beta plaques

CRANAD-28 是一种血脑屏障（BBB）穿透型双光子成像探头，能够显示淀粉样蛋白斑块，可以标记斑块和脑淀粉样血管病。

BIBD-124 通过与淀粉样蛋白 (Aβ) 斑块结合，展现出优异的亲和力，其 IC50 值达到了 9.51 nM。作为一种放射性示踪剂，[18F]BIBD-124 能够针对 Aβ 斑块进行高效的标记。

Remternetug为一种人源化IgG1-kappa型单克隆抗体，针对APP (Aβ42 N3pGlu)的特定焦谷氨酸形式。该抗体能够特异性识别并结合形成淀粉样斑块的Aβ聚集体。

β-Amyloid (11-22) is a peptide fragment of β-Amyloid. Beta-amyloid peptide (Abeta), the primary component of amyloid plaques in the brains of Alzheimer’s patients, is believed to be the cause of Alzheimer’s Disease (AD), the most common neurodegenerative disorder.

Amyloid precursor c-terminal peptide has the amino acid sequence Gly-Tyr-Glu-Asn-Pro-Thr-Tyr-Lys-Phe-Phe-Glu-Gln-Met-Gln-Asn. APP is best known as the precursor molecule whose proteolysis generates beta-amyloid (Aβ), a 37 to 49 amino acid peptide whose am