T3965

Fevipiprant (NVP-QAW039) 是一种选择性、强效、可逆的竞争性 CRTh2 拮抗剂，KD 值为1.1 nM，IC50为0.44 nM，能够引发人体嗜酸性粒细胞的形状变化。

Afimetoran (BMS-986256) 是一种有效的toll 样受体拮抗剂，在炎症和自身免疫性疾病中有研究的价值。

(S,R,S)-AHPC-C5-NH2, also known as VH032-C5-NH2, is a synthetic compound designed as an E3 ligase ligand-linker conjugate. This compound combines the VH032-based von Hippel-Lindau (VHL) ligand with a linker, enabling it to function as a PROTAC degrader for estrogen-related receptor α (ERRα).

Zetomipzomib maleate (KZR-616), a novel immunoproteasome inhibitor, effectively and selectively inhibits the LMP7 subunit (hLMP7/mLMP7 IC50: 39/57 nM) and LMP2 subunit (hLMP7/mLMP7 IC50: 131/179 nM) of the immunoproteasome. This compound shows promising potential for research in various autoimmune diseases.

Arg-Gly-Asp-Cys TFA serves as the binding motif through which fibronectin interacts with cell adhesion molecules. This compound has the ability to hinder platelet aggregation and fibrinogen binding.

Cyanazine 是一种三嗪类除草剂，广泛用于防除多种禾本科与阔叶杂草。研究表明，Cyanazine 不具遗传毒性，且在农业应用中具有高选择性与高效性，是除草机制及环境毒理学研究中重要的模型化合物。

RMC-4630 (SHP2-IN-7) 是 SHP2 的抑制剂。

(S,R,S)-AHPC-CO-C9-acid is a ligand-linker conjugate specifically designed to function as an E3 ligase ligand. This compound possesses the capability to be attached to a ligand, which enables the formation of PROTACs with proteins.