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TargetMol产品目录中 "

pai 2

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  • 抑制剂&激动剂
    2
    TargetMol | Inhibitors_Agonists
  • 重组蛋白
    3
    TargetMol | Recombinant_Protein
  • 同位素
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    TargetMol | Isotope_Products
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    TargetMol | Antibody_Products
  • Aflatoxin G1-13C17
    Aflatoxin G1-13C17
    T355201217444-07-9
    Aflatoxin G1-13C17is intended for use as an internal standard for the quantification of aflatoxin G1by GC- or LC-MS. Aflatoxin G1is a mycotoxin that has been found inA. terricola.1In vivo, aflatoxin G1is lethal to ducklings (LD50= 1.18 mg kg).2It induces hepatocellular carcinoma tumor formation and lethality in rats when administered at doses of 1.4 and 3 mg animal, respectively. Aflatoxin G1also inhibits liver and kidney succinate dehydrogenase and fumarase, as well as kidney cytochrome oxidase, NADH oxidase, α-glycerophosphate dehydrogenase, isocitrate dehydrogenase, and malate dehydrogenase in rats.3 1.Moubasher, A.H., el-Kady, I.A., and Shoriet, A.Toxigenic Aspergilli isolated from different sources in EgyptAnn. Nutr. Aliment.31(4-6)607-615(1977) 2.Wogan, G.N., Edwards, G.S., and Newberne, P.M.Structure-activity relationships in toxicity and carcinogenicity of aflatoxins and analogsCancer Res.31(12)1936-1942(1971) 3.Bai, N.J., Pai, M.R., and Venkitasubramanian, T.A.Mitochondrial function in aflatoxin toxicityIndian J. Biochem. Biophys.14(4)347-349(1977)
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  • TM5441 sodium
    T848912319722-53-5
    TM5441是一种口服生物可利用的PAI-1(纤溶酶原激活物抑制剂-1)抑制剂,其对多种癌症细胞系的IC50值介于13.9到51.1μM之间,能诱导人类癌症细胞的内在凋亡(apoptosis)。此外,TM5441还可减轻Nω-硝基-1-精氨酸甲酯引发的心脏高血压和血管老化。
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    8-10周
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