亚甲蓝(Basic Blue 9)水合物,作为鸟苷酸环化酶(sGC)、单胺氧化酶A(MAO-A)及NO合酶(NOS)的抑制剂,常用于医疗作为血管加压剂及染料。该化合物通过影响一氧化氮合成酶 鸟苷酸环化酶信号通路,能够减少脉冲前抑制,同时作为一种氧化还原循环化合物,具有穿透血脑屏障的能力,并作为Tau蛋白聚集的抑制剂,有助于缓解脑水肿、减轻小胶质细胞活化和神经炎症。
Levine Eosin-MethyleneBlue Agar Medium (Levine EMB Agar) 是一种用于分离肠道病原体的弱选择性培养基,特别适用于大肠杆菌。每升该培养基包含以下成分:10.0 g 蛋白胨,10.0 g 乳糖,2.0 g 磷酸氢二钾,15.0 g 琼脂,0.4 g 伊红,0.065 g 亚甲蓝。
Hydromethylthionine, also known as LMTM and LeucomethyleneBlue, is a apotent tau aggregation inhibitor for the treatment of Alzheimer's disease (AD) and frontotemporal dementia. Hydromethylthionine showed pharmacological activity on brain structure and function as both monotherapy and as an add-on to symptomatic treatment in certain patients with Alzheimer’s disease.