2643(2019)

Nanatinostat, also known as Tractinostat, CHR-3996 and VRx-3996, is an orally bioavailable, second-generation hydroxamic acid-based inhibitor of histone deacetylase (HDAC) with potential antineoplastic activity. HDAC inhibitor CHR-3996 inhibits HDAC, resulting in an accumulation of highly acetylated histones, the induction of chromatin remodeling, and the selective transcription of tumor suppressor genes; these events may result in the inhibition of tumor cell division and the induction of tumor cell apoptosis. This agent may upregulate HSP70 and downregulate anti-apoptotic Bcl-2 proteins more substantially than some first-generation HDAC inhibitors. HDACs, upregulated in many tumor cell types, are a family of metalloenzymes responsible for the deacetylation of chromatin histone proteins.

Isonanangenine B is a drimane sesquiterpene lactone that has been found in Aspergillus. It decreases survivin mRNA expression in a reporter assay when used at concentrations of 13.6, 18.42, and 26.31 µM. Isonanagenine B (18.42 µM) inhibits STAT3 and NF-κB binding to the survivin promoter in chromatin immunoprecipitation (ChIP) assays. It also induces apoptosis in COLO 320DM cells.

Nonanal (Standard) 是 Nonanal 的标准品，适用于定量分析、质量控制及生化实验等相关研究。Nonanal 是木材腐烂真菌的生长因子。 Nonanal 是松梢甲虫的潜在引诱剂。

Nanaomycin D 是一种抗生素，具有优异的抗菌活性。

Nanaomycin B 是一种抗生素，具有对革兰氏阳性菌、分枝杆菌、支原体和真菌的活性。

Nanaomycin E 是一种抗生素，具有对革兰氏阳性细菌和真菌的活性。

Nanangenine H是一种二萜类化合物，存在于曲霉菌中。

Nanangenine D 是一种存在于曲霉菌中的二萜化合物。