antioxidant;antiviral

Dodecyl gallate 是一种抗氧化剂，普遍用作食品制造及制药和化妆品行业中。它还对动物病毒，如非洲猪瘟病毒 (ASFV)具有作用活性。

Luteolin (Luteolol) 属于黄酮类天然产物，是一种 Nrf2 抑制剂、PDE 抑制剂。Luteolin 具有多种生物活性，包括抗肿瘤、抗氧化、抗炎、抗菌、抗病毒、抗过敏和促凝血等。

Kaempferol (Robigenin) 属于天然类黄酮，是一种 ERRα 和 ERRγ 的反向激动剂。Kaempferol 具有抗肿瘤、抗炎、抗氧化、抗菌和抗病毒等多种活性。

Chrysin (5,7-Dihydroxyflavone) 是一种雌激素阻断剂。

Arctigenin ((-)-Arctigenin) 是一种存在于牛蒡中的木脂素，具有抗氧化、抗肿瘤、抗炎和抗病毒活性。它可研究代谢紊乱和中枢神经系统功能障碍。

Octyl gallate (Octyl 3,4,5-trihydroxybenzoate) 具有抗菌、抗氧化作用，有选择性和敏感性的荧光特性，广泛用作食品添加剂。它对 HSV-1，水泡性口炎病毒和脊髓灰质炎病毒有显著的抗病毒作用。

Arbidol (Umifenovir) 是一种具有口服活性广谱抗病毒化合物，属于融合抑制剂，可与 SARS-CoV-2 刺突蛋白相互作用。Arbidol 对多种冠状病毒显示出抑制活性。Arbidol 具有抗炎抗氧化活性，可用于研究浓度感染。

Bilberry Extract 是一种越橘提取物,具有抗菌、抗炎癌、抗病毒和抗氧化活性，可用于研究食品着色。

Isomangiferin 是一种天然产物，具有抗病毒的作用。它还具有抗氧化和自由基清除活性。

Cynarin (1,5-Dicaffeoylquinic acid) 是一种抗窒息剂，具有抗氧化、抗组胺和抗病毒等多种生物活性。

Theaflavin 是在红茶中发现的一种多酚类黄酮，具有如抗氧化、抗癌、抗炎和抗病毒多种生物活性。

Chrysoeriol 是一种天然黄酮，可从热带植物Coronopus didymus 中提取获得，具有强大的抗氧化功能，能够抑制脂质的过氧化。

Haemanthamine is an alkaloid isolated from the Amaryllidaceae plants with potent anticancer activity. It inhibits protein biosynthesis during the elongation stage of translation. It has antimalarial, pro-apoptotic, antiviral, antioxidant, and anticonvulsa

Haemanthamine hydrochloride is an alkaloid isolated from the Amaryllidaceae plants with potent anticancer activity. It inhibits protein biosynthesis during the elongation stage of translation. It has antimalarial, pro-apoptotic, antiviral, antioxidant, an

D609 (Tricyclodecan-9-yl-Xanthogenate) 具有广泛的生物活性，包括抗氧化、抗凋亡、抗胆碱能、抗肿瘤、抗炎、抗病毒、抗增殖和神经保护活性。D609 通过引起磷脂酰胆碱 (PC) 特异性磷脂酶 C (PC-PLC) 和鞘磷脂合酶 (SMS) 的竞争性抑制来发挥作用。

3-Hydroxyterphenyllin is a p-terphenyl fungal metabolite originally isolated from A. candidus that has diverse biological activities, including antioxidant, antiproliferative, antibacterial, and antiviral properties.1,2,3,4 It has a 96% scavenging effect on 2,2-diphenyl-1-picrylhydrazyl radicals when used at a concentration of 100 μg/ml.2 3-Hydroxyterphenyllin inhibits the growth of HeLa cervical, A549 lung, and HepG2 liver cancer cells (IC50s = 23, 36, and 32 μM, respectively), as well as methicillin-resistant S. aureus (MRSA) and V. vulnificus bacteria (MIC = 31 μg/ml for both).3 It also inhibits HIV-1 integrase in both coupled and strand transfer assays (IC50s = 2.8 and 12.1 μM, respectively).4References1. Kurobane, I., Vining, L.C., McInnes, A.G., et al. 3-Hydroxyterphenyllin, a new metabolite of Aspergillus candidus. Structure elucidation by 1H and 13C nuclear magnetic resonance spectroscopy. J. Antibiot. (Tokyo) 32(6), 559-564 (1979).2. Yen, G.-C., Chang, Y.-C., Sheu, F., et al. Isolation and characterization of antioxidant compounds from Aspergillus candidus broth filtrate. J. Agric. Food Chem. 49(3), 1426-1431 (2001).3. Wang, W., Liao, Y., Tang, C., et al. Cytotoxic and antibacterial compounds from the coral-derived fungus Aspergillus tritici SP2-8-1. Mar. Drugs 15(11), E348 (2017).4. Singh, S.B., Jayasuriya, H., Dewey, R., et al. Isolation, structure, and HIV-1-integrase inhibitory activity of structurally diverse fungal metabolites. J. Ind. Microbiol. Biotechnol. 30(12), 721-731 (2003). 3-Hydroxyterphenyllin is a p-terphenyl fungal metabolite originally isolated from A. candidus that has diverse biological activities, including antioxidant, antiproliferative, antibacterial, and antiviral properties.1,2,3,4 It has a 96% scavenging effect on 2,2-diphenyl-1-picrylhydrazyl radicals when used at a concentration of 100 μg/ml.2 3-Hydroxyterphenyllin inhibits the growth of HeLa cervical, A549 lung, and HepG2 liver cancer cells (IC50s = 23, 36, and 32 μM, respectively), as well as methicillin-resistant S. aureus (MRSA) and V. vulnificus bacteria (MIC = 31 μg/ml for both).3 It also inhibits HIV-1 integrase in both coupled and strand transfer assays (IC50s = 2.8 and 12.1 μM, respectively).4 References1. Kurobane, I., Vining, L.C., McInnes, A.G., et al. 3-Hydroxyterphenyllin, a new metabolite of Aspergillus candidus. Structure elucidation by 1H and 13C nuclear magnetic resonance spectroscopy. J. Antibiot. (Tokyo) 32(6), 559-564 (1979).2. Yen, G.-C., Chang, Y.-C., Sheu, F., et al. Isolation and characterization of antioxidant compounds from Aspergillus candidus broth filtrate. J. Agric. Food Chem. 49(3), 1426-1431 (2001).3. Wang, W., Liao, Y., Tang, C., et al. Cytotoxic and antibacterial compounds from the coral-derived fungus Aspergillus tritici SP2-8-1. Mar. Drugs 15(11), E348 (2017).4. Singh, S.B., Jayasuriya, H., Dewey, R., et al. Isolation, structure, and HIV-1-integrase inhibitory activity of structurally diverse fungal metabolites. J. Ind. Microbiol. Biotechnol. 30(12), 721-731 (2003).

Methyl 3,4-dihydroxyphenylacetate is a polyphenol that has been found inI. aquifoliumseeds and has antioxidant and antiviral activities.1,2It scavenges 2,2-diphenyl-1-picrylhydrazyl radicals in a cell-free assay (IC50= 0.0025 mg ml).1Methyl 3,4-dihydroxyphenylacetate (0.01 μg ml) inhibits enterovirus 71 replication in rhabdomyosarcoma cells.2 1.Nahar, L., Russell, W.R., Middleton, M., et al.Antioxidant phenylacetic acid derivatives from the seeds of Ilex aquifoliumActa Pharm.55(2)187-193(2005) 2.Wang, L., Wang, J., Wang, L., et al.Anti-enterovirus 71 agents of natural productsMolecules20(9)16320-16333(2015)

(2S)-Isoxanthohumol 是一种由啤酒花原异戊烯基二氢黄酮 Isoxanthohumol 的微生物转化代谢物。

Hispolon 是一种多酚。Hispolon 可以从林芝Phellinus linteus 中分离出来。Hispolon 具有抗癌、抗糖尿病、抗病毒、保肝、抗氧化和抗炎活性。

Lobaric acid is a depsidone metabolite that has been isolated from Stereocaulon lichen species with antioxidant, antiproliferative, antiviral, and enzyme inhibitory activites. It scavenges superoxide radicals in a cell-free assay (IC50 = 97.9 μmol) and inhibits proliferation in a panel of leukemia, colorectal, gastric, breast, ovarian, prostate, pancreatic, and lung cancer cell lines (EC50s = 15.2-63.9 μg ml). Lobaric acid inhibits protein tyrosine phosphatase 1B (PTP1B; IC50 = 0.87 μM for the human recombinant enzyme) and production of 12(S)-HETE (Item No. 34570) by 12(S)-lipoxygenase (IC50 = 28.5 μM). In vivo, lobaric acid (250 μM) decreases lesion number, but not lesion diameter, in tobacco leaves infected with tobacco mosaic virus (TMV).

Haemanthamine hydrochloride 是从Amaryllidaceae 植物中分离出来的一种蛇毒碱样生物碱，具有强大的抗癌活性。Haemanthamine hydrochloride 靶向核糖体以在翻译的延长阶段抑制蛋白质的生物合成。Haemanthamine hydrochloride 具有促凋亡，抗氧化剂，抗病毒，抗疟疾和抗惊厥活性。

Antioxidant agent-9 是一种肽，序列是Asp-Trp。Antioxidant agent-9 具有抗氧化活性。Antioxidant agent-9 也是一种潜在的SARS-CoV-2抗病毒剂，其亲和力强度与 Chloroquine 和 Favipiravir 相当。

Cyanidin 3-sambubioside chloride (Cyanidin-3-O-sambubioside chloride) 是一种从植物中提取的花青素，是一种 NO和 H274Y 突变的抑制剂，对流感神经氨酸酶具有抑制作用。Cyanidin 3-sambubioside chloride 具有抗氧化，抗血管生成和抗病毒活性，抑制血管紧张素转换酶 (ACE) 的活性，可用于研究病毒感染和心血管疾病。

Chrysophanein (Chrysophanol 1-O-glucoside) 是来自芦荟 (Aloe hijazensis) 叶和根的羟醌化合物，具有抗菌、抗真菌和抗氧化活性，MIC 值为8-256 μg mL。Chrysophanein 可用于研究真菌感染。