protac linker-22

NH2-C2-NH-Boc (PROTAC Linker 22) 是一种属于 alkyl chain 类的 PROTAC linker，可用于 PROTAC 分子的合成。

2-Bromo-22-dimethyl-acetamido-PEG3-acid is a polyethylene glycol (PEG) derivative commonly employed as a PEG-based PROTAC linker during PROTAC synthesis[1].

Pomalidomide-PEG4-C2-NH2 (E3 Ligase Ligand-Linker Conjugates 22) 是一种合成的 E3 连接酶配体- linker 偶联物，用于 PROTAC 技术中。

Pomalidomide-amido-PEG3-C2-NH2, known as Cereblon Ligand-Linker Conjugates 22, is a synthesized E3 ligase ligand-linker conjugate designed for use in PROTAC technology. It consists of the Pomalidomide-based cereblon ligand and a 3-unit PEG linker. [1]

4-Boc-amino-22-dimethylbutyric acid is an alkyl ether-derived PROTAC linker, suitable for the synthesis of PROTACs.

Thalidomide-NH-C6-NH-Boc is a synthesized E3 ligase ligand-linker conjugate containing the cereblon ligand derived from Thalidomide and a linker utilized in the synthesis of MI-389 (compound 22). MI-389 is a highly effective phthalimide PROTAC degrader developed from the multi-targeted receptor tyrosine kinase inhibitor sunitinib.

HO-CONH-C3-PEG3-NH2 为一种连接子,应用于PROTAC降解剂22-SLF的合成中.

(S,R,S)-AHPC-Ac-CO-cyclohexene-Bpin 属于 E3 泛素酶配体+连接子偶联物 (E3 Ligase Ligand-Linker Conjugates) 类型的化合物。该化合物主要应用于合成 PROTAC SMARCA2 4-degrader-22。