nsaids

Tolfenamic Acid (GEA 6414) 是一种非甾体抗炎剂和抗癌剂，可用于治疗偏头痛的症状。它能选择性地抑制COX-2的活性，在 LPS 诱导的犬 DH82 单核细胞/巨噬细胞中，对COX-2的IC50值为 13.49 μM(3.53 μg/mL)。

S-(+)-Ketoprofen ((S)-(+)-Ketoprofen) 抑制 COX-1和 COX-2的IC50值分别为 1.9 和 27 nM。

Felbinac (Dapson) 是非甾体抗炎药，可用于肌肉炎症和关节炎的研究。

Fenamic acid (N-Phenylanthranilic acid) 是氯通道阻滞剂。

L-Glutamic acid monosodium salt monohydrate （MSG monohydrate）是一种重要的食品添加剂，具有胃肠道保护作用，在营养代谢、能量需求、免疫响应、氧化应激、信号通路调节及突触传递中有重要作用。L-Glutamic acid monosodium salt monohydrate 诱导小鼠肝脏和脑组织氧化应激、DNA损伤和细胞凋亡。L-Glutamic acid monosodium salt monohydrate 可通过多种机制保护非甾体抗炎药及幽门螺杆菌引起的胃肠道损伤。

Aspirin Aluminum is an intermolecular compound that can inhibit gastrointestinal mucosal disorders induced by NSAIDs.

β-Glucuronidase-IN-3 (Compound 49) 是一种β-glucuronidase的共价变构抑制剂。它对大肠杆菌 β-葡萄糖醛酸酶 (EcGUS) 显示出强效的抑制能力 (IC50: 12.9 nM)。这种作用是通过可逆共价修饰EcGUS的半胱氨酸残基 (Cys28、Cys443和Cys197) 实现的。β-Glucuronidase-IN-3 可应用于研究肠道微生物相关的疾病，尤其在减轻Irinotecan和非甾体抗炎药 (NSAIDs) 的毒性副作用方面。

Metazin belongs to nonsteroidal anti-inflammatory drugs (NSAIDs). It works by reducing hormones that cause pain and inflammation in the body.

Difenpiramide 是一种非甾体抗炎药 (NSAID)，用于退行性及炎症性关节病的研究。研究显示，Difenpiramide 的抗炎效果与吲哚美辛及苯丁酸相当，并具有外周镇痛、解热及尿酸排泄促进作用。Difenpiramide 抑制前列腺素及炎症介质合成，同时不影响血小板聚集或凝血，其治疗指数优于参比 NSAID。

O-Desmethyl-N-deschlorobenzoyl indomethacin is a metabolite of the non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor indomethacin .1It is formed from indomethacin in isolated rabbit hepatocytes. O-Desmethyl-N-deschlorobenzoyl indomethacin (600 μM) decreases the viability of HL-60 leukemia cells when cultured with glucose oxidase.2It has also been used in the synthesis of prostaglandin D2receptor antagonists.3 1.Evans, M.A., Papazafiratou, C., Bhat, R., et al.Indomethacin metabolism in isolated neonatal and fetal rabbit hepatocytesPediatr. Res.15(11)1406-1410(1981) 2.Morgan, A.G.M., Babu, D., Michail, K., et al.An evaluation of myeloperoxidase-mediated bio-activation of NSAIDs in promyelocytic leukemia (HL-60) cells for potential cytotoxic selectivityToxicol. Lett.28048-56(2017) 3.Torisu, K., Kobayashi, K., Iwahashi, M., et al.Discovery of new chemical leads for prostaglandin D2 receptor antagonistsBioorg. Med. Chem. Lett.14(17)4557-4562(2004)

Diclofenac deanol is a nonsteroidal anti-inflammatory drug (NSAID) of the phenylacetic acid class with anti-inflammatory, analgesic, and antipyretic properties. Contrary to the action of many traditional NSAIDs, diclofenac inhibits cyclooxygenase (COX)-2 enzyme with greater potency than it does COX-1.

AK-106, also known as AK106-001616, is a selective inhibitor of cytosolic phospholipase A2 (cPLA2) inhibitor. AK-106 has been shown to have analgesic activites similar to non-steroidal anti-inflammatory drugs (NSAIDs).

WAY-313201是一种生化研究中使用的活性分子。

1,3-Distearoyl glycerol, a diacylglycerol with stearic acid at the sn-1 and sn-3 positions, is present in wheat bran extract. It is utilized in creating prodrug versions of NSAIDs (ibuprofen, naproxen, and diclofenac) with decreased ulcerogenicity.

Carboxymethyl-β-cyclodextrin, 99% 是一种阳离子环糊精，常用作药物载体，并且能够高效且具有选择性地结合非甾体抗炎药 （NSAID）。

(S)-Ketoprofen-d3 是 (S)-Ketoprofen 的氘代化合物。(S)-Ketoprofen 的 CAS 号为 22161-81-5。S-(+)-Ketoprofen 抑制COX-1和COX-2的IC50值分别为 1.9 和 27 nM。

Tolfenamic acid (Standard) 是 Tolfenamic acid 的标准品，适用于定量分析、质量控制及生化实验等相关研究。Tolfenamic Acid (GEA 6414) 是一种非甾体抗炎剂和抗癌剂，可用于治疗偏头痛的症状。它能选择性地抑制COX-2的活性，在 LPS 诱导的犬 DH82 单核细胞/巨噬细胞中，对COX-2的IC50值为 13.49 μM(3.53 μg/mL)。