sarizotan2hcl

Sarizotan 2HCl 是一种 hERG 通道抑制剂和 5-羟色胺5-HT1A受体激动剂，具有潜在的抗抑郁作用，可用于研究帕金森运动障碍。

Sarizotan HCl (EMD 128130 HCl) 是一种 hERG 通道抑制剂和 5-羟色胺5-HT1A受体激动剂，具有潜在的抗抑郁作用，可用于研究帕金森运动障碍

Sarizotan (EMD 128130) is an orally active compound that acts as an agonist for serotonin 5-HT 1A receptors and dopamine receptors. It has shown potent activity with IC 50 values of 6.5 nM for rat 5-HT 1A , 0.1 nM for human 5-HT 1A , 15.1 nM for rat D 2 , 17 nM for human D 2 , 6.8 nM for human D 3 , and 2.4 nM for human D 4.2 .