cck

CCK-A receptor inhibitor 1 是一种有效的缩胆囊素 A (CCK-A) 受体抑制剂(IC50：340 nM）。CCK-A receptor inhibitor 1 可用于研究与消化系统相关的疾病。

Gastrin/CCK antagonist 1 是一种有效的 gastrin/CCK 拮抗剂，可用于研究代谢系统相关疾病。

CCK (26-30) is an N-terminal fragment of CCK , a peptide hormone found in the intestine and brain that stimulates digestion, mediates satiety, and is involved in anxiety. The sulfated form of CCK (26-30) inhibits binding of [125I]CCK-33 to guinea pig cortical membranes by 10% when used at a concentration of 0.1 mM.

CCK (26-31) is an N-terminal fragment of CCK , a peptide hormone found in the intestine and brain that stimulates digestion, mediates satiety, and is involved in anxiety.

CCK (26-31) is an N-terminal fragment of CCK , a peptide hormone found in the intestine and brain that stimulates digestion, mediates satiety, and is involved in anxiety. The sulfated form of CCK (26-31) inhibits binding of [125I]CCK-33 to guinea pig cortical membranes by 21% when used at a concentration of 0.1 mM.

CCK (27-33) is a C-terminal fragment of CCK , a peptide hormone found in the intestine and brain that stimulates digestion, mediates satiety, and is involved in anxiety. Non-sulfated CCK (27-33) inhibits binding of [3H]naloxone in rat cerebellum membranes (IC50 = 4 uM) and inhibits electrically-stimulated contraction of isolated guinea pig ileum (IC50 = 17 uM), an effect that can be reversed by naloxone. Unlike sulfated CCK (27-33), the non-sulfated form does not reduce exploratory behavior in mice when administered at doses up to 1 uMol/kg.

CCK Octapeptide, non-sulfated acetate 是一种合成的胆囊收缩素脱硫酸肽。

(Iso)-FK-480 是一种新型可口服的胆囊收缩素 A（CCK-A）拮抗剂，可用于研究治疗慢性胰腺炎。

A-65186 是一种选择性A型谷氨酸基胆囊收缩素 （CCK） 拮抗剂，可用于研究炎症和胃肠道损伤。

GV-150013X ((S)-1-(1-(adamantan-1-ylmethyl)-2,4-dioxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepin-3-yl)-3-phenylurea) 是一种有效的CCKB 拮抗剂，pKi= 9.02。

Pranazepide (FK 480) 是一种小分子胆囊收缩素受体拮抗剂，可用于研究消化系统疾病和胰腺炎。

Spiroglumide 是一种CCKB-胃泌素拮抗剂，能够抑制剂量依赖性五肽胃泌素诱导的酸分泌过多，其ID50为20.1（8.67-46.4）mg / kg，可用于探索胃泌素在调节人类胃酸分泌中的生理作用。

Lorglumide sodium salt (CR-1409 sodium salt) 是胆囊收缩素受体 (CCK) 的拮抗剂。

Ceruletide Ammonium acetate (FI-6934 Ammonium acetate) 是一种胆囊收缩素 (CCK) 受体激动剂。它是一种安全有效的胆囊动力剂和小肠和胰腺外分泌兴奋剂。

L-365260 是一种可口服且具有选择性和高效性的非肽胃泌素和脑胆囊收缩素受体 (CCK-B) 拮抗剂。L-365260 抑制 CCK-8S 诱导的 [Ca2+]i 增加，可阻断应激引起的内脏超敏反应，可阻断 CCK-4 的抗探索作用，可用于研究神经系统Ojibwa和内分泌疾病。

Loxiglumide (CR-1505) 是一种缩胆囊素受体拮抗剂。

WAY-620645 是一种 CCK 拮抗剂，具有抗肿瘤和镇痛活性。

Sincalide (CCK-8) 是一种速效的胆囊收缩素的氨基酸多肽激素类似物，可在胆囊造影术中静脉使用。它的肝胆生理作用是增加胆汁的分泌，使胆囊收缩并使 Oddi 的括约肌松弛，从而使胆汁排入十二指肠。它是一种通过注射促进胆囊收缩并帮助诊断胆囊和胰腺疾病的药物。

Sincalide ammonium (CCK-8 ammonium) 是一种有效的氨基酸多肽激素胆囊收缩素 (CCK) 的类似物，是保留了 CCK 的大部分生物活性的活性片段。Sincalide ammonium 促进胆汁的分泌，使胆囊收缩并使 Oddi 的括约肌松弛，从而促进胆汁排入十二指肠。Sincalide ammonium 可通过注射促进胆囊收缩，常用于辅助诊断胆囊、胰腺疾病和胆囊造影术。

[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P acetate ([D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P acetate (96736-12-8 free base)) 是广谱神经肽反向激动剂和拮抗剂。 ghrelin 受体的强效完全反向激动剂(EC50 = 5.2 nM)；减少组成型生长素释放肽受体信号传导。它也是速激肽、缓激肽、CCK 和铃蟾肽受体的拮抗剂。在体外诱导细胞凋亡并抑制癌细胞生长。

Cholecystokinin (26-33) free acid 是胆囊收缩素 (CCK) 的一部分， 是脊椎动物中枢神经系统中存在的 CCKB 型受体的高选择性配体，可诱导大鼠轻度味觉厌恶条件反射。

CCK-B Receptor Antagonist 2 is a potent and orally active antagonist of Gastrin/CCK-B (IC50: 0.43 nM). It also inhibits gastrin/CCK-A activity (IC50: 1.82 μM).

CCK-B Receptor Antagonist 1 is a cholecystokinin B (CCK-B) receptor agonist and has the potential of reducing the secretion of gastric acid.

CCK2R Ligand-Linker Conjugate 1 is a hydrophilic peptide linker that conjugates to the cytotoxic antimicrotubule agents Desacetyl Vinblastine Hydrazide (DAVBH) and Tubulysin B Hydrazide (TubBH) as ligand-linker conjugates[1].