win

WIN site inhibitor 1 is a WIN site of chromatin-associated WD repeat-containing protein 5 (WDR5) inhibitor (Kd: 0.1 nM), with anti-cancer activity.

WIN 51,708 是一种神经激肽受体（NK1）拮抗剂。

WIN 54954 是一种可口服的抗病毒剂，抑制柯萨奇病毒，抑制病毒翻译或转录。WIN 54954 可用于研究小核糖核酸病毒感染。

WIN 55,212-2 Mesylate ((R)-(+)-WIN 55212) 是 cannabinoid receptor 激动剂，对人重组 CB1 受体(Ki:62.3 nM) 和 CB2 受体 (Ki:3.3 nM)。

WIN 68577 是一种天然化合物，可作为天然产物对照品，其 CAS 号为 151928-33-5。

WIN-64821 是一种天然化合物，可作为天然产物对照品，其 CAS 号为 150881-27-9。

Win-62005 is an inhibitor of cyclic AMP phosphodiesterase III (PDE III)(Kis: 25 and 26 nM for rat heart and canine aorta).

Win 58237 is an inhibitor of cyclic nucleotide phosphodiesterase (PDE) (Ki: 170 nM for PDE V), with vasorelaxant activity.

WIN site inhibitor 1 TFA is a WIN site of chromatin-associated WD repeat-containing protein 5 (WDR5) inhibitor (Kd: 0.1 nM).

WIN 62577 是一种具物种选择性的速激肽NK1受体拮抗剂，同时也作为一种变构增强剂，对M3受体展现微摩尔效力。此外，WIN 62577 针对SARS-CoV-2表现出强效的抗病毒活性。

Win 45164 是一种口服活性糖皮质激素受体 (Glucocorticoid Receptor) 配体，能够抑制垂体 - 肾上腺轴。此化合物促进去除肾上腺的雄性大鼠的肝脏糖原储存和胸腺溶解，并展现抗炎特性。Win 45164 可用于研究炎症和神经系统疾病。

WIN 5063-3 is the enantiomeric analog of the antimicrobial Thiamphenicol.

WIN 62,577 is a allosteric antagonist of mAChR.

WIN-68056 is a wetting agent in x-ray contrast compositions.

(±)-WIN 55,212-2 is a potent aminoalkylindole cannabinoid (CB) receptor agonist with a Ki value of 62.3 and 3.3 nM for human recombinant central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors, respectively. In contrast, the enantiomer (-)-WIN 55,212-3 acts a partial inverse agonist at CB1 (pIC50 = 5.5) and as a competitive neutral antagonist of CB2, reversing the inverse agonism evoked by SR 144528 (pEC50 = 5.3). (+)-WIN 55,212 (mesylate) is a mixture of the two enantiomers, (+)-WIN 55,212-2 and (-)-WIN 55,212-3.

WIN 66306 is a cyclic heptapeptide antagonist of neurokinin-1 (NK1) and NK2 receptors originally isolated from A. flavipes. It binds to NK1 and NK2 receptors and inhibits contractions induced by substance P in isolated guinea pig ileum in a concentration-dependent manner.

(-)-WIN 55,212-3 mesylate 是 WIN 55,212-2 mesylate的低活性对映异构体，无神经保护活性和减少肠道运输的作用。(-)-WIN 55,212-3 mesylate是一种大麻素受体激动剂， 可用于研究神经系统疾病。

Win 18446 是口服有效的睾丸特异性的ALDH1a2的抑制剂，IC50为 0.3 μM。Win 18446 抑制睾丸内视黄醇合成视黄酸，可逆的抑制多个物种的精子形成，。

Topterone（Win 17,665） 是一种有效的局部抗雄激素，抑制睾酮和二氢睾酮对阉割未成熟雄性仓鼠腰部器官发育的刺激。

Epostane通过抑制 3β-羟类固醇脱氢酶，阻止孕酮与孕烯醇酮的生物合成，从而起到抗孕激素和终止妊娠的作用。[4]

Milrinone (Win 47203) 是一种 PDE3抑制剂，也是一种强心药、血管舒张药。

Hycanthone (Etrenol(mesylate)) 是 Lucanthone 的生物活性代谢产物，是一种抗血吸虫病药。它是一个噻吨酮类 DNA 嵌入剂，可抑制 RNA 合成以及 DNA 拓扑异构酶 I 和 II。它通过直接蛋白质结合来抑制核酸生物合成并抑制嘌呤内切核酸酶1，KD 为 10 nM。

Amifloxacin (Win49375) 是有效的喹诺酮类抗菌剂。

Disoxaril (BRN 3626820, WIN 51711) is an anti-picornavirus agent that inhibits enterovirus replication by binding to a hydrophobic bag within the VP1 coat protein, thereby stabilizing virions and preventing their uncoating. When used in combination with A