首页工具

登录

搜索结果

Search Results for " legumain "

Targets Recommended: Gamma-secretase

6

抑制剂 & 化合物

9

重组蛋白

如果没找到您满意的产品或者您对产品有其他要求，可以联系我们专业顾问为您提供针对性的合理建议。 QQ咨询网站留言咨询

Cat. No.	Product Name	Target	Signaling Pathways
T39905	Legumain inhibitor 1	Gamma-secretase	Neuroscience; Proteases/Proteasome; Stem Cells
	Legumain inhibitor 1 是一种具有高效性和特异性的 Legumain 抑制剂，具有潜在的抗癌活性，可用于研究癌症。
T20626	Esomeprazole	Proton pump; Cysteine Protease	Membrane transporter/Ion channel; Proteases/Proteasome
	Esomeprazole 是奥美拉唑(omeprazole) 的S-异构体，抑制溶酶体半胱氨酸蛋白酶legumain，防止癌症转移。它是一种质子泵抑制剂（PPI）。
T12769	RR-11a	Others	Others
	RR-11a is a synthetic enzyme Legumain inhibitor.
T38984	Z-Ala-Ala-Asn-AMC Cbz-Ala-Ala-Asn-AMC,Z-Ala-Ala-Asn-AMC
	Z-Ala-Ala-Asn-AMC, also known as Cbz-Ala-Ala-Asn-AMC, serves as a substrate for legumain. The overexpression of legumain in 293 HEK-Leg cells results in efficient cleavage of Cbz-Ala-Ala-Asn-AMC.
T81945	LE 28
	LE 28是一款选择性且活性依赖的legumain探针，其荧光仅在与活性legumain结合时产生。该化合物适用于癌症和炎症性疾病研究领域。
T36903	Rasagiline-13C3 (mesylate) Rasagiline-13C3 (mesylate)
	Rasagiline-13C3is intended for use as an internal standard for the quantification of rasagiline by GC- or LC-MS. Rasagiline is an inhibitor of monoamine oxidase B (MAO-B; IC50= 4.43 nM for the rat brain enzyme).1It is selective for MAO-B over MAO-A (IC50= 412 nM for the rat brain enzyme). It inhibits serum and NGF withdrawal-induced apoptosis of PC12 cells when used at concentrations ranging from 0.01 to 100 μM.2Rasagiline inhibits rat brain MAO-Bin vivo(ED50= 0.1 mg/kg).1It reduces cerebral ede...

化合物

Legumain inhibitor 1

Cat.No: T39905

Target: Gamma-secretase

Cat.No: T20626

Target: Proton pump, Cysteine Protease

Cat.No: T12769

Target: Others

Z-Ala-Ala-Asn-AMC

Cat.No: T38984

Synonym: Cbz-Ala-Ala-Asn-AMC,Z-Ala-Ala-Asn-AMC

Cat.No: T81945

Rasagiline-13C3 (mesylate)

Cat.No: T36903

Synonym: Rasagiline-13C3 (mesylate)

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-00876	Legumain Protein, Mouse, Recombinant (His) AI746452,AEP,AU022324,Prsc1,legumain	Mouse	HEK293 Cells
	Legumain Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 49.8 kDa and the accession number is A2RTI3.
TMPY-02873	Legumain Protein, Sus scrofa (Pig), Recombinant (His) legumain	Sus scrofa (Pig)	HEK293 Cells
	Legumain Protein, Sus scrofa (Pig), Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 49.7 kDa and the accession number is A0A287AW67.
TMPY-06640	Legumain Protein, Human, Recombinant (His) PRSC1,AEP,legumain,LGMN1	Human	HEK293 Cells
	Legumain Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 49.12 kDa and the accession number is Q99538.
TMPK-01146	LGMN Protein, Human, Recombinant (His) AI746452,Legumain,LGMN1,Prsc1,AEP,LGMN,AU022324	Human	HEK293 Cells
	Recently, functional studies have demonstrated that legumain (LGMN) cleaves both amyloid β-protein precursor and tau, promoting senile plaques and formation of neurofibrillary tangles, which may play a crucial role in the pathogenesis of Alzheimer's disease (AD). In single-variant association analysis, none of the common variants in LGMN were statistically significant. In gene-based analysis, the LGMN gene also showed no association with AD.
TMPH-02431	Legumain Protein, Cynomolgus, Recombinant (His & Myc)	Cynomolgus	Baculovirus Insect Cells
	Has a strict specificity for hydrolysis of asparaginyl bonds. Can also cleave aspartyl bonds slowly, especially under acidic conditions. Required for normal lysosomal protein degradation in renal proximal tubules. Required for normal degradation of internalized EGFR. Plays a role in the regulation of cell proliferation via its role in EGFR degradation. May be involved in the processing of proteins for MHC class II antigen presentation in the lysosomal/endosomal system. Legumain Protein, Cynomolg...
TMPH-02432	Legumain Protein, Cynomolgus, Recombinant (E. coli, His & Myc)	Cynomolgus	E. coli
	Has a strict specificity for hydrolysis of asparaginyl bonds. Can also cleave aspartyl bonds slowly, especially under acidic conditions. Required for normal lysosomal protein degradation in renal proximal tubules. Required for normal degradation of internalized EGFR. Plays a role in the regulation of cell proliferation via its role in EGFR degradation. May be involved in the processing of proteins for MHC class II antigen presentation in the lysosomal/endosomal system. Legumain Protein, Cynomolg...
TMPY-00729	Cystatin D Protein, Human, Recombinant (His) CST5,MGC71922,cystatin D	Human	HEK293 Cells
	Cystatins are natural inhibitors of papain-like (family C1) and legumain-related (family C13) cysteine peptidases. The mammalian cystatin superfamily members are of three major types, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. As a member of type 2 cystatin, cystatin D is a single-domain protein and also has cysteine residues that form disulfide bridges. In contrast with the wider distribution of all the other family 2 cystatins, cystatin D is tissue-restricte...
TMPY-02077	Cystatin A Protein, Human, Recombinant (His) STFA,STF1,cystatin A,AREI	Human	E. coli
	Cystatin-A, also known as Cystatin-AS, Stefin-A and CSTA, is a cytoplasm protein which belongs to thecystatin family. Cystatin-A / CSTA is a cysteine proteinase inhibitor with a molecular mass of 11 kDa, and is located mainly in the keratohyaline granules of the stratum granulosum and the cornified envelope of the stratum corneum in the epidermis. The cystatins are a family of cysteine protease inhibitors with homology to chicken cystatin. Cystatins are physiological inhibitors of cystein...
TMPY-02090	Cystatin B Protein, Human, Recombinant (His) PME,EPM1A,STFB,ULD,cystatin B (stefin B),EPM1,CST6	Human	E. coli
	Cystatin-B, also known as CPI-B, Liver thiol proteinase inhibitor, Stefin-B, CSTB and CST6, is a cytoplasm and nucleus protein which belongs to thecystatin family. Cystatin-B / CSTB is an intracellular thiol proteinase inhibitor. Tightly binding reversible inhibitor of cathepsins L, H and B. Cystatin-B / CSTB is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. Cystatin-B / CSTB is also thought to play a role in protecting against the prot...

重组蛋白

Legumain Protein, Mouse, Recombinant (His)

Cat.No: TMPY-00876

Species: Mouse

Expression System: HEK293 Cells

Legumain Protein, Sus scrofa (Pig), Recombinant (His)

Cat.No: TMPY-02873

Species: Sus scrofa (Pig)

Expression System: HEK293 Cells

Legumain Protein, Human, Recombinant (His)

Cat.No: TMPY-06640

Species: Human

Expression System: HEK293 Cells

LGMN Protein, Human, Recombinant (His)

Cat.No: TMPK-01146

Species: Human

Expression System: HEK293 Cells

Legumain Protein, Cynomolgus, Recombinant (His & Myc)

Cat.No: TMPH-02431

Species: Cynomolgus

Expression System: Baculovirus Insect Cells

Legumain Protein, Cynomolgus, Recombinant (E. coli, His & Myc)

Cat.No: TMPH-02432

Species: Cynomolgus

Expression System: E. coli

Cystatin D Protein, Human, Recombinant (His)

Cat.No: TMPY-00729

Species: Human

Expression System: HEK293 Cells

Cystatin A Protein, Human, Recombinant (His)

Cat.No: TMPY-02077

Species: Human

Expression System: E. coli

Cystatin B Protein, Human, Recombinant (His)

Cat.No: TMPY-02090

Species: Human

Expression System: E. coli

我们的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

Copyright © 2015-2024 TargetMol Chemicals Inc. All rights reserved. 沪ICP备20019793号-4

沪公网安备 31010602006700号

沪公网安备 31010602006700号

TargetMol Loading

联系我们

电话：

400-820-0310

邮箱：

service@tsbiochem.com

QQ：

2881945090（终端用户）

2885109491（经销商）

经销：

终端：

地址：

上海市静安区江场三路238号8楼