hydrocortisone

Hydrocortisone (Cortisol) 是一种糖皮质激素，由肾上腺素皮质分泌。Hydrocortisone 激动糖皮质激素受体，可促进蛋白质分解代谢、糖异生、毛细血管壁稳定性、肾脏钙排泄，并抑制免疫和炎症反应。

Hydrocortisone hemisuccinate (hydrocortisone 21-hemisuccinate*free acid) 是糖皮质激素， 是口服有活性的甾体抗炎剂。它能够降低IL-6(IC50:6.7 μM)、IL-3(IC50:21.4 μM)的生物活性，可用于研究溃疡性结肠炎。

Hydrocortisone 17-butyrate (Cortisol 17-butyrate) 是一种肾上腺皮质激素类药物。

Hydrocortisone aceponate (Hydrocortisone 17-propionate 21-acetate) 是一种有效的外用糖皮质激素，以乳膏的形式用于治疗各种皮肤病。

Hydrocortisone sodium succinate is a glucocorticoid which is used to alleviate allergic reactions, particularly those of the skin and gums.

Hydrocortisone buteprate (Hydrocortisone probutate) is a medium potent, non-halogenated double-ester of hydrocortisone with a favorable benefit risk ratio for the treatment of inflammatory skin disorders.

Hydrocortisone phosphate (sodium) (Hydrocortisone 21-phosphate (sodium)) 是一种具有较弱抗炎作用的软类固醇，作用时间短，能够用于研究几种眼部疾病和胃溃疡。

Hydrocortisone hemisuccinate hydrate (Hydrocortisone 21-hemisuccinate hydrate) 是一种具有口服活性的糖皮质激素甾体抗炎药物（SAID）。该化合物在抑制IL-6和IL-3的生物活性方面表现出效果，其IC50值分别为6.7 μM和21.4 μM。可用于进行溃疡性结肠炎（UC）的相关研究。

Hydrocortisone Valerate (Westcort) 具有抗炎、止痒和血管收缩的特性。

Hydrocortisone cypionate is a corticosteroid ester and synthetic glucocorticoid corticosteroid.

Hydrocortisone-21-lysinate is a hydrocortisone prodrug that is water soluble.

Acyclovir mixture with hydrocortisone is used for Herpes simplex labialis.

Hydrocortisone phosphate is the pharmaceutical term for cortisol, which is a steroid hormone, in the glucocorticoid class of hormones, increases blood sugar through gluconeogenesis, to suppress the immune system, and to aid in the metabolism of fat, protein, and carbohydrate.

Hydrocortisone-d4 是 Hydrocortisone 的氘代化合物。Hydrocortisone 的 CAS 号为 50-23-7。Hydrocortisone 是肾上腺皮质分泌的糖皮质激素。

Hydrocortisone acetate (Cortisol 21-acetate) 是皮质类固醇，能够减少轻微皮肤刺激或痔疮引起的肿胀、搔痒和疼痛。

Tetrahydrocortisone是cortisone的无活性代谢物，是cortisone参与应激反应并被酶还原的产物，可以作为皮质醇代谢的指标。

5β-Dihydrocortisone is a sterol metabolite of cortisone by 5β-reductase (AKR1D1) in liver.

5β-Dihydrocortisone is a sterol metabolite of cortisone produced by 5β-reductase (AKR1D1) in the liver, existing as a mixture of isomers.

Tetrahydrocortisol（四氢皮质醇）是一种神经类固醇和皮质醇的代谢物，是一种GABAA受体的拮抗剂，还能够降低眼压。

NCX1022 is a NO-releasing derivative of Hydrocortisone. It is the most widely used anti-inflammatory drug for the treatment of skin inflammation.

Antidepressant agent 8 (Compound 1f) 是 NMDA receptor GluN1 2A 的选择性拮抗剂，其IC50为2.94 μmol L。在Hydrocortisone诱发的斑马鱼抑郁模型中表现出抗抑郁样作用，并且具有良好的血脑屏障穿透性。

Tixocortol pivalate is a corticosteroid that has anti-inflammatory properties similar to hydrocortisone.

Tinoridine hydrochloride (Y-3642 hydrochloride) 是非甾体抗炎药，具有显著的自由基清除和抗过氧化物特性。

Cipamfylline is a xanthine, a theophylline analogue, and is a potent and selective inhibitor of phosphodiesterase type 4 (PDE-4). Cipamfylline was tested in patients with a diagnosis of atopic dermatitis and in two human models of acute and chronic irritant contact dermatitis. The outcome of the study revealed that cipamfylline was more effective than vehicle in treating atopic dermatitis, but less effective than a group II steroid, hydrocortisone-17-butyrate both in the treatment of atopic dermatitis and irritant contact dermatitis. The absorption of cipamfylline and the subsequent systemic exposure might be the reason why further clinical studies with higher doses of cipamfylline have not been published.