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Search Results for " cipram "
Targets Recommended: 5-HT Receptor

4

抑制剂 & 化合物

1

天然产物

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Cat. No. Product Name Target Signaling Pathways
T20828 Citalopram

Cipram,Lu 10-171,Lu-10-171 Lu10-171

5-HT Receptor GPCR/G Protein; Neuroscience
Citalopram (Lu 10-171) 是一种具有口服活性的、选择性的血清素再摄取抑制剂 (SSRI),是一种选择性5-羟色胺再摄取抑制剂,是一种 S(+)-对映体 (Escitalopram) 和 R(-)-对映体的外消旋混合物。Citalopram 具有抗抑郁活性,可增强血清素能神经传递,可用于研究老年痴呆。
T6493L (R)-Citalopram oxalate

Others Others
(R)-Citalopram oxalate is a less active enantiomer of Escitalopram Oxalate. Escitalopram Oxalate is a potent and selective serotonin reuptake inhibitor.
T69943 Citalopram oxalate

Others Others
Citalopram oxalate is a furancarbonitrile that is one of the SEROTONIN UPTAKE INHIBITORS used as an antidepressant. The drug is also effective in reducing ethanol uptake in alcoholics and is used in depressed patients who also suffer from tardive dyskinesia in preference to tricyclic antidepressants, which aggravate this condition.
T1483 Citalopram hydrobromide

Lu 10-171,Nitalapram HBr,Bonitrile HBr,XU-62-320,Lu 10-171 HBr,氢溴酸西酞普兰,Citalopram HBr

5-HT Receptor; Serotonin Transporter; Autophagy Autophagy; GPCR/G Protein; Neuroscience
Citalopram hydrobromide (XU-62-320) 是一种选择性 5-羟色胺再摄取抑制剂,可选择性地抑制 CNS 神经元对 5-羟色胺的再摄取,从而增强中枢神经系统中的 5-羟色胺能活性,也具有抗抑郁活性。它抑制兔血小板中 5-HT 的摄取,IC50为 14 nM。

化合物

Citalopram
Cat.No: T20828
Synonym: Cipram,Lu 10-171,Lu-10-171 Lu10-171
Target: 5-HT Receptor
(R)-Citalopram oxalate
Cat.No: T6493L
Synonym:
Target: Others
Citalopram oxalate
Cat.No: T69943
Synonym:
Target: Others
Citalopram hydrobromide
Cat.No: T1483
Synonym: Lu 10-171,Nitalapram HBr,Bonitrile HBr,XU-62-320,Lu 10-171 HBr,氢溴酸西酞普兰,Citalopram HBr
Target: 5-HT Receptor, Serotonin Transporter, Autophagy
Cat. No. Product Name Target Signaling Pathways
T0185 Escitalopram

Seroplex,依他普仑,S-(+)-Citalopram,艾司西酞普兰,(S)-Citalopram

Dopamine Receptor; 5-HT Receptor; Serotonin Transporter; Adrenergic Receptor; AChR; Norepinephrine; Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Escitalopram (Seroplex) 是一种外消旋 Citalopram 的 S-对映体,是一种选择性 5-羟色胺再摄取抑制剂,Ki=0.89 nM,比 R(-)-enantiomer 结合亲和力高 30 倍。它对多巴胺转运体和去甲肾上腺素转运体均有选择性,是一种研究抑郁症的抗抑郁药。

天然产物

Escitalopram
Cat.No: T0185
Synonym: Seroplex,依他普仑,S-(+)-Citalopram,艾司西酞普兰,(S)-Citalopram
Target: Dopamine Receptor, 5-HT Receptor, Serotonin Transporter, Adrenergic Receptor, AChR, Norepinephrine, Histamine Receptor
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