首页 工具
登录
购物车

搜索结果

Search Results for " duloxetine "
Targets Recommended: Serotonin Transporter

8

抑制剂 & 化合物

5

同位素标记化合物

如果没找到您满意的产品或者您对产品有其他要求,可以联系我们专业顾问为您提供针对性的合理建议。     QQ咨询       网站留言咨询

提交您的定制咨询

点击图片重新获取验证码
Cat. No. Product Name Target Signaling Pathways
T7061 Duloxetine

Serotonin Transporter Neuroscience
Duloxetine 是一种 5 羟色胺-去甲肾上腺素重吸收 (serotonin-norepinephrine reuptake) 抑制剂,Ki=4.6 nM,可作用于广泛性焦虑症的研究。
T1471 Duloxetine hydrochloride

Duloxetine HCl,盐酸度洛西汀,LY-248686 hydrochloride,(S)-Duloxetine hydrochloride,LY-248686 HCl

Dopamine Receptor; 5-HT Receptor; Serotonin Transporter; Norepinephrine GPCR/G Protein; Neuroscience
Duloxetine hydrochloride ((S)-Duloxetine hydrochloride) 是一种 5-羟色胺-去甲肾上腺素重吸收 (serotonin-norepinephrine reuptake) 抑制剂 (SNRI),Ki=4.6 nM,可用于广泛性焦虑症的研究。
T11114 Duloxetine metabolite Para-Naphthol Duloxetine

度洛西汀代谢物,Para-Naphthol duloxetine

Others Others
Para-Naphthol Duloxetine is a serotonin-norepinephrine reuptake inhibitor (SNRI),is a metabolite of Duloxetine.
T37211 5-hydroxy-6-methoxy (S)-Duloxetine

Others Others
5-hydroxy-6-methoxy (S)-Duloxetine is a metabolite of (S)-duloxetine . It is formed from (S)-duloxetine via a 5- or 6-hydroxy duloxetine intermediate, which is formed by the cytochrome P450 (CYP) isoforms CYP1A2 and CYP2D6, and a catechol duloxetine intermediate. 5-hydroxy-6-methoxy (S)-Duloxetine binds to the serotonin (5-HT), norepinephrine, and dopamine transporters with Ki values of 266, 920, and 2,814 nM, respectively.
T13790 N-Methyl Duloxetine hydrochloride

Others Others
N-Methyl Duloxetine hydrochloride elicits both tonic and use-dependent block of neuronal Na+ channels. N-Methyl Duloxetine hydrochloride is an analgesic.
T61008 (±)-Duloxetine hydrochloride

Others Others
(±)-Duloxetine ((Rac)-Duloxetine) hydrochloride 是 Duloxetine hydrochloride 的外消旋物。Duloxetine hydrochloride 可用于研究糖尿病性神经性疼痛、纤维肌痛和重度抑郁症,它是 5-羟色胺去甲肾上腺素再摄取的抑制剂。
T68386 (R)-Duloxetine Hydrochloride

Others Others
(R)-Duloxetine Hydrochloride is a napthalenyloxy-substituted amine used in binding studies of human serum albumin along with (S)-Duloxetine. Unlike its enantiomer, it is not a very effective dual serotonin and norepinephrine reuptake inhibitor (SNRI).
T83888 (S)-5-hydroxy-6-methoxy Duloxetine maleate

Others Others
(S)-5-羟基-6-甲氧基Duloxetine是(S)-duloxetine的一个活性代谢物,主要通过对血清素(5-HT)和去甲肾上腺素的再摄取进行抑制。它通过(S)-duloxetine经过一个5-或6-羟基Duloxetine中间体以及一个儿茶酚Duloxetine中间体形成,这些中间体由细胞色素P450 (CYP)同型酶CYP1A2和CYP2D6形成。(S)-5-羟基-6-甲氧基Duloxetine在脂质膜中抑制5-HT转运体(SERT)、去甲肾上腺素转运体(NET)和多巴胺转运体(DAT),其对人类转运体的抑制常数(Kis)分别为266、920和2,814 nM。

化合物

Duloxetine
Cat.No: T7061
Synonym:
Target: Serotonin Transporter
Duloxetine hydrochloride
Cat.No: T1471
Synonym: Duloxetine HCl,盐酸度洛西汀,LY-248686 hydrochloride,(S)-Duloxetine hydrochloride,LY-248686 HCl
Target: Dopamine Receptor, 5-HT Receptor, Serotonin Transporter, Norepinephrine
Duloxetine metabolite Para-Naphthol Duloxetine
Cat.No: T11114
Synonym: 度洛西汀代谢物,Para-Naphthol duloxetine
Target: Others
5-hydroxy-6-methoxy (S)-Duloxetine
Cat.No: T37211
Synonym:
Target: Others
N-Methyl Duloxetine hydrochloride
Cat.No: T13790
Synonym:
Target: Others
(±)-Duloxetine hydrochloride
Cat.No: T61008
Synonym:
Target: Others
(R)-Duloxetine Hydrochloride
Cat.No: T68386
Synonym:
Target: Others
(S)-5-hydroxy-6-methoxy Duloxetine maleate
Cat.No: T83888
Synonym:
Target: Others
Cat. No. Product Name Target Signaling Pathways
T11113 Duloxetine D3 hydrochloride

(S)-Duloxetine D3 hydrochloride,LY248686 D3 hydrochloride

Others Others
Duloxetine D3 hydrochloride is a serotonin-norepinephrine reuptake inhibitor (SNRI) with a Ki of 4.6 nM, used for treatment of major depressive disorder and generalized anxiety disorder (GAD).Duloxetine D3 hydrochloride ((S)-Duloxetine D3 hydrochloride) i
TMIH-0478 rac-Duloxetine-d3

rac-Duloxetine-d3 是 rac-Duloxetine 的氘代化合物。rac-Duloxetine 的 CAS 号为 116817-13-1。
TMIH-0205 Duloxetine-d3 HCl

Duloxetine-d3 HCl 是 Duloxetine HCl 的氘代化合物。Duloxetine HCl 的 CAS 号为 136434-34-9。Duloxetine hydrochloride 是一种 5-羟色胺-去甲肾上腺素重吸收 (serotonin-norepinephrine reuptake) 抑制剂 (SNRI),Ki=4.6 nM,可用于广泛性焦虑症的研究。
TMIJ-0300 Duloxetine-d7

Duloxetine-d7 是 Duloxetine 的氘代化合物。Duloxetine 的 CAS 号为 116539-59-4。Duloxetine 是一种 5 羟色胺-去甲肾上腺素重吸收 (serotonin-norepinephrine reuptake) 抑制剂,Ki=4.6 nM,可作用于广泛性焦虑症的研究。
TMIJ-0325 Duloxetine-d7 Maleate

Duloxetine-d7 Maleate 是 Duloxetine Maleate 的氘代化合物。Duloxetine Maleate 的 CAS 号为 116817-86-8。

同位素标记化合物

Duloxetine D3 hydrochloride
Cat.No: T11113
Synonym: (S)-Duloxetine D3 hydrochloride,LY248686 D3 hydrochloride
Target: Others
rac-Duloxetine-d3
Cat.No: TMIH-0478
Synonym:
Target:
Duloxetine-d3 HCl
Cat.No: TMIH-0205
Synonym:
Target:
Duloxetine-d7
Cat.No: TMIJ-0300
Synonym:
Target:
Duloxetine-d7 Maleate
Cat.No: TMIJ-0325
Synonym:
Target:
联系我们
400-820-0310

上海市静安区江场三路238号8楼