protozoal

Diclazuril (R-64433) 是一种具有口服活性的抗球虫剂，是苯乙腈衍生物。它可用于某些传染病和寄生虫病的相关研究。

Nimorazole (Nimorazol) 是一种 2-硝基咪唑，是一种低氧细胞辐射敏化剂。它具有抗感染，抗滴虫等原生动物的作用。它有头颈癌的研究潜力。

Primaquine diphosphate 是一种合成的 8-氨基喹啉衍生物，具有抗疟特性。它是一种能破坏间日疟原虫和卵形疟原虫肝脏晚期和潜在组织形态的化合物。

Diloxanide furoate (Dichlofurazol) 是一种具有口服活性的抗原生动物化合物，可用于研究组织内阿米巴和其他一些原生动物感染。

DNA crosslinker 6 (compound 1) 作为一种抗动质体化学物质，展现了与AT-DNA高效结合的特性，并且能有效阻断AT-hook 1与DNA的结合，其IC50值仅为0.03 µM。此化合物还显示出对T. brucei的显著抗原虫活性，其EC50达到0.83 µM。

Quinacrine is a compound that is commonly used as an anti-protozoal agent. It inhibits voltage-dependent sodium channels (IC50: 3.3 μM) and suppresses aldehyde oxidase (IC50: 3.3 μM). Quinacrine prevents misfolding of prion protein (EC50: 0.3 μM). As an e

Diloxanide (RD3803) 是一种抗原虫制剂，可研究组织学内阿米巴原虫或者其他原虫感染引起的无症状肠道阿米巴病。它是一种活性的鲁米那抗阿米巴试剂，是由其前药二氯尼特糠酸酯在胃肠道中水解得来的。

Quinacrine is a compound with multiple actions that is commonly used as an anti-protozoal agent. It has also been shown to be a highly potent autophagy inhibitor, although the dose required to achieve this effect is considerably cytotoxic (LD50 = 2.5 μM). Quinacrine analog 34 is a derivative of quinacrine that was designed with an improved cell viability profile (LD50 = 27 μM) to inhibit autophagy. At a minimum concentration of 0.5 μM, this compound has been shown to increase the protein levels of the autophagy biomarker LC3-II and to induce lysosome deacidification.

Hydroxymetronidazole (Metronidazole-OH) is a nitroimidazole compound that functions as a metabolite of Metronidazole. It is commonly employed in poultry research to investigate bacterial and protozoal diseases, as well as in the study of swine dysentery and genital trichomoniasis in cattle.

Teclozan 是一种苄胺衍生物类的抗原虫剂。Teclozan 在肠腔中表现出抗 G. intestinalis 作用，能够干预磷脂代谢，阻止花生四烯酸的形成。Teclozan 能够用于研究原生动物感染。

Pinafide is a rodenticide and anti-protozoal agent. Pinafide shows strong cytostatic activity against both HeLa and KB cells and is moderately toxic to both mice and rats. It has been proved active against experimental tumors and shown to be inhibitor of two DNA viruses. Pinafide blocks cell growth by inhibiting DNA and RNA synthesis. It has been shown to bind to double-helical DNA by intercalation. Pinafide inhibited the activity of M. tuberculosis NAD⁺-dependent DNA ligase A at concentrations of 50 uM. At the chemical screening was found that pinafide inhibited B-Myb transcriptional activity in luciferase assays. The cross placental-barrier studies showed that 3H-pinafide was present in the 14-day fetuses.

Xenopsin precursor fragment 为抗菌肽，展现抗菌 抗真菌(MIC: 10-500 μg mL)及抗原虫(MIC: 2-20 μg mL)效能。

Hydroxy Metronidazole-d4 是 Hydroxy Metronidazole 的氘代化合物。Hydroxy Metronidazole 的 CAS 号为 4812-40-2。Hydroxymetronidazole (Metronidazole OH) 是一种硝基咪唑化合物，作为甲硝唑的代谢产物。Hydroxymetronidazole 通常用于家禽研究，以研究细菌和原生动物疾病，以及研究猪痢疾和牛生殖器滴虫病。

Chlorophorin shows high anti-protozoal activity with an MIC of 0.25 microg ml. Chlorophorin can strongly inhibit mushroom tyrosinase activity with IC50 values of 2.5 ± 0.408 uM; it inhibits α-melanocyte-stimulating hormone-induced melanin production in B16F10 melanoma cells.