glycoprotein d

Linarin (Acacetin-7-O-rutinoside) 是一种选择性的乙酰胆碱酯酶 (AChE) 抑制剂，从薄荷花提取物中分离得到。

Norverapamil hydrochloride (D591 hydrochloride) 是 Verapamil 的 N-去甲基代谢物，是 L 型钙通道阻滞剂和 P-糖蛋白 (P-gp) 功能抑制剂。

3,4,6-Tri-O-benzyl-D-galactal 是一种用于糖生物学研究的生化试剂。糖生物学研究包括糖的结构、合成、生物学和进化，涉及碳水化合物化学、聚糖的形成与降解酶学、蛋白质与聚糖的识别及聚糖在生物系统中的功能。此领域与基础研究、生物医学和生物技术紧密联系。

MS-073 (CP-162398) is a P-glycoprotein inhibitor (P-gp). The in vitro resistance to vincristine (VCR) was almost completely reversed in VCR-resistant P388 cells, and the resistance of VCR, adriamycin (ADM), etoposide, and actinomycin D in ADM-resistant hu

Milbemycin A4 oxime is a derivative of milbemycin A4 and a component of milbemycin oxime , compounds that both have insecticidal and nematocidal activity. Milbemycin A4 oxime (0.05 mg kg) reduces the number of microfilariae of the heartworm D. immitis in naturally infested dogs. It inhibits the growth of clinical isolates of C. glabrata with MIC80 values ranging from 16 to greater than 32 μg ml. Milbemycin A4 oxime (2.5 μg ml) blocks efflux of fluconazole from a clinical isolate of C. glabrata, but not from a strain lacking the efflux pumps CgCDR1 and PDH1, and reduces the MICs of fluconazole and 4-nitroquinoline 1-oxide in wild-type C. glabrata. It enhances adriamycin-induced inhibition of cell growth, as well as increases the intracellular accumulation of adriamycin and the P-glycoprotein substrate rhodamine 123 , in adriamycin-resistant, but not -sensitive, MCF-7 breast cancer cells in a concentration-dependent manner.

Sialic acids, commonly present as terminal carbohydrates on glycoconjugates, are essential for a variety of cellular functions including cell adhesion and signal recognition, as well as the formation and progression of tumors. 3-Deoxy-D-glycero-D-galacto-2-nonulosonic acid is a deaminated sialic acid that was first identified at the nonreducing ends of oligosialyl chains in rainbow trout egg glycoprotein.[1] It is thought to be a precursor for the biosynthesis of other members of the sialic acid family.[2] 3-Deoxy-D-glycero-D-galacto-2-nonulosonic acid can be used to analyze nonulosonic acid residues in polysialoglycoproteins.[1]

Defensin HNP-3 is a peptide secreted by human polymorphonuclear leukocytes (PMNs) that has antimicrobial properties. It induces lysis of mammalian cells when used at a concentration of 25 μg mL. It also inhibits growth of E. faecalis (ED50 = 100 nM) and clinical isolates of P. aeruginosa (MIC90 = 4 μM). HNP-3 binds to recombinant HIV-1 envelope glycoprotein (gp120) and human CD4 (Kds = 52.8 and 34.9 nM, respectively). It also binds to recombinant, immobilized human surfactant protein D (SP-D; Kd = 55.7 nM) and inhibits focus formation in Madin-Darby canine kidney (MDCK) cells infected with influenza A virus (IAV).

Peniterphenyl A，一种源于深海青霉属植物的天然产物，能够抑制HSV-1 2病毒的细胞内入侵。它可能通过与HSV-1 2病毒的糖蛋白D直接相互作用，干扰病毒的吸附和膜融合过程，进而有效阻断病毒感染。因此，Peniterphenyl A是抗HSV-1 2研究领域中一个极具潜力的先导化合物。

Ceefourin 1 是一种具有高度选择性的多药抗性蛋白 4 (MRP4) 抑制剂。它能够抑制多种 MRP4 底物的转运，但对其他 ABC 转运蛋白无影响。它是苯并噻唑，常作为高危神经母细胞瘤的化学增敏剂。

Fusion Inhibitory Peptide (Z-D-Phe-Phe-Gly-OH, FIP, Virus Replication Inhibitory Peptide) 通过抑制病毒糖蛋白的膜融合活性，有效阻断病毒复制。

Hypophyllanthin 是珠子草中的一种木脂素，能直接抑制 P-gp 的活性，具有很强的抗炎活性。

Human vitamin D-binding protein (hDBP) is an abundant, multifunctional, and highly polymorphic serum glycoprotein synthesized by the liver1.

Phenylmethyl 2-(acetylamino)-2-deoxy-3-O-methyl-α-D-glucopyranoside 是一种生化试剂，用于糖生物学研究。糖生物学主要研究糖类的结构、合成、生物学功能及其进化过程，涵盖碳水化合物化学、聚糖的合成与降解酶学、蛋白质与聚糖的识别及其在生物系统中的作用。此领域与基础研究、生物医学和生物技术密切相关。